Format
Sort by
Items per page

Send to

Choose Destination

Best matches for Importance of pregnenolone:

Search results

Items: 1 to 20 of 122

1.

The Modulating Role of Sex and Anabolic-Androgenic Steroid Hormones in Cannabinoid Sensitivity.

Struik D, Sanna F, Fattore L.

Front Behav Neurosci. 2018 Oct 26;12:249. doi: 10.3389/fnbeh.2018.00249. eCollection 2018. Review.

2.

Aberrant Splicing Is the Pathogenicity Mechanism of the p.Glu314Lys Variant in CYP11A1 Gene.

Goursaud C, Mallet D, Janin A, Menassa R, Tardy-Guidollet V, Russo G, Lienhardt-Roussie A, Lecointre C, Plotton I, Morel Y, Roucher-Boulez F.

Front Endocrinol (Lausanne). 2018 Sep 5;9:491. doi: 10.3389/fendo.2018.00491. eCollection 2018.

3.

Loss of Transient Receptor Potential Melastatin 3 ion channel function in natural killer cells from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients.

Cabanas H, Muraki K, Eaton N, Balinas C, Staines D, Marshall-Gradisnik S.

Mol Med. 2018 Aug 14;24(1):44. doi: 10.1186/s10020-018-0046-1.

4.

Protein Engineering of the Progesterone Hydroxylating P450-Monooxygenase CYP17A1 Alters Its Regioselectivity.

Morlock LK, Grobe S, Balke K, Mauersberger S, Böttcher D, Bornscheuer UT.

Chembiochem. 2018 Sep 17;19(18):1954-1958. doi: 10.1002/cbic.201800371. Epub 2018 Aug 7.

PMID:
29981252
5.

Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency.

Fernández-Cancio M, Camats N, Flück CE, Zalewski A, Dick B, Frey BM, Monné R, Torán N, Audí L, Pandey AV.

Pharmaceuticals (Basel). 2018 Apr 29;11(2). pii: E37. doi: 10.3390/ph11020037.

6.

Why pregnenolone and progesterone, two structurally similar steroids, exhibit remarkably different cocrystallization with aromatic molecules.

Luo Z, Friščić T, Khaliullin RZ.

Phys Chem Chem Phys. 2018 Jan 3;20(2):898-904. doi: 10.1039/c7cp06828j.

PMID:
29184919
7.

A Role of Endogenous Progesterone in Stroke Cerebroprotection Revealed by the Neural-Specific Deletion of Its Intracellular Receptors.

Zhu X, Fréchou M, Liere P, Zhang S, Pianos A, Fernandez N, Denier C, Mattern C, Schumacher M, Guennoun R.

J Neurosci. 2017 Nov 8;37(45):10998-11020. doi: 10.1523/JNEUROSCI.3874-16.2017. Epub 2017 Oct 6.

8.

Transcription factors SF1 and cJUN cooperate to activate the Fdx1 promoter in MA-10 Leydig cells.

Roumaud P, Rwigemera A, Martin LJ.

J Steroid Biochem Mol Biol. 2017 Jul;171:121-132. doi: 10.1016/j.jsbmb.2017.03.003. Epub 2017 Mar 6.

PMID:
28274746
9.

Long Residence Time at the Neurosteroidogenic 18 kDa Translocator Protein Characterizes the Anxiolytic Ligand XBD173.

Costa B, Da Pozzo E, Cavallini C, Taliani S, Da Settimo F, Martini C.

ACS Chem Neurosci. 2016 Aug 17;7(8):1041-6. doi: 10.1021/acschemneuro.6b00149. Epub 2016 Jul 8.

PMID:
27385308
10.

Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy.

Sarzi E, Seveno M, Angebault C, Milea D, Rönnbäck C, Quilès M, Adrian M, Grenier J, Caignard A, Lacroux A, Lavergne C, Reynier P, Larsen M, Hamel CP, Delettre C, Lenaers G, Müller A.

