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Items: 1 to 20 of 23

1.

Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point.

Veverka P, Janovič T, Hofr C.

Int J Mol Sci. 2019 Jun 28;20(13). pii: E3186. doi: 10.3390/ijms20133186. Review.

2.

Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 when TPP1 Is Absent.

Janovič T, Stojaspal M, Veverka P, Horáková D, Hofr C.

J Mol Biol. 2019 Aug 9;431(17):3289-3301. doi: 10.1016/j.jmb.2019.05.038. Epub 2019 May 31.

3.

Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it.

Necasová I, Janoušková E, Klumpler T, Hofr C.

Nucleic Acids Res. 2017 Dec 1;45(21):12599. doi: 10.1093/nar/gkx968. No abstract available.

4.

Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it.

Necasová I, Janoušková E, Klumpler T, Hofr C.

Nucleic Acids Res. 2017 Dec 1;45(21):12170-12180. doi: 10.1093/nar/gkx812.

5.

Protection of Arabidopsis Blunt-Ended Telomeres Is Mediated by a Physical Association with the Ku Heterodimer.

Valuchova S, Fulnecek J, Prokop Z, Stolt-Bergner P, Janouskova E, Hofr C, Riha K.

Plant Cell. 2017 Jun;29(6):1533-1545. doi: 10.1105/tpc.17.00064. Epub 2017 Jun 5.

6.

Evolution of Telomeres in Schizosaccharomyces pombe and Its Possible Relationship to the Diversification of Telomere Binding Proteins.

Sepsiova R, Necasova I, Willcox S, Prochazkova K, Gorilak P, Nosek J, Hofr C, Griffith JD, Tomaska L.

PLoS One. 2016 Apr 21;11(4):e0154225. doi: 10.1371/journal.pone.0154225. eCollection 2016.

7.

Human Rap1 modulates TRF2 attraction to telomeric DNA.

Janoušková E, Nečasová I, Pavloušková J, Zimmermann M, Hluchý M, Marini V, Nováková M, Hofr C.

Nucleic Acids Res. 2015 Mar 11;43(5):2691-700. doi: 10.1093/nar/gkv097. Epub 2015 Feb 11.

8.

Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.

Dalby AB, Hofr C, Cech TR.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1291-1303. doi: 10.1016/j.jmb.2015.01.008. Epub 2015 Jan 23.

9.

New PAH derivatives functionalized by cyclic nitrone framework: synthetic design, anti-proliferative activity and interaction with DNA.

Buchlovič M, Kříž Z, Hofr C, Potáček M.

Bioorg Med Chem. 2013 Mar 1;21(5):1078-81. doi: 10.1016/j.bmc.2013.01.004. Epub 2013 Jan 11.

PMID:
23352483
10.

Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1.

Kubicek K, Cerna H, Holub P, Pasulka J, Hrossova D, Loehr F, Hofr C, Vanacova S, Stefl R.

Genes Dev. 2012 Sep 1;26(17):1891-6. doi: 10.1101/gad.192781.112. Epub 2012 Aug 14.

11.

Synergism of the two Myb domains of Tay1 protein results in high affinity binding to telomeres.

Visacka K, Hofr C, Willcox S, Necasova I, Pavlouskova J, Sepsiova R, Wimmerova M, Simonicova L, Nosek J, Fajkus J, Griffith JD, Tomaska L.

J Biol Chem. 2012 Sep 14;287(38):32206-15. doi: 10.1074/jbc.M112.385591. Epub 2012 Jul 18.

12.

Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (NAB) 3 protein.

Hobor F, Pergoli R, Kubicek K, Hrossova D, Bacikova V, Zimmermann M, Pasulka J, Hofr C, Vanacova S, Stefl R.

J Biol Chem. 2011 Feb 4;286(5):3645-57. doi: 10.1074/jbc.M110.158774. Epub 2010 Nov 17.

13.

The solution structure of the ADAR2 dsRBM-RNA complex reveals a sequence-specific readout of the minor groove.

Stefl R, Oberstrass FC, Hood JL, Jourdan M, Zimmermann M, Skrisovska L, Maris C, Peng L, Hofr C, Emeson RB, Allain FH.

Cell. 2010 Oct 15;143(2):225-37. doi: 10.1016/j.cell.2010.09.026.

14.

Single-Myb-histone proteins from Arabidopsis thaliana: a quantitative study of telomere-binding specificity and kinetics.

Hofr C, Sultesová P, Zimmermann M, Mozgová I, Procházková Schrumpfová P, Wimmerová M, Fajkus J.

Biochem J. 2009 Apr 1;419(1):221-8, 2 p following 228. doi: 10.1042/BJ20082195.

PMID:
19102728
15.

Functional characterization of domains in AtTRB1, a putative telomere-binding protein in Arabidopsis thaliana.

Mozgová I, Schrumpfová PP, Hofr C, Fajkus J.

Phytochemistry. 2008 Jun;69(9):1814-9. doi: 10.1016/j.phytochem.2008.04.001. Epub 2008 May 12.

PMID:
18479720
16.
17.

Conformation of DNA modified by monofunctional Ru(II) arene complexes: recognition by DNA binding proteins and repair. Relationship to cytotoxicity.

Novakova O, Kasparkova J, Bursova V, Hofr C, Vojtiskova M, Chen H, Sadler PJ, Brabec V.

Chem Biol. 2005 Jan;12(1):121-9.

18.

Effects of monofunctional adducts of platinum(II) complexes on thermodynamic stability and energetics of DNA duplexes.

Bursova V, Kasparkova J, Hofr C, Brabec V.

Biophys J. 2005 Feb;88(2):1207-14. Epub 2004 Dec 1.

19.

High affinity fucose binding of Pseudomonas aeruginosa lectin PA-IIL: 1.0 A resolution crystal structure of the complex combined with thermodynamics and computational chemistry approaches.

Mitchell EP, Sabin C, Snajdrová L, Pokorná M, Perret S, Gautier C, Hofr C, Gilboa-Garber N, Koca J, Wimmerová M, Imberty A.

Proteins. 2005 Feb 15;58(3):735-46.

PMID:
15573375

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