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Items: 9


Prophylactic benefits of systemically delivered simvastatin treatment in a house dust mite challenged murine model of allergic asthma.

Jha A, Ryu MH, Oo O, Bews HJ, Carlson JC, Schwartz J, Basu S, Wong CS, Halayko AJ.

Br J Pharmacol. 2018 Apr;175(7):1004-1016. doi: 10.1111/bph.14140. Epub 2018 Feb 27.


Tumor necrosis factor regulates NMDA receptor-mediated airway smooth muscle contractile function and airway responsiveness.

Anaparti V, Pascoe CD, Jha A, Mahood TH, Ilarraza R, Unruh H, Moqbel R, Halayko AJ.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L467-80. doi: 10.1152/ajplung.00382.2015. Epub 2016 Jul 1.


High-mobility group box 1 promotes extracellular matrix synthesis and wound repair in human bronchial epithelial cells.

Ojo OO, Ryu MH, Jha A, Unruh H, Halayko AJ.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1354-66. doi: 10.1152/ajplung.00054.2015. Epub 2015 Oct 2.


Characterization of the dystrophin-glycoprotein complex in airway smooth muscle: role of δ-sarcoglycan in airway responsiveness.

Sharma P, Jha A, Stelmack GL, Detillieux K, Basu S, Klonisch T, Unruh H, Halayko AJ.

Can J Physiol Pharmacol. 2015 Mar;93(3):195-202. doi: 10.1139/cjpp-2014-0389. Epub 2015 Jan 14.


A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness?

Jha A, Sharma P, Anaparti V, Ryu MH, Halayko AJ.

Can J Physiol Pharmacol. 2015 Mar;93(3):171-6. doi: 10.1139/cjpp-2014-0417. Epub 2015 Jan 5. Review.


Chronic exposure to perfluorinated compounds: Impact on airway hyperresponsiveness and inflammation.

Ryu MH, Jha A, Ojo OO, Mahood TH, Basu S, Detillieux KA, Nikoobakht N, Wong CS, Loewen M, Becker AB, Halayko AJ.

Am J Physiol Lung Cell Mol Physiol. 2014 Nov 15;307(10):L765-74. doi: 10.1152/ajplung.00100.2014. Epub 2014 Sep 12.


Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins.

Ghavami S, Sharma P, Yeganeh B, Ojo OO, Jha A, Mutawe MM, Kashani HH, Los MJ, Klonisch T, Unruh H, Halayko AJ.

Biochim Biophys Acta. 2014 Jul;1843(7):1259-71. doi: 10.1016/j.bbamcr.2014.03.006. Epub 2014 Mar 15.


Simultaneous quantification of simvastatin and simvastatin hydroxy acid in blood serum at physiological pH by ultrahigh performance liquid chromatography-tandem mass spectrometry (UHPLC/MS/MS).

Bews HJ, Carlson JC, Jha A, Basu S, Halayko AJ, Wong CS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Feb 1;947-948:145-50. doi: 10.1016/j.jchromb.2013.12.030. Epub 2013 Dec 31.


Models to study airway smooth muscle contraction in vivo, ex vivo and in vitro: implications in understanding asthma.

Wright D, Sharma P, Ryu MH, Rissé PA, Ngo M, Maarsingh H, Koziol-White C, Jha A, Halayko AJ, West AR.

Pulm Pharmacol Ther. 2013 Feb;26(1):24-36. doi: 10.1016/j.pupt.2012.08.006. Epub 2012 Aug 28. Review.


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