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Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice.
Lakin R, Polidovitch N, Yang S, Parikh M, Liu X, Debi R, Gao X, Chen W, Guzman C, Yakobov S, Izaddoustdar F, Wauchop M, Lei Q, Xu W, Nedospasov SA, Christoffels VM, Backx PH. Lakin R, et al. Among authors: izaddoustdar f. Cardiovasc Res. 2023 Dec 19;119(16):2607-2622. doi: 10.1093/cvr/cvad144. Cardiovasc Res. 2023. PMID: 37713664
Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice.
Oh Y, Yang S, Liu X, Jana S, Izaddoustdar F, Gao X, Debi R, Kim DK, Kim KH, Yang P, Kassiri Z, Lakin R, Backx PH. Oh Y, et al. Among authors: izaddoustdar f. Front Physiol. 2020 Dec 23;11:605671. doi: 10.3389/fphys.2020.605671. eCollection 2020. Front Physiol. 2020. PMID: 33424629 Free PMC article.
Iron overload decreases CaV1.3-dependent L-type Ca2+ currents leading to bradycardia, altered electrical conduction, and atrial fibrillation.
Rose RA, Sellan M, Simpson JA, Izaddoustdar F, Cifelli C, Panama BK, Davis M, Zhao D, Markhani M, Murphy GG, Striessnig J, Liu PP, Heximer SP, Backx PH. Rose RA, et al. Among authors: izaddoustdar f. Circ Arrhythm Electrophysiol. 2011 Oct;4(5):733-42. doi: 10.1161/CIRCEP.110.960401. Epub 2011 Jul 11. Circ Arrhythm Electrophysiol. 2011. PMID: 21747058 Free PMC article.