Hum Mol Genet. 2016 Jun 15;25(12):2539-2551. Epub 2016 Jun 3. Erratum in: Hum Mol Genet. 2017 Dec 1;26(23):4764.

PMID:
27260406
11.

Adrenal glands of Spix's yellow-toothed cavy (Galea spixii, Wagler, 1831): morphological and morphometric aspects.

Santos AC, Viana DC, Bertassoli BM, Vasconcelos BG, Oliveira DM, Rici RE, Oliveira MF, Miglino MA, Assis-Neto AC.

Braz J Biol. 2016 May 3;76(3):645-55. doi: 10.1590/1519-6984.23514.

12.

Regulation of the transient receptor potential channel TRPM3 by phosphoinositides.

Tóth BI, Konrad M, Ghosh D, Mohr F, Halaszovich CR, Leitner MG, Vriens J, Oberwinkler J, Voets T.

J Gen Physiol. 2015 Jul;146(1):51-63. doi: 10.1085/jgp.201411339.

13.

Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain.

Kutsuno Y, Hirashima R, Sakamoto M, Ushikubo H, Michimae H, Itoh T, Tukey RH, Fujiwara R.

Drug Metab Dispos. 2015 Jul;43(7):1071-6. doi: 10.1124/dmd.115.063719. Epub 2015 May 7.

14.

Novel activities of CYP11A1 and their potential physiological significance.

Slominski AT, Li W, Kim TK, Semak I, Wang J, Zjawiony JK, Tuckey RC.

J Steroid Biochem Mol Biol. 2015 Jul;151:25-37. doi: 10.1016/j.jsbmb.2014.11.010. Epub 2014 Nov 13. Review.

15.

A novel missense mutation in the HSD3B2 gene, underlying nonsalt-wasting congenital adrenal hyperplasia. new insight into the structure-function relationships of 3β-hydroxysteroid dehidrogenase type II.

Baquedano MS, Ciaccio M, Marino R, Perez Garrido N, Ramirez P, Maceiras M, Turjanski A, Defelipe LA, Rivarola MA, Belgorosky A.

J Clin Endocrinol Metab. 2015 Jan;100(1):E191-6. doi: 10.1210/jc.2014-2676.

PMID:
25322271
16.

Expression analysis of cyp11a1 during gonadal development, recrudescence and after hCG induction and sex steroid analog treatment in the catfish, Clarias batrachus.

Rajakumar A, Senthilkumaran B.

Comp Biochem Physiol B Biochem Mol Biol. 2014 Oct;176:42-7. doi: 10.1016/j.cbpb.2014.07.007. Epub 2014 Aug 7.

PMID:
25107325
17.

Assessment of pregnenolone effects on alcohol intake and preference in male alcohol preferring (P) rats.

Rezvani AH, Levin ED.

Eur J Pharmacol. 2014 Oct 5;740:53-7. doi: 10.1016/j.ejphar.2014.07.003. Epub 2014 Jul 10.

PMID:
25016089
18.

The environmental regulation of maturation in goldfish, Carassius auratus: effects of various LED light spectra.

Shin HS, Habibi HR, Choi CY.

Comp Biochem Physiol A Mol Integr Physiol. 2014 Feb;168:17-24. doi: 10.1016/j.cbpa.2013.11.003. Epub 2013 Nov 13.

PMID:
24239668
19.

Mitochondria and mammalian reproduction.

Ramalho-Santos J, Amaral S.

Mol Cell Endocrinol. 2013 Oct 15;379(1-2):74-84. doi: 10.1016/j.mce.2013.06.005. Epub 2013 Jun 13. Review.

PMID:
23769709
20.

CYP17A1: a biochemistry, chemistry, and clinical review.

Porubek D.

Curr Top Med Chem. 2013;13(12):1364-84. Review.

PMID:
23688130

Supplemental Content

Loading ...
Support Center