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Items: 1 to 20 of 175

1.

Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties.

Cochet F, Facchini FA, Zaffaroni L, Billod JM, Coelho H, Holgado A, Braun H, Beyaert R, Jerala R, Jimenez-Barbero J, Martin-Santamaria S, Peri F.

Sci Rep. 2019 Jan 29;9(1):919. doi: 10.1038/s41598-018-37421-w.

2.

Recombinant flagellins with deletions in domains D1, D2, and D3: Characterization as novel immunoadjuvants.

Biedma ME, Cayet D, Tabareau J, Rossi AH, Ivičak-Kocjan K, Moreno G, Errea A, Soulard D, Parisi G, Jerala R, Berguer P, Rumbo M, Sirard JC.

Vaccine. 2019 Jan 21;37(4):652-663. doi: 10.1016/j.vaccine.2018.12.009. Epub 2018 Dec 21.

PMID:
30583910
3.

Design of fast proteolysis-based signaling and logic circuits in mammalian cells.

Fink T, Lonzarić J, Praznik A, Plaper T, Merljak E, Leben K, Jerala N, Lebar T, Strmšek Ž, Lapenta F, Benčina M, Jerala R.

Nat Chem Biol. 2019 Feb;15(2):115-122. doi: 10.1038/s41589-018-0181-6. Epub 2018 Dec 10.

PMID:
30531965
4.

NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway.

Hafner-Bratkovič I, Sušjan P, Lainšček D, Tapia-Abellán A, Cerović K, Kadunc L, Angosto-Bazarra D, Pelegrίn P, Jerala R.

Nat Commun. 2018 Dec 5;9(1):5182. doi: 10.1038/s41467-018-07573-4.

5.

Delivery of an artificial transcription regulator dCas9-VPR by extracellular vesicles for therapeutic gene activation.

Lainšček D, Kadunc L, Manček-Keber M, Hafner-Bratkovič I, Romih R, Jerala R.

ACS Synth Biol. 2018 Dec 4. doi: 10.1021/acssynbio.8b00192. [Epub ahead of print]

PMID:
30513193
6.

DNA-Free Genome Editing of Brassica oleracea and B. rapa Protoplasts Using CRISPR-Cas9 Ribonucleoprotein Complexes.

Murovec J, Guček K, Bohanec B, Avbelj M, Jerala R.

Front Plant Sci. 2018 Nov 5;9:1594. doi: 10.3389/fpls.2018.01594. eCollection 2018.

7.

Polarized displacement by transcription activator-like effectors for regulatory circuits.

Lebar T, Verbič A, Ljubetič A, Jerala R.

Nat Chem Biol. 2019 Jan;15(1):80-87. doi: 10.1038/s41589-018-0163-8. Epub 2018 Nov 19.

PMID:
30455466
8.

SwitCCh: Metal-Site Design for Controlling the Assembly of a Coiled-Coil Homodimer.

Aupič J, Lapenta F, Jerala R.

Chembiochem. 2018 Dec 4;19(23):2453-2457. doi: 10.1002/cbic.201800578. Epub 2018 Oct 30.

PMID:
30260542
9.

Extension and refinement of the recognition motif for Toll-like receptor 5 activation by flagellin.

Ivičak-Kocjan K, Forstnerič V, Panter G, Jerala R, Benčina M.

J Leukoc Biol. 2018 Oct;104(4):767-776. doi: 10.1002/JLB.3VMA0118-035R. Epub 2018 Jun 19.

PMID:
29920759
10.

Peptide and protein nanotechnology into the 2020s: beyond biology.

Ulijn RV, Jerala R.

Chem Soc Rev. 2018 May 21;47(10):3391-3394. doi: 10.1039/c8cs90055h. No abstract available.

PMID:
29761188
11.

Designed Transcriptional Regulation in Mammalian Cells Based on TALE- and CRISPR/dCas9.

Lebar T, Jerala R.

Methods Mol Biol. 2018;1772:191-203. doi: 10.1007/978-1-4939-7795-6_10.

PMID:
29754229
12.

Publisher Correction: Phosphodiester backbone of the CpG motif within immunostimulatory oligodeoxynucleotides augments activation of Toll-like receptor 9.

Pohar J, Lainšček D, Kunšek A, Cajnko MM, Jerala R, Benčina M.

Sci Rep. 2018 Mar 6;8(1):4269. doi: 10.1038/s41598-018-22376-9.

13.

Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists.

Facchini FA, Zaffaroni L, Minotti A, Rapisarda S, Calabrese V, Forcella M, Fusi P, Airoldi C, Ciaramelli C, Billod JM, Schromm AB, Braun H, Palmer C, Beyaert R, Lapenta F, Jerala R, Pirianov G, Martin-Santamaria S, Peri F.

J Med Chem. 2018 Apr 12;61(7):2895-2909. doi: 10.1021/acs.jmedchem.7b01803. Epub 2018 Mar 12.

14.

Coiled coil protein origami: from modular design principles towards biotechnological applications.

Lapenta F, Aupič J, Strmšek Ž, Jerala R.

Chem Soc Rev. 2018 May 21;47(10):3530-3542. doi: 10.1039/c7cs00822h. Review.

PMID:
29400389
15.

Extracellular vesicle-mediated transfer of constitutively active MyD88L265P engages MyD88wt and activates signaling.

Manček-Keber M, Lainšček D, Benčina M, Chen JG, Romih R, Hunter ZR, Treon SP, Jerala R.

Blood. 2018 Apr 12;131(15):1720-1729. doi: 10.1182/blood-2017-09-805499. Epub 2018 Jan 22.

PMID:
29358175
16.

Publisher Correction: Phosphodiester backbone of the CpG motif within immunostimulatory oligodeoxynucleotides augments activation of Toll-like receptor 9.

Pohar J, Lainšček D, Kunšek A, Cajnko MM, Jerala R, Benčina M.

Sci Rep. 2018 Jan 5;8(1):355. doi: 10.1038/s41598-017-17988-6.

17.

Identification of novel alleles associated with insulin resistance in childhood obesity using pooled-DNA genome-wide association study approach.

Kotnik P, Knapič E, Kokošar J, Kovač J, Jerala R, Battelino T, Horvat S.

Int J Obes (Lond). 2018 Apr;42(4):686-695. doi: 10.1038/ijo.2017.293. Epub 2017 Nov 30.

18.

The role of N-terminal segment and membrane association in MyD88-mediated signaling.

Avbelj M, Panter G, Jerala R.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):878-883. doi: 10.1016/j.bbrc.2017.11.099. Epub 2017 Nov 16.

PMID:
29155181
19.

Phosphodiester backbone of the CpG motif within immunostimulatory oligodeoxynucleotides augments activation of Toll-like receptor 9.

Pohar J, Lainšček D, Kunšek A, Cajnko MM, Jerala R, Benčina M.

Sci Rep. 2017 Nov 6;7(1):14598. doi: 10.1038/s41598-017-15178-y. Erratum in: Sci Rep. 2018 Jan 5;8(1):355. Sci Rep. 2018 Mar 6;8(1):4269.

20.

Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo.

Ljubetič A, Lapenta F, Gradišar H, Drobnak I, Aupič J, Strmšek Ž, Lainšček D, Hafner-Bratkovič I, Majerle A, Krivec N, Benčina M, Pisanski T, Veličković TĆ, Round A, Carazo JM, Melero R, Jerala R.

Nat Biotechnol. 2017 Nov;35(11):1094-1101. doi: 10.1038/nbt.3994. Epub 2017 Oct 16.

PMID:
29035374

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