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Items: 1 to 20 of 231

1.

Efficient Inhibition of Avian and Seasonal Influenza A Viruses by a Virus-Specific Dicer-Substrate Small Interfering RNA Swarm in Human Monocyte-Derived Macrophages and Dendritic Cells.

Jiang M, Österlund P, Westenius V, Guo D, Poranen MM, Bamford DH, Julkunen I.

J Virol. 2019 Feb 5;93(4). pii: e01916-18. doi: 10.1128/JVI.01916-18. Print 2019 Feb 15.

PMID:
30463970
2.

Highly Pathogenic H5N1 Influenza A Virus Spreads Efficiently in Human Primary Monocyte-Derived Macrophages and Dendritic Cells.

Westenius V, Mäkelä SM, Julkunen I, Österlund P.

Front Immunol. 2018 Jul 17;9:1664. doi: 10.3389/fimmu.2018.01664. eCollection 2018.

3.

Interleukin-5, interleukin-6, interferon induced protein-10, procalcitonin and C-reactive protein among mechanically ventilated severe community-acquired viral and bacterial pneumonia patients.

Karhu J, Ala-Kokko TI, Vuorinen T, Ohtonen P, Julkunen I, Syrjälä HT.

Cytokine. 2019 Jan;113:272-276. doi: 10.1016/j.cyto.2018.07.019. Epub 2018 Jul 25.

4.

Narcolepsy Associated with Pandemrix Vaccine.

Sarkanen T, Alakuijala A, Julkunen I, Partinen M.

Curr Neurol Neurosci Rep. 2018 Jun 1;18(7):43. doi: 10.1007/s11910-018-0851-5. Review.

PMID:
29855798
5.

Novel activities of safe-in-human broad-spectrum antiviral agents.

Ianevski A, Zusinaite E, Kuivanen S, Strand M, Lysvand H, Teppor M, Kakkola L, Paavilainen H, Laajala M, Kallio-Kokko H, Valkonen M, Kantele A, Telling K, Lutsar I, Letjuka P, Metelitsa N, Oksenych V, Bjørås M, Nordbø SA, Dumpis U, Vitkauskiene A, Öhrmalm C, Bondeson K, Bergqvist A, Aittokallio T, Cox RJ, Evander M, Hukkanen V, Marjomaki V, Julkunen I, Vapalahti O, Tenson T, Merits A, Kainov D.

Antiviral Res. 2018 Jun;154:174-182. doi: 10.1016/j.antiviral.2018.04.016. Epub 2018 Apr 23.

PMID:
29698664
6.

Influenza virus infections from 0 to 2 years of age: A birth cohort study.

Teros-Jaakkola T, Toivonen L, Schuez-Havupalo L, Karppinen S, Julkunen I, Waris M, Peltola V.

J Microbiol Immunol Infect. 2017 Dec 7. pii: S1684-1182(17)30258-X. doi: 10.1016/j.jmii.2017.10.007. [Epub ahead of print]

7.

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.

Bulanova D, Ianevski A, Bugai A, Akimov Y, Kuivanen S, Paavilainen H, Kakkola L, Nandania J, Turunen L, Ohman T, Ala-Hongisto H, Pesonen HM, Kuisma MS, Honkimaa A, Walton EL, Oksenych V, Lorey MB, Guschin D, Shim J, Kim J, Than TT, Chang SY, Hukkanen V, Kulesskiy E, Marjomaki VS, Julkunen I, Nyman TA, Matikainen S, Saarela JS, Sane F, Hober D, Gabriel G, De Brabander JK, Martikainen M, Windisch MP, Min JY, Bruzzone R, Aittokallio T, Vähä-Koskela M, Vapalahti O, Pulk A, Velagapudi V, Kainov DE.

Viruses. 2017 Sep 25;9(10). pii: E271. doi: 10.3390/v9100271.

8.

Ebolavirus protein VP24 interferes with innate immune responses by inhibiting interferon-λ1 gene expression.

He F, Melén K, Maljanen S, Lundberg R, Jiang M, Österlund P, Kakkola L, Julkunen I.

Virology. 2017 Sep;509:23-34. doi: 10.1016/j.virol.2017.06.002. Epub 2017 Jun 5.

9.

Production, purification and immunogenicity of recombinant Ebola virus proteins - A comparison of Freund's adjuvant and adjuvant system 03.

Melén K, Kakkola L, He F, Airenne K, Vapalahti O, Karlberg H, Mirazimi A, Julkunen I.

J Virol Methods. 2017 Apr;242:35-45. doi: 10.1016/j.jviromet.2016.12.014. Epub 2016 Dec 24.

PMID:
28025125
10.

Regulation of kynurenine biosynthesis during influenza virus infection.

