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Items: 1 to 20 of 31

1.

Reward and aversion processing in patients with post-traumatic stress disorder: functional neuroimaging with visual and thermal stimuli.

Elman I, Upadhyay J, Langleben DD, Albanese M, Becerra L, Borsook D.

Transl Psychiatry. 2018 Nov 2;8(1):240. doi: 10.1038/s41398-018-0292-6.

2.

The role of fMRI in drug development.

Carmichael O, Schwarz AJ, Chatham CH, Scott D, Turner JA, Upadhyay J, Coimbra A, Goodman JA, Baumgartner R, English BA, Apolzan JW, Shankapal P, Hawkins KR.

Drug Discov Today. 2018 Feb;23(2):333-348. doi: 10.1016/j.drudis.2017.11.012. Epub 2017 Nov 15. Review.

3.

A critical evaluation of validity and utility of translational imaging in pain and analgesia: Utilizing functional imaging to enhance the process.

Upadhyay J, Geber C, Hargreaves R, Birklein F, Borsook D.

Neurosci Biobehav Rev. 2018 Jan;84:407-423. doi: 10.1016/j.neubiorev.2017.08.004. Epub 2017 Aug 12. Review.

4.

The Expansion of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva Is Activin A-Dependent.

Upadhyay J, Xie L, Huang L, Das N, Stewart RC, Lyon MC, Palmer K, Rajamani S, Graul C, Lobo M, Wellman TJ, Soares EJ, Silva MD, Hesterman J, Wang L, Wen X, Qian X, Nannuru K, Idone V, Murphy AJ, Economides AN, Hatsell SJ.

J Bone Miner Res. 2017 Dec;32(12):2489-2499. doi: 10.1002/jbmr.3235. Epub 2017 Sep 22.

5.

Detection of central circuits implicated in the formation of novel pain memories.

Upadhyay J, Granitzka J, Bauermann T, Baumgärtner U, Breimhorst M, Treede RD, Birklein F.

J Pain Res. 2016 Sep 15;9:671-681. eCollection 2016.

6.

Test-retest reliability of evoked heat stimulation BOLD fMRI.

Upadhyay J, Lemme J, Anderson J, Bleakman D, Large T, Evelhoch JL, Hargreaves R, Borsook D, Becerra L.

J Neurosci Methods. 2015 Sep 30;253:38-46. doi: 10.1016/j.jneumeth.2015.06.001. Epub 2015 Jun 10.

PMID:
26072245
7.

Multimodal assessment of nervous and immune system responses following sciatic nerve injury.

Lasko L, Huang X, Voorbach MJ, Lewis LG, Stavropoulos J, Carriker J, Seifert TR, Baker SJ, Upadhyay J.

Pain. 2013 Dec;154(12):2782-93. doi: 10.1016/j.pain.2013.08.016. Epub 2013 Aug 21.

PMID:
23973359
8.

Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects.

Becerra L, Upadhyay J, Chang PC, Bishop J, Anderson J, Baumgartner R, Schwarz AJ, Coimbra A, Wallin D, Nutile L, George E, Maier G, Sunkaraneni S, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Borsook D.

J Pharmacol Exp Ther. 2013 Apr;345(1):41-51. doi: 10.1124/jpet.112.201145. Epub 2013 Jan 31.

PMID:
23370795
9.

Pain facilitation brain regions activated by nalbuphine are revealed by pharmacological fMRI.

Gear R, Becerra L, Upadhyay J, Bishop J, Wallin D, Pendse G, Levine J, Borsook D.

PLoS One. 2013;8(1):e50169. doi: 10.1371/journal.pone.0050169. Epub 2013 Jan 8.

10.

Pharmacological modulation of brain activity in a preclinical model of osteoarthritis.

Upadhyay J, Baker SJ, Rajagovindan R, Hart M, Chandran P, Hooker BA, Cassar S, Mikusa JP, Tovcimak A, Wald MJ, Joshi SK, Bannon A, Medema JK, Beaver J, Honore P, Kamath RV, Fox GB, Day M.

