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Clin Infect Dis. 2012 Jun;54(12):1778-83. doi: 10.1093/cid/cis307. Epub 2012 Mar 15.

Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine.

Author information

1
School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China. bcowling@hku.hk

Abstract

We randomized 115 children to trivalent inactivated influenza vaccine (TIV) or placebo. Over the following 9 months, TIV recipients had an increased risk of virologically-confirmed non-influenza infections (relative risk: 4.40; 95% confidence interval: 1.31-14.8). Being protected against influenza, TIV recipients may lack temporary non-specific immunity that protected against other respiratory viruses.

PMID:
22423139
PMCID:
PMC3404712
DOI:
10.1093/cid/cis307
[Indexed for MEDLINE]
Free PMC Article

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