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Items: 1 to 20 of 190

1.

Retro Styles for Vesicle Coats.

Hurley JH, Johannes L.

Biochemistry. 2019 Jan 17. doi: 10.1021/acs.biochem.8b01271. [Epub ahead of print] No abstract available.

PMID:
30653311
2.

Bidirectional Control of Autophagy by BECN1 BARA Domain Dynamics.

Chang C, Young LN, Morris KL, von Bülow S, Schöneberg J, Yamamoto-Imoto H, Oe Y, Yamamoto K, Nakamura S, Stjepanovic G, Hummer G, Yoshimori T, Hurley JH.

Mol Cell. 2019 Jan 17;73(2):339-353.e6. doi: 10.1016/j.molcel.2018.10.035. Epub 2018 Dec 20.

PMID:
30581147
3.

ATP-dependent force generation and membrane scission by ESCRT-III and Vps4.

Schöneberg J, Pavlin MR, Yan S, Righini M, Lee IH, Carlson LA, Bahrami AH, Goldman DH, Ren X, Hummer G, Bustamante C, Hurley JH.

Science. 2018 Dec 21;362(6421):1423-1428. doi: 10.1126/science.aat1839.

PMID:
30573630
4.

Structural mechanism for HIV-1 TAR loop recognition by Tat and the super elongation complex.

Schulze-Gahmen U, Hurley JH.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):12973-12978. doi: 10.1073/pnas.1806438115. Epub 2018 Dec 4.

PMID:
30514815
5.

Inside job: how the ESCRTs release HIV-1 from infected cells.

Hurley JH, Cada AK.

Biochem Soc Trans. 2018 Oct 19;46(5):1029-1036. doi: 10.1042/BST20180019. Epub 2018 Aug 28. Review.

PMID:
30154094
6.

A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold.

Lawrence RE, Cho KF, Rappold R, Thrun A, Tofaute M, Kim DJ, Moldavski O, Hurley JH, Zoncu R.

Nat Cell Biol. 2018 Sep;20(9):1052-1063. doi: 10.1038/s41556-018-0148-6. Epub 2018 Jul 30.

PMID:
30061680
7.

HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.

Morris KL, Buffalo CZ, Stürzel CM, Heusinger E, Kirchhoff F, Ren X, Hurley JH.

Cell. 2018 Jul 26;174(3):659-671.e14. doi: 10.1016/j.cell.2018.07.004.

PMID:
30053425
8.

The dynamic Atg13-free conformation of the Atg1 EAT domain is required for phagophore expansion.

Lin MG, Schöneberg J, Davies CW, Ren X, Hurley JH.

Mol Biol Cell. 2018 May 15;29(10):1228-1237. doi: 10.1091/mbc.E17-04-0258. Epub 2018 Mar 22.

9.

The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading.

Gardner BM, Castanzo DT, Chowdhury S, Stjepanovic G, Stefely MS, Hurley JH, Lander GC, Martin A.

Nat Commun. 2018 Jan 10;9(1):135. doi: 10.1038/s41467-017-02474-4.

10.

Unveiling the role of VPS34 kinase domain dynamics in regulation of the autophagic PI3K complex.

Stjepanovic G, Baskaran S, Lin MG, Hurley JH.

Mol Cell Oncol. 2017 Sep 18;4(6):e1367873. doi: 10.1080/23723556.2017.1367873. eCollection 2017.

11.

Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex.

Su MY, Morris KL, Kim DJ, Fu Y, Lawrence R, Stjepanovic G, Zoncu R, Hurley JH.

Mol Cell. 2017 Dec 7;68(5):835-846.e3. doi: 10.1016/j.molcel.2017.10.016. Epub 2017 Nov 5.

12.

Scaffolding the cup-shaped double membrane in autophagy.

Bahrami AH, Lin MG, Ren X, Hurley JH, Hummer G.

PLoS Comput Biol. 2017 Oct 24;13(10):e1005817. doi: 10.1371/journal.pcbi.1005817. eCollection 2017 Oct.

13.

Vps34 Kinase Domain Dynamics Regulate the Autophagic PI 3-Kinase Complex.

Stjepanovic G, Baskaran S, Lin MG, Hurley JH.

Mol Cell. 2017 Aug 3;67(3):528-534.e3. doi: 10.1016/j.molcel.2017.07.003. Epub 2017 Jul 27.

14.

Friction at the BAR Leads to Membrane Breakup.

Mandadapu KK, Hurley JH.

Cell. 2017 Jun 29;170(1):14-16. doi: 10.1016/j.cell.2017.06.027.

15.

Mechanisms of Autophagy Initiation.

Hurley JH, Young LN.

Annu Rev Biochem. 2017 Jun 20;86:225-244. doi: 10.1146/annurev-biochem-061516-044820. Epub 2017 Mar 15. Review.

16.

Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription.

Qi S, Li Z, Schulze-Gahmen U, Stjepanovic G, Zhou Q, Hurley JH.

Nat Commun. 2017 Jan 30;8:14076. doi: 10.1038/ncomms14076.

17.

Molecular Mechanisms of Autophagy-Part B.

Tooze SA, Hurley JH.

J Mol Biol. 2017 Feb 17;429(4):455-456. doi: 10.1016/j.jmb.2017.01.009. Epub 2017 Jan 11. No abstract available.

PMID:
28087262
18.

Reverse-topology membrane scission by the ESCRT proteins.

Schöneberg J, Lee IH, Iwasa JH, Hurley JH.

Nat Rev Mol Cell Biol. 2017 Jan;18(1):5-17. doi: 10.1038/nrm.2016.121. Epub 2016 Oct 5. Review.

19.

Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.

Schulze-Gahmen U, Echeverria I, Stjepanovic G, Bai Y, Lu H, Schneidman-Duhovny D, Doudna JA, Zhou Q, Sali A, Hurley JH.

Elife. 2016 Oct 12;5. pii: e15910. doi: 10.7554/eLife.15910.

20.

Next-generation electron microscopy in autophagy research.

Hurley JH, Nogales E.

Curr Opin Struct Biol. 2016 Dec;41:211-216. doi: 10.1016/j.sbi.2016.08.006. Epub 2016 Sep 8. Review.

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