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TPO-logy accepted.

Hoffmeister KM.

Blood. 2018 Aug 9;132(6):555-557. doi: 10.1182/blood-2018-06-854935. No abstract available.


Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets.

Chen W, Druzak SA, Wang Y, Josephson CD, Hoffmeister KM, Ware J, Li R.

Arterioscler Thromb Vasc Biol. 2017 Dec;37(12):2271-2279. doi: 10.1161/ATVBAHA.117.310062. Epub 2017 Nov 2.


Circulating blood and platelets supply glycosyltransferases that enable extrinsic extracellular glycosylation.

Lee-Sundlov MM, Ashline DJ, Hanneman AJ, Grozovsky R, Reinhold VN, Hoffmeister KM, Lau JT.

Glycobiology. 2017 Jan;27(2):188-198. doi: 10.1093/glycob/cww108. Epub 2016 Oct 26.


Platelet clearance by the hepatic Ashwell-Morrell receptor: mechanisms and biological significance.

Hoffmeister KM, Falet H.

Thromb Res. 2016 May;141 Suppl 2:S68-72. doi: 10.1016/S0049-3848(16)30370-X. Review.


Glycans and the platelet life cycle.

Li R, Hoffmeister KM, Falet H.

Platelets. 2016 Sep;27(6):505-11. doi: 10.3109/09537104.2016.1171304. Epub 2016 May 2. Review.


Regulating billions of blood platelets: glycans and beyond.

Grozovsky R, Giannini S, Falet H, Hoffmeister KM.

Blood. 2015 Oct 15;126(16):1877-84. doi: 10.1182/blood-2015-01-569129. Epub 2015 Sep 1. Review.


2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium.

Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S; State of the Science in Transfusion Medicine Working Groups.

Transfusion. 2015 Sep;55(9):2282-90. doi: 10.1111/trf.13250. Epub 2015 Aug 10.


Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia.

Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, Zhu L, Zeng Q, Tao L, Zhai ZM, Peng J, Hou M, Leytin V, Freedman J, Hoffmeister KM, Ni H.

Nat Commun. 2015 Jul 17;6:7737. doi: 10.1038/ncomms8737.


Novel mechanisms of platelet clearance and thrombopoietin regulation.

Grozovsky R, Giannini S, Falet H, Hoffmeister KM.

Curr Opin Hematol. 2015 Sep;22(5):445-51. doi: 10.1097/MOH.0000000000000170. Review.


FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.

Begonja AJ, Pluthero FG, Suphamungmee W, Giannini S, Christensen H, Leung R, Lo RW, Nakamura F, Lehman W, Plomann M, Hoffmeister KM, Kahr WH, Hartwig JH, Falet H.

Blood. 2015 Jul 2;126(1):80-8. doi: 10.1182/blood-2014-07-587600. Epub 2015 Apr 2.


The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling.

Grozovsky R, Begonja AJ, Liu K, Visner G, Hartwig JH, Falet H, Hoffmeister KM.

Nat Med. 2015 Jan;21(1):47-54. doi: 10.1038/nm.3770. Epub 2014 Dec 8.


Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice.

Bender M, Giannini S, Grozovsky R, Jönsson T, Christensen H, Pluthero FG, Ko A, Mullally A, Kahr WH, Hoffmeister KM, Falet H.

Blood. 2015 Feb 5;125(6):1014-24. doi: 10.1182/blood-2014-07-587857. Epub 2014 Dec 2.


Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan.

Liu ZJ, Hoffmeister KM, Hu Z, Mager DE, Ait-Oudhia S, Debrincat MA, Pleines I, Josefsson EC, Kile BT, Italiano J Jr, Ramsey H, Grozovsky R, Veng-Pedersen P, Chavda C, Sola-Visner M.

Blood. 2014 May 29;123(22):3381-9. doi: 10.1182/blood-2013-06-508200. Epub 2014 Mar 5.


Wiskott-Aldrich syndrome protein (WASp) controls the delivery of platelet transforming growth factor-β1.

Kim H, Falet H, Hoffmeister KM, Hartwig JH.

J Biol Chem. 2013 Nov 29;288(48):34352-63. doi: 10.1074/jbc.M113.459750. Epub 2013 Oct 16.


Death regulates platelet birth and life.

Hoffmeister KM.

Blood. 2012 Jun 14;119(24):5617-8. doi: 10.1182/blood-2012-04-417295. No abstract available.


The origin and function of platelet glycosyltransferases.

Wandall HH, Rumjantseva V, Sørensen AL, Patel-Hett S, Josefsson EC, Bennett EP, Italiano JE Jr, Clausen H, Hartwig JH, Hoffmeister KM.

Blood. 2012 Jul 19;120(3):626-35. doi: 10.1182/blood-2012-02-409235. Epub 2012 May 21.


Polymorphism in the protease-activated receptor-4 gene region associates with platelet activation and perioperative myocardial injury.

Muehlschlegel JD, Perry TE, Liu KY, Fox AA, Smith SA, Lichtner P, Collard CD, Shernan SK, Hartwig JH, Body SC, Hoffmeister KM.

Am J Hematol. 2012 Feb;87(2):161-6. doi: 10.1002/ajh.22244. Epub 2012 Jan 7.


Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.

Jansen AJ, Josefsson EC, Rumjantseva V, Liu QP, Falet H, Bergmeier W, Cifuni SM, Sackstein R, von Andrian UH, Wagner DD, Hartwig JH, Hoffmeister KM.

Blood. 2012 Feb 2;119(5):1263-73. doi: 10.1182/blood-2011-05-355628. Epub 2011 Nov 18.


The role of lectins and glycans in platelet clearance.

Hoffmeister KM.

J Thromb Haemost. 2011 Jul;9 Suppl 1:35-43. doi: 10.1111/j.1538-7836.2011.04276.x. Review.


FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly.

Jurak Begonja A, Hoffmeister KM, Hartwig JH, Falet H.

Blood. 2011 Aug 25;118(8):2285-95. doi: 