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J Heart Lung Transplant. 2018 May;37(5):548-563. doi: 10.1016/j.healun.2018.01.1309. Epub 2018 Feb 7.

ISHLT Consensus Statement on adult and pediatric airway complications after lung transplantation: Definitions, grading system, and therapeutics.

Author information

1
Division of Pulmonary, Allergy and Critical Care Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: maria.crespo@uphs.upenn.edu.
2
Division of Cardiothoracic Surgery, University of Wisconsin School of Medicine, Madison, Wisconsin.
3
Prince Charles Hospital, Brisbane, Queensland, Australia.
4
Cardiothoracic Division, Freeman Hospital, Newcastle, UK.
5
Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.
6
Division of Cardiothoracic Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
7
Department of Pulmonary Medicine, University Hospital of Zurich, Zurich, Switzerland.
8
Division of Pediatric Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, Missouri.
9
Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle, Washington.
10
Division of Pulmonary and Critical Care Medicine, University of California, San Francisco Medical Center, San Francisco, California.
11
Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
12
Division of Cardiothoracic Surgery, Advocate Christ Medical Center, Chicago, Illinois.
13
Division of Thoracic Surgery, Toronto General Hospital UHN, Toronto, Ontario, Canada.
14
Division of Pulmonary, Allergy and Critical Care Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
15
Division of Cardiothoracic Surgery, Yale University School of Medicine, New Haven, Connecticut.
16
Division of Pulmonary and Critical Care, The John Hopkins University Hospital, Baltimore, Maryland.
17
Department of Thoracic Surgery, Vienna Medical University, Vienna, Austria.
18
Department of Respiratory Diseases, University Hospital of Gasthuisberg, Leuven, Belgium.
19
Cardiothoracic Department, Sahlgrenska University Hospital, Göteborg, Sweden.
20
Division of Cardiothoracic Surgery, University of Washington, Seattle, Washington.

Abstract

Airway complications remain a major cause of morbidity and mortality after cardiothoracic transplantation. The reported incidence of airway ischemic complications varies widely, contributed to by the lack of a universally accepted grading system and standardized definitions. Furthermore, the majority of the existing classification systems fail to integrate the wide range of possible bronchial complications that may develop after lung transplant. Hence, a Working Group was created by the International Society for Heart and Lung Transplantation with the aim of elaborating a universal definition of adult and pediatric airway complications and grading system. One such area of focus is to understand the problem in the context of a more standardized consensus of classifying airway ischemia. This consensus definition will have major clinical, therapeutics, and research implications.

KEYWORDS:

airway complications; airway ischemia injury; anastomosis dehiscence; bronchial stenosis; lung transplantation

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