Neuroimage. 2013 Jan 1;64:341-55. doi: 10.1016/j.neuroimage.2012.08.084. Epub 2012 Sep 7.

PMID:
22982372
11.

Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain.

Borsook D, Upadhyay J, Klimas M, Schwarz AJ, Coimbra A, Baumgartner R, George E, Potter WZ, Large T, Bleakman D, Evelhoch J, Iyengar S, Becerra L, Hargreaves RJ.

Drug Discov Today. 2012 Sep;17(17-18):964-73. doi: 10.1016/j.drudis.2012.05.004. Epub 2012 May 10. Review.

PMID:
22579743
12.

Default-mode-like network activation in awake rodents.

Upadhyay J, Baker SJ, Chandran P, Miller L, Lee Y, Marek GJ, Sakoglu U, Chin CL, Luo F, Fox GB, Day M.

PLoS One. 2011;6(11):e27839. doi: 10.1371/journal.pone.0027839. Epub 2011 Nov 18.

13.

Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine.

Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Schwarz AJ, Pendse G, Wallin D, Nutile L, Bishop J, George E, Elman I, Sunkaraneni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D.

Neuroimage. 2012 Feb 15;59(4):3762-73. doi: 10.1016/j.neuroimage.2011.11.034. Epub 2011 Nov 18.

PMID:
22119647
14.

Imaging drugs with and without clinical analgesic efficacy.

Upadhyay J, Anderson J, Schwarz AJ, Coimbra A, Baumgartner R, Pendse G, George E, Nutile L, Wallin D, Bishop J, Neni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D.

Neuropsychopharmacology. 2011 Dec;36(13):2659-73. doi: 10.1038/npp.2011.156. Epub 2011 Aug 17.

15.

A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #1: processes and requirements.

Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D.

Drug Discov Today. 2011 Jul;16(13-14):583-93. doi: 10.1016/j.drudis.2011.05.006. Epub 2011 May 24. Review.

PMID:
21635967
16.

A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices.

Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D.

Drug Discov Today. 2011 Aug;16(15-16):671-82. doi: 10.1016/j.drudis.2011.03.011. Epub 2011 Apr 6. Review.

PMID:
21477664
17.

Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: implications for photophobia.

Maleki N, Becerra L, Upadhyay J, Burstein R, Borsook D.

Hum Brain Mapp. 2012 Jan;33(1):75-88. doi: 10.1002/hbm.21194. Epub 2011 Feb 17.

18.

Paradigm shift in translational neuroimaging of CNS disorders.

Sakoğlu U, Upadhyay J, Chin CL, Chandran P, Baker SJ, Cole TB, Fox GB, Day M, Luo F.

Biochem Pharmacol. 2011 Jun 15;81(12):1374-87. doi: 10.1016/j.bcp.2010.12.029. Epub 2011 Jan 8. Review.

PMID:
21219879
19.

Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals.

Chin CL, Upadhyay J, Marek GJ, Baker SJ, Zhang M, Mezler M, Fox GB, Day M.

J Pharmacol Exp Ther. 2011 Mar;336(3):709-15. doi: 10.1124/jpet.110.173880. Epub 2010 Dec 20. Erratum in: J Pharmacol Exp Ther. 2011 May;337(2):567.

PMID:
21172908
20.

Alterations in brain structure and functional connectivity in prescription opioid-dependent patients.

Upadhyay J, Maleki N, Potter J, Elman I, Rudrauf D, Knudsen J, Wallin D, Pendse G, McDonald L, Griffin M, Anderson J, Nutile L, Renshaw P, Weiss R, Becerra L, Borsook D.

Brain. 2010 Jul;133(Pt 7):2098-114. doi: 10.1093/brain/awq138. Epub 2010 Jun 16.

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