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The Calcium Channel Blocker Bepridil Demonstrates Efficacy in the Murine Model of Marburg Virus Disease.

DeWald LE, Dyall J, Sword JM, Torzewski L, Zhou H, Postnikova E, Kollins E, Alexander I, Gross R, Cong Y, Gerhardt DM, Johnson RF, Olinger GG Jr, Holbrook MR, Hensley LE, Jahrling PB.

J Infect Dis. 2018 Jul 4. doi: 10.1093/infdis/jiy332. [Epub ahead of print]


Will a single-cycle Adenovirus vaccine be effective against Ebola virus?

Holbrook MR.

J Infect Dis. 2018 Jul 6. doi: 10.1093/infdis/jiy412. [Epub ahead of print] No abstract available.


Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures.

Dyall J, Nelson EA, DeWald LE, Guha R, Hart BJ, Zhou H, Postnikova E, Logue J, Vargas WM, Gross R, Michelotti J, Deiuliis N, Bennett RS, Crozier I, Holbrook MR, Morris PJ, Klumpp-Thomas C, McKnight C, Mierzwa T, Shinn P, Glass PJ, Johansen LM, Jahrling PB, Hensley LE, Olinger GG Jr, Thomas C, White JM.

J Infect Dis. 2018 Jun 25. doi: 10.1093/infdis/jiy304. [Epub ahead of print]


Development of a novel real-time polymerase chain reaction assay for the quantitative detection of Nipah virus replicative viral RNA.

Jensen KS, Adams R, Bennett RS, Bernbaum J, Jahrling PB, Holbrook MR.

PLoS One. 2018 Jun 19;13(6):e0199534. doi: 10.1371/journal.pone.0199534. eCollection 2018.


Flavorings in Tobacco Products Induce Endothelial Cell Dysfunction.

Fetterman JL, Weisbrod RM, Feng B, Bastin R, Tuttle ST, Holbrook M, Baker G, Robertson RM, Conklin DJ, Bhatnagar A, Hamburg NM.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1607-1615. doi: 10.1161/ATVBAHA.118.311156. Epub 2018 Jun 14.


Rapid on-site evaluation facilitated the diagnosis of a rare case of Talaromyces marneffei infection.

Ma W, Thiryayi SA, Holbrook M, Shelton D, Narine N, Sweeney LC, Augustine T, Bailey S, Al-Najjar H, Rana DN.

Cytopathology. 2018 Oct;29(5):497-499. doi: 10.1111/cyt.12563. Epub 2018 Jun 12. No abstract available.


Protocol to assess the impact of tobacco-induced volatile organic compounds on cardiovascular risk in a cross- sectional cohort: Cardiovascular Injury due to Tobacco Use study.

Keith RJ, Fetterman JL, Riggs DW, O'Toole T, Nystoriak JL, Holbrook M, Lorkiewicz P, Bhatnagar A, DeFilippis AP, Hamburg NM.

BMJ Open. 2018 Mar 30;8(3):e019850. doi: 10.1136/bmjopen-2017-019850.


Testing therapeutics in cell-based assays: Factors that influence the apparent potency of drugs.

Postnikova E, Cong Y, DeWald LE, Dyall J, Yu S, Hart BJ, Zhou H, Gross R, Logue J, Cai Y, Deiuliis N, Michelotti J, Honko AN, Bennett RS, Holbrook MR, Olinger GG, Hensley LE, Jahrling PB.

PLoS One. 2018 Mar 22;13(3):e0194880. doi: 10.1371/journal.pone.0194880. eCollection 2018.


MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells.

Cong Y, Hart BJ, Gross R, Zhou H, Frieman M, Bollinger L, Wada J, Hensley LE, Jahrling PB, Dyall J, Holbrook MR.

PLoS One. 2018 Mar 22;13(3):e0194868. doi: 10.1371/journal.pone.0194868. eCollection 2018.


Ebola Virus Localization in the Macaque Reproductive Tract during Acute Ebola Virus Disease.

Perry DL, Huzella LM, Bernbaum JG, Holbrook MR, Jahrling PB, Hagen KR, Schnell MJ, Johnson RF.