Gaelings L, Söderholm S, Bugai A, Fu Y, Nandania J, Schepens B, Lorey MB, Tynell J, Vande Ginste L, Le Goffic R, Miller MS, Kuisma M, Marjomäki V, De Brabander J, Matikainen S, Nyman TA, Bamford DH, Saelens X, Julkunen I, Paavilainen H, Hukkanen V, Velagapudi V, Kainov DE.

FEBS J. 2017 Jan;284(2):222-236. doi: 10.1111/febs.13966. Epub 2016 Dec 14.

11.

Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes.

Anastasina M, Le May N, Bugai A, Fu Y, Söderholm S, Gaelings L, Ohman T, Tynell J, Kyttänen S, Barboric M, Nyman TA, Matikainen S, Julkunen I, Butcher SJ, Egly JM, Kainov DE.

Biochim Biophys Acta. 2016 Nov;1859(11):1440-1448. doi: 10.1016/j.bbagrm.2016.09.005. Epub 2016 Sep 21.

PMID:
27664935
12.

Nuclear Translocation of Crk Adaptor Proteins by the Influenza A Virus NS1 Protein.

Ylösmäki L, Fagerlund R, Kuisma I, Julkunen I, Saksela K.

Viruses. 2016 Apr 15;8(4):101. doi: 10.3390/v8040101.

13.

Probiotics and respiratory and gastrointestinal tract infections in Finnish military conscripts - a randomised placebo-controlled double-blinded study.

Kalima K, Lehtoranta L, He L, Pitkäniemi J, Lundell R, Julkunen I, Roivainen M, Närkiö M, Mäkelä MJ, Siitonen S, Korpela R, Pitkäranta A.

Benef Microbes. 2016 Sep;7(4):463-71. doi: 10.3920/BM2015.0172. Epub 2016 Apr 6.

PMID:
27048835
14.

Spectrally and Spatially Multiplexed Serological Array-in-Well Assay Utilizing Two-Color Upconversion Luminescence Imaging.

Kale V, Päkkilä H, Vainio J, Ahomaa A, Sirkka N, Lyytikäinen A, Talha SM, Kutsaya A, Waris M, Julkunen I, Soukka T.

Anal Chem. 2016 Apr 19;88(8):4470-7. doi: 10.1021/acs.analchem.6b00337. Epub 2016 Mar 29.

PMID:
26996057
15.

Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication.

Balistreri G, Viiliäinen J, Turunen M, Diaz R, Lyly L, Pekkonen P, Rantala J, Ojala K, Sarek G, Teesalu M, Denisova O, Peltonen K, Julkunen I, Varjosalo M, Kainov D, Kallioniemi O, Laiho M, Taipale J, Hautaniemi S, Ojala PM.

PLoS Pathog. 2016 Feb 18;12(2):e1005424. doi: 10.1371/journal.ppat.1005424. eCollection 2016 Feb.

16.

Immuno-modulating properties of saliphenylhalamide, SNS-032, obatoclax, and gemcitabine.

Söderholm S, Anastasina M, Islam MM, Tynell J, Poranen MM, Bamford DH, Stenman J, Julkunen I, Šaulienė I, De Brabander JK, Matikainen S, Nyman TA, Saelens X, Kainov D.

Antiviral Res. 2016 Feb;126:69-80. doi: 10.1016/j.antiviral.2015.12.011. Epub 2015 Dec 29.

17.

Prospective clinical and serological follow-up in early childhood reveals a high rate of subclinical RSV infection and a relatively high reinfection rate within the first 3 years of life.

Kutsaya A, Teros-Jaakkola T, Kakkola L, Toivonen L, Peltola V, Waris M, Julkunen I.

Epidemiol Infect. 2016 Jun;144(8):1622-33. doi: 10.1017/S0950268815003143. Epub 2016 Jan 6.

PMID:
26732801
18.

Interferons Induce STAT1-Dependent Expression of Tissue Plasminogen Activator, a Pathogenicity Factor in Puumala Hantavirus Disease.

Strandin T, Hepojoki J, Laine O, Mäkelä S, Klingström J, Lundkvist Å, Julkunen I, Mustonen J, Vaheri A.

J Infect Dis. 2016 May 15;213(10):1632-41. doi: 10.1093/infdis/jiv764. Epub 2015 Dec 23.

PMID:
26704613
19.

Middle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocyte-derived macrophages and dendritic cells.

Tynell J, Westenius V, Rönkkö E, Munster VJ, Melén K, Österlund P, Julkunen I.

J Gen Virol. 2016 Feb;97(2):344-55. doi: 10.1099/jgv.0.000351. Epub 2015 Nov 24.

20.

RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression.

Mäkelä SM, Österlund P, Westenius V, Latvala S, Diamond MS, Gale M Jr, Julkunen I.

J Virol. 2015 Dec;89(23):12014-25. doi: 10.1128/JVI.01576-15. Epub 2015 Sep 16.

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