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Items: 1 to 20 of 228

1.

The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in C. elegans.

Davis GM, Tu S, Anderson JWT, Colson RN, Gunzburg MJ, Francisco MA, Ray D, Shrubsole SP, Sobotka JA, Seroussi U, Lao RX, Maity T, Wu MZ, McJunkin K, Morris QD, Hughes TR, Wilce JA, Claycomb JM, Weng Z, Boag PR.

Elife. 2018 Dec 21;7. pii: e35478. doi: 10.7554/eLife.35478. [Epub ahead of print]

2.

Functional analysis and fine mapping of the 9p22.2 ovarian cancer susceptibility locus.

Buckley MA, Woods NT, Tyrer JP, Mendoza-Fandiño G, Lawrenson K, Hazelett DJ, Najafabadi HS, Gjyshi A, Carvalho RS, Lyra PC, Coetzee SG, Shen HC, Yang AW, Earp MA, Yoder S, Risch H, Chenevix-Trench G, Ramus SJ, Phelan CM, Coetzee GA, Noushmehr H, Hughes TR, Sellers TA, Goode EL, Pharoah PDP, Gayther SA, Monteiro AN.

Cancer Res. 2018 Nov 28. pii: canres.3864.2017. doi: 10.1158/0008-5472.CAN-17-3864. [Epub ahead of print]

PMID:
30487138
3.

A physical and genetic map of Cannabis sativa identifies extensive rearrangements at the THC/CBD acid synthase loci.

Laverty KU, Stout JM, Sullivan MJ, Shah H, Gill N, Holbrook L, Deikus G, Sebra R, Hughes TR, Page JE, van Bakel H.

Genome Res. 2019 Jan;29(1):146-156. doi: 10.1101/gr.242594.118. Epub 2018 Nov 8.

4.

The Human Transcription Factors.

Lambert SA, Jolma A, Campitelli LF, Das PK, Yin Y, Albu M, Chen X, Taipale J, Hughes TR, Weirauch MT.

Cell. 2018 Oct 4;175(2):598-599. doi: 10.1016/j.cell.2018.09.045. No abstract available.

PMID:
30290144
5.

How bacterial xenogeneic silencer rok distinguishes foreign from self DNA in its resident genome.

Duan B, Ding P, Hughes TR, Navarre WW, Liu J, Xia B.

Nucleic Acids Res. 2018 Nov 2;46(19):10514-10529. doi: 10.1093/nar/gky836.

6.

Motif models for RNA-binding proteins.

Sasse A, Laverty KU, Hughes TR, Morris QD.

Curr Opin Struct Biol. 2018 Dec;53:115-123. doi: 10.1016/j.sbi.2018.08.001. Epub 2018 Aug 29. Review.

PMID:
30172081
7.

A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B).

François-Moutal L, Jahanbakhsh S, Nelson ADL, Ray D, Scott DD, Hennefarth MR, Moutal A, Perez-Miller S, Ambrose AJ, Al-Shamari A, Coursodon P, Meechoovet B, Reiman R, Lyons E, Beilstein M, Chapman E, Morris QD, Van Keuren-Jensen K, Hughes TR, Khanna R, Koehler C, Jen J, Gokhale V, Khanna M.

ACS Chem Biol. 2018 Oct 19;13(10):3000-3010. doi: 10.1021/acschembio.8b00745. Epub 2018 Sep 6.

PMID:
30141626
8.

Neurospora crassa developmental control mediated by the FLB-3 transcription factor.

Boni AC, Ambrósio DL, Cupertino FB, Montenegro-Montero A, Virgilio S, Freitas FZ, Corrocher FA, Gonçalves RD, Yang A, Weirauch MT, Hughes TR, Larrondo LF, Bertolini MC.

Fungal Biol. 2018 Jun;122(6):570-582. doi: 10.1016/j.funbio.2018.01.004. Epub 2018 Mar 1.

PMID:
29801802
9.

Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.

Liu K, Xu C, Lei M, Yang A, Loppnau P, Hughes TR, Min J.