Am J Pathol. 2018 Mar;188(3):550-558. doi: 10.1016/j.ajpath.2017.11.004. Epub 2018 Feb 14.


A mixed-method evaluation of the New York State Eat Well Play Hard Community Projects: Building local capacity for sustainable childhood obesity prevention.

Reid KS, Sekhobo JP, Gantner LA, Holbrook MK, Allsopp M, Whalen LB, Koren-Roth A.

Eval Program Plann. 2018 Apr;67:79-88. doi: 10.1016/j.evalprogplan.2017.12.004. Epub 2017 Dec 9.


A VLP-based vaccine provides complete protection against Nipah virus challenge following multiple-dose or single-dose vaccination schedules in a hamster model.

Walpita P, Cong Y, Jahrling PB, Rojas O, Postnikova E, Yu S, Johns L, Holbrook MR.

NPJ Vaccines. 2017 Aug 8;2:21. doi: 10.1038/s41541-017-0023-7. eCollection 2017.


Cross-neutralisation of viruses of the tick-borne encephalitis complex following tick-borne encephalitis vaccination and/or infection.

McAuley AJ, Sawatsky B, Ksiazek T, Torres M, Korva M, Lotrič-Furlan S, Avšič-Županc T, von Messling V, Holbrook MR, Freiberg AN, Beasley DWC, Bente DA.

NPJ Vaccines. 2017 Mar 13;2:5. doi: 10.1038/s41541-017-0009-5. eCollection 2017.


Outcomes of endoscopic ultrasound-guided pancreatic FNAC diagnosis for solid and cystic lesions at Manchester Royal Infirmary based upon the Papanicolaou Society of Cytopathology pancreaticobiliary terminology classification scheme.

Wright PK, Shelton DA, Holbrook MR, Thiryayi SA, Narine N, Slater D, Rana DN.

Cytopathology. 2018 Feb;29(1):71-79. doi: 10.1111/cyt.12502. Epub 2017 Nov 29.


Low-dose 4D cardiac imaging in small animals using dual source micro-CT.

Holbrook M, Clark DP, Badea CT.

Phys Med Biol. 2018 Jan 9;63(2):025009. doi: 10.1088/1361-6560/aa9b45.


Effects of opioid medications on cognitive skills among Emergency Department patients.

Marco CA, Mann D, Rasp J, Ballester M, Perkins O, Holbrook MB, Rako K.

Am J Emerg Med. 2018 Jun;36(6):1009-1013. doi: 10.1016/j.ajem.2017.11.017. Epub 2017 Nov 8.


Advance directives in emergency medicine: Patient perspectives and application to clinical scenarios.

Marco CA, Mozeleski E, Mann D, Holbrook MB, Serpico MR, Holyoke A, Ginting K, Ahmed A.

Am J Emerg Med. 2018 Mar;36(3):516-518. doi: 10.1016/j.ajem.2017.08.002. Epub 2017 Aug 2. No abstract available.


Dual-wavelength reflectance spectroscopy of the superior vena cava: A method for placing central venous catheters at the cavoatrial junction.

Stringer BJ, Shumway SB, Holbrook MD, Copeland CG, Gosch AA, Kück K.

J Biophotonics. 2018 Apr;11(4):e201700018. doi: 10.1002/jbio.201700018. Epub 2017 Dec 12.


Historical Perspectives on Flavivirus Research.

Holbrook MR.

Viruses. 2017 Apr 30;9(5). pii: E97. doi: 10.3390/v9050097. Review.


Loss in lung volume and changes in the immune response demonstrate disease progression in African green monkeys infected by small-particle aerosol and intratracheal exposure to Nipah virus.

Cong Y, Lentz MR, Lara A, Alexander I, Bartos C, Bohannon JK, Hammoud D, Huzella L, Jahrling PB, Janosko K, Jett C, Kollins E, Lackemeyer M, Mollura D, Ragland D, Rojas O, Solomon J, Xu Z, Munster V, Holbrook MR.

PLoS Negl Trop Dis. 2017 Apr 7;11(4):e0005532. doi: 10.1371/journal.pntd.0005532. eCollection 2017 Apr.

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