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HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages.
Das Gupta K, Ramnath D, von Pein JB, Curson JEB, Wang Y, Abrol R, Kakkanat A, Moradi SV, Gunther KS, Murthy AMV, Stocks CJ, Kapetanovic R, Reid RC, Iyer A, Ilka ZC, Nauseef WM, Plan M, Luo L, Stow JL, Schroder K, Karunakaran D, Alexandrov K, Shakespear MR, Schembri MA, Fairlie DP, Sweet MJ. Das Gupta K, et al. Among authors: kakkanat a. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2212813120. doi: 10.1073/pnas.2212813120. Epub 2023 Jan 17. Proc Natl Acad Sci U S A. 2023. PMID: 36649417 Free PMC article.
The role of H4 flagella in Escherichia coli ST131 virulence.
Kakkanat A, Totsika M, Schaale K, Duell BL, Lo AW, Phan MD, Moriel DG, Beatson SA, Sweet MJ, Ulett GC, Schembri MA. Kakkanat A, et al. Sci Rep. 2015 Nov 9;5:16149. doi: 10.1038/srep16149. Sci Rep. 2015. PMID: 26548325 Free PMC article.
Outbreak of multi-drug-resistant (MDR) Shigella flexneri in northern Australia due to an endemic regional clone acquiring an IncFII plasmid.
Guglielmino CJD, Kakkanat A, Forde BM, Rubenach S, Merone L, Stafford R, Graham RMA, Beatson SA, Jennison AV. Guglielmino CJD, et al. Among authors: kakkanat a. Eur J Clin Microbiol Infect Dis. 2021 Feb;40(2):279-286. doi: 10.1007/s10096-020-04029-w. Epub 2020 Sep 4. Eur J Clin Microbiol Infect Dis. 2021. PMID: 32888117 Free PMC article.
Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic Escherichia coli Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5.
Acharya D, Sullivan MJ, Duell BL, Goh KGK, Katupitiya L, Gosling D, Chamoun MN, Kakkanat A, Chattopadhyay D, Crowley M, Crossman DK, Schembri MA, Ulett GC. Acharya D, et al. Among authors: kakkanat a. mSphere. 2019 Nov 27;4(6):e00545-19. doi: 10.1128/mSphere.00545-19. mSphere. 2019. PMID: 31776239 Free PMC article.
The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host-pathogen interactions.
Mavromatis CH, Bokil NJ, Totsika M, Kakkanat A, Schaale K, Cannistraci CV, Ryu T, Beatson SA, Ulett GC, Schembri MA, Sweet MJ, Ravasi T. Mavromatis CH, et al. Among authors: kakkanat a. Cell Microbiol. 2015 May;17(5):730-46. doi: 10.1111/cmi.12397. Epub 2015 Jan 24. Cell Microbiol. 2015. PMID: 25410299 Free PMC article.