J Biol Chem. 2018 May 11;293(19):7344-7354. doi: 10.1074/jbc.RA118.001785. Epub 2018 Mar 22.

PMID:
29567833
10.

The Human Transcription Factors.

Lambert SA, Jolma A, Campitelli LF, Das PK, Yin Y, Albu M, Chen X, Taipale J, Hughes TR, Weirauch MT.

Cell. 2018 Feb 8;172(4):650-665. doi: 10.1016/j.cell.2018.01.029. Review. Erratum in: Cell. 2018 Oct 4;175(2):598-599.

PMID:
29425488
11.

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

Xu C, Liu K, Lei M, Yang A, Li Y, Hughes TR, Min J.

Structure. 2018 Jan 2;26(1):85-95.e3. doi: 10.1016/j.str.2017.11.022. Epub 2017 Dec 21.

12.

The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor.

Townsend PD, Dixon CH, Slootweg EJ, Sukarta OCA, Yang AWH, Hughes TR, Sharples GJ, Pålsson LO, Takken FLW, Goverse A, Cann MJ.

J Biol Chem. 2018 Mar 2;293(9):3218-3233. doi: 10.1074/jbc.RA117.000485. Epub 2017 Dec 7.

13.

Absence of CD59 in Guinea Pigs: Analysis of the Cavia porcellus Genome Suggests the Evolution of a CD59 Pseudogene.

Boshra H, Zelek WM, Hughes TR, Rodriguez de Cordoba S, Morgan BP.

J Immunol. 2018 Jan 1;200(1):327-335. doi: 10.4049/jimmunol.1701238. Epub 2017 Nov 22.

14.

Comparison of ChIP-Seq Data and a Reference Motif Set for Human KRAB C2H2 Zinc Finger Proteins.

Barazandeh M, Lambert SA, Albu M, Hughes TR.

G3 (Bethesda). 2018 Jan 4;8(1):219-229. doi: 10.1534/g3.117.300296.

15.

Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding.

Najafabadi HS, Garton M, Weirauch MT, Mnaimneh S, Yang A, Kim PM, Hughes TR.

Genome Biol. 2017 Sep 6;18(1):167. doi: 10.1186/s13059-017-1287-y.

16.

Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma.

Dang H, Takai A, Forgues M, Pomyen Y, Mou H, Xue W, Ray D, Ha KCH, Morris QD, Hughes TR, Wang XW.

Cancer Cell. 2017 Jul 10;32(1):101-114.e8. doi: 10.1016/j.ccell.2017.06.002.

17.

RNAcompete-S: Combined RNA sequence/structure preferences for RNA binding proteins derived from a single-step in vitro selection.

Cook KB, Vembu S, Ha KCH, Zheng H, Laverty KU, Hughes TR, Ray D, Morris QD.

Methods. 2017 Aug 15;126:18-28. doi: 10.1016/j.ymeth.2017.06.024. Epub 2017 Jun 24.

PMID:
28651966
18.

The anti-cholesterolaemic effect of a consortium of probiotics: An acute study in C57BL/6J mice.

Michael DR, Davies TS, Moss JWE, Calvente DL, Ramji DP, Marchesi JR, Pechlivanis A, Plummer SF, Hughes TR.

Sci Rep. 2017 Jun 6;7(1):2883. doi: 10.1038/s41598-017-02889-5.

19.

Direct Binding of the pH-Regulated Protein 1 (Pra1) from Candida albicans Inhibits Cytokine Secretion by Mouse CD4+ T Cells.

Bergfeld A, Dasari P, Werner S, Hughes TR, Song WC, Hortschansky P, Brakhage AA, Hünig T, Zipfel PF, Beyersdorf N.

Front Microbiol. 2017 May 11;8:844. doi: 10.3389/fmicb.2017.00844. eCollection 2017.

20.

Transcription factors read epigenetics.

Hughes TR, Lambert SA.

Science. 2017 May 5;356(6337):489-490. doi: 10.1126/science.aan2927. No abstract available.

PMID:
28473550

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