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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1980 1
1981 1
1982 2
1999 1
2000 1
2002 3
2003 1
2004 4
2005 4
2006 12
2007 11
2008 8
2009 11
2010 9
2011 13
2012 11
2013 19
2014 13
2015 11
2016 12
2017 8
2018 7
2019 10
2020 6
2021 14
2022 6
2023 7
2024 0

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197 results

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Page 1
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor.
Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. Fink EA, et al. Among authors: jacobson mp. Science. 2022 Sep 30;377(6614):eabn7065. doi: 10.1126/science.abn7065. Epub 2022 Sep 30. Science. 2022. PMID: 36173843 Free PMC article.
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.
Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, Hellerstein M, Goetzman ES, Gibson BW, Verdin E. Rardin MJ, et al. Among authors: jacobson mp. Cell Metab. 2013 Dec 3;18(6):920-33. doi: 10.1016/j.cmet.2013.11.013. Cell Metab. 2013. PMID: 24315375 Free PMC article.
Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H. Xia S, et al. Among authors: jacobson mp. Nature. 2021 May;593(7860):607-611. doi: 10.1038/s41586-021-03478-3. Epub 2021 Apr 21. Nature. 2021. PMID: 33883744 Free PMC article.
Signal peptide mimicry primes Sec61 for client-selective inhibition.
Rehan S, Tranter D, Sharp PP, Craven GB, Lowe E, Anderl JL, Muchamuel T, Abrishami V, Kuivanen S, Wenzell NA, Jennings A, Kalyanaraman C, Strandin T, Javanainen M, Vapalahti O, Jacobson MP, McMinn D, Kirk CJ, Huiskonen JT, Taunton J, Paavilainen VO. Rehan S, et al. Among authors: jacobson mp. Nat Chem Biol. 2023 Sep;19(9):1054-1062. doi: 10.1038/s41589-023-01326-1. Epub 2023 May 11. Nat Chem Biol. 2023. PMID: 37169961 Free PMC article.
Computer-aided antibody design.
Kuroda D, Shirai H, Jacobson MP, Nakamura H. Kuroda D, et al. Among authors: jacobson mp. Protein Eng Des Sel. 2012 Oct;25(10):507-21. doi: 10.1093/protein/gzs024. Epub 2012 Jun 2. Protein Eng Des Sel. 2012. PMID: 22661385 Free PMC article. Review.
Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.
Paolino J, Dimitrov B, Apsel Winger B, Sandoval-Perez A, Rangarajan AV, Ocasio-Martinez N, Tsai HK, Li Y, Robichaud AL, Khalid D, Hatton C, Gillani R, Polonen P, Dilig A, Gotti G, Kavanagh J, Adhav AA, Gow S, Tsai J, Li Y, Ebert BL, Van Allen EM, Bledsoe J, Kim AS, Tasian SK, Cooper SL, Cooper TM, Hijiya N, Sulis ML, Shukla NN, Magee JA, Mullighan CG, Burke MJ, Luskin MR, Mar BG, Jacobson MP, Harris MH, Stegmaier K, Place AE, Pikman Y. Paolino J, et al. Among authors: jacobson mp. Clin Cancer Res. 2023 Nov 14;29(22):4613-4626. doi: 10.1158/1078-0432.CCR-22-2562. Clin Cancer Res. 2023. PMID: 37725576
Designing molecules to cross biological membranes.
Lokey RS, Liras J, Liras S, Jacobson MP. Lokey RS, et al. Among authors: jacobson mp. Curr Top Med Chem. 2013;13(7):775. doi: 10.2174/1568026611313070001. Curr Top Med Chem. 2013. PMID: 23578022 No abstract available.
Cysteine Oxidation in Proteins: Structure, Biophysics, and Simulation.
Garrido Ruiz D, Sandoval-Perez A, Rangarajan AV, Gunderson EL, Jacobson MP. Garrido Ruiz D, et al. Among authors: jacobson mp. Biochemistry. 2022 Oct 18;61(20):2165-2176. doi: 10.1021/acs.biochem.2c00349. Epub 2022 Sep 26. Biochemistry. 2022. PMID: 36161872 Free PMC article. Review.
197 results