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Items: 1 to 20 of 304

1.

Pipe-3D: A Pipeline Based on Immunofluorescence, 3D Confocal Imaging, Reconstructions, and Morphometry for Biliary Network Analysis in Cholestasis.

Damle-Vartak A, Begher-Tibbe B, Gunther G, Geisler F, Vartak N, Hengstler JG.

Methods Mol Biol. 2019;1981:25-53. doi: 10.1007/978-1-4939-9420-5_3.

PMID:
31016646
2.

Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer.

Weisner J, Landel I, Reintjes C, Uhlenbrock N, Trajkovic-Arsic M, Dienstbier N, Hardick J, Ladigan S, Lindemann M, Smith S, Quambusch L, Scheinpflug R, Depta L, Gontla R, Unger A, Müller H, Baumann M, Schultz-Fademrecht C, Günther G, Maghnouj A, Müller MP, Pohl M, Teschendorf C, Wolters H, Viebahn R, Tannapfel A, Uhl W, Hengstler JG, Hahn SA, Siveke JT, Rauh D.

Cancer Res. 2019 May 1;79(9):2367-2378. doi: 10.1158/0008-5472.CAN-18-2861. Epub 2019 Mar 11.

PMID:
30858154
3.

Identification of interactions of binary variables associated with survival time using survivalFS.

Tietz T, Selinski S, Golka K, Hengstler JG, Gripp S, Ickstadt K, Ruczinski I, Schwender H.

Arch Toxicol. 2019 Mar;93(3):585-602. doi: 10.1007/s00204-019-02398-6. Epub 2019 Jan 29.

PMID:
30694373
4.

HR-MAS NMR Based Quantitative Metabolomics in Breast Cancer.

Gogiashvili M, Nowacki J, Hergenröder R, Hengstler JG, Lambert J, Edlund K.

Metabolites. 2019 Jan 22;9(2). pii: E19. doi: 10.3390/metabo9020019. Review.

5.

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.

Cadenas C, Vosbeck S, Edlund K, Grgas K, Madjar K, Hellwig B, Adawy A, Glotzbach A, Stewart JD, Lesjak MS, Franckenstein D, Claus M, Hayen H, Schriewer A, Gianmoena K, Thaler S, Schmidt M, Micke P, Pontén F, Mardinoglu A, Zhang C, Käfferlein HU, Watzl C, Frank S, Rahnenführer J, Marchan R, Hengstler JG.

Int J Cancer. 2019 Jan 17. doi: 10.1002/ijc.32138. [Epub ahead of print]

PMID:
30653260
6.

Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC.

Edlund K, Madjar K, Mattsson JSM, Djureinovic D, Lindskog C, Brunnström H, Koyi H, Brandén E, Jirström K, Pontén F, Rahnenführer J, Micke P, Hengstler JG.

J Thorac Oncol. 2019 Apr;14(4):628-640. doi: 10.1016/j.jtho.2018.12.022. Epub 2019 Jan 9.

7.

Study of correlation between the NAT2 phenotype and genotype status among Greenlandic Inuit.

Birch Kristensen E, Yakimov V, Bjorn-Mortensen K, Soborg B, Koch A, Andersson M, Birch Kristensen K, Michelsen SW, Skotte L, Ahrendt Bjerregaard A, Blaszkewicz M, Golka K, Hengstler JG, Feenstra B, Melbye M, Geller F.

EXCLI J. 2018 Nov 2;17:1043-1053. doi: 10.17179/excli2018-1671. eCollection 2018.

8.

Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes.

Grinberg M, Stöber RM, Albrecht W, Edlund K, Schug M, Godoy P, Cadenas C, Marchan R, Lampen A, Braeuning A, Buhrke T, Leist M, Oberemm A, Hellwig B, Kamp H, Gardner I, Escher S, Taboureau O, Aguayo-Orozco A, Sachinidis A, Ellinger-Ziegelbauer H, Rahnenführer J, Hengstler JG.

Arch Toxicol. 2018 Dec;92(12):3517-3533. doi: 10.1007/s00204-018-2352-3. Epub 2018 Dec 3.

PMID:
30511339
9.

In vitro proteomic analysis of methapyrilene toxicity in rat hepatocytes reveals effects on intermediary metabolism.

Braeuning A, Oberemm A, Heise T, Gundert-Remy U, Hengstler JG, Lampen A.

Arch Toxicol. 2019 Feb;93(2):369-383. doi: 10.1007/s00204-018-2360-3. Epub 2018 Nov 22.

PMID:
30467583
10.

Pyrrolizidine alkaloid-induced alterations of prostanoid synthesis in human endothelial cells.

Ebmeyer J, Behrend J, Lorenz M, Günther G, Reif R, Hengstler JG, Braeuning A, Lampen A, Hessel-Pras S.

Chem Biol Interact. 2019 Jan 25;298:104-111. doi: 10.1016/j.cbi.2018.11.007. Epub 2018 Nov 19.

PMID:
30465738
11.

Genetic determinants of steatosis and fibrosis progression in paediatric non-alcoholic fatty liver disease.

Hudert CA, Selinski S, Rudolph B, Bläker H, Loddenkemper C, Thielhorn R, Berndt N, Golka K, Cadenas C, Reinders J, Henning S, Bufler P, Jansen PLM, Holzhütter HG, Meierhofer D, Hengstler JG, Wiegand S.

Liver Int. 2019 Mar;39(3):540-556. doi: 10.1111/liv.14006. Epub 2018 Dec 21.

PMID:
30444569
12.

Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes.

Gu X, Albrecht W, Edlund K, Kappenberg F, Rahnenführer J, Leist M, Moritz W, Godoy P, Cadenas C, Marchan R, Brecklinghaus T, Pardo LT, Castell JV, Gardner I, Han B, Hengstler JG, Stoeber R.

Arch Toxicol. 2018 Dec;92(12):3505-3515. doi: 10.1007/s00204-018-2302-0. Epub 2018 Oct 13.

PMID:
30317417
13.

The MAK-commission: finding solutions to society's future challenges.

Hengstler JG.

Arch Toxicol. 2018 Nov;92(11):3247-3249. doi: 10.1007/s00204-018-2313-x. Epub 2018 Sep 24. No abstract available.

PMID:
30251053
14.

Contemporary trends in toxicological research on arsenic.

Bolt HM, Hengstler JG.

Arch Toxicol. 2018 Nov;92(11):3251-3253. doi: 10.1007/s00204-018-2311-z. Epub 2018 Sep 22. No abstract available.

PMID:
30244273
15.

Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity.

Köppert S, Büscher A, Babler A, Ghallab A, Buhl EM, Latz E, Hengstler JG, Smith ER, Jahnen-Dechent W.

Front Immunol. 2018 Sep 4;9:1991. doi: 10.3389/fimmu.2018.01991. eCollection 2018.

16.

Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells.

Knaack H, Lenk L, Philipp LM, Miarka L, Rahn S, Viol F, Hauser C, Egberts JH, Gundlach JP, Will O, Tiwari S, Mikulits W, Schumacher U, Hengstler JG, Sebens S.

Oncotarget. 2018 Aug 3;9(60):31771-31786. doi: 10.18632/oncotarget.25884. eCollection 2018 Aug 3.

17.

β-Heregulin impairs EGF induced PLC-γ1 signalling in human breast cancer cells.

Rommerswinkel N, Keil S, Adawy A, Hengstler JG, Niggemann B, Zänker KS, Dittmar T.

Cell Signal. 2018 Dec;52:23-34. doi: 10.1016/j.cellsig.2018.08.016. Epub 2018 Aug 27.

PMID:
30165102
18.

Characterization of hepatocyte-based in vitro systems for reliable toxicity testing.

Vinken M, Hengstler JG.

Arch Toxicol. 2018 Oct;92(10):2981-2986. doi: 10.1007/s00204-018-2297-6. Epub 2018 Aug 23.

PMID:
30141065
19.

Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood.

Ghallab A, Hofmann U, Sezgin S, Vartak N, Hassan R, Zaza A, Godoy P, Schneider KM, Guenther G, Ahmed YA, Abbas AA, Keitel V, Kuepfer L, Dooley S, Lammert F, Trautwein C, Spiteller M, Drasdo D, Hofmann AF, Jansen PLM, Hengstler JG, Reif R.

Hepatology. 2019 Feb;69(2):666-683. doi: 10.1002/hep.30213. Epub 2018 Nov 19.

PMID:
30102412
20.

Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI.

Sezgin S, Hassan R, Zühlke S, Kuepfer L, Hengstler JG, Spiteller M, Ghallab A.

Arch Toxicol. 2018 Sep;92(9):2963-2977. doi: 10.1007/s00204-018-2271-3. Epub 2018 Jul 23.

PMID:
30039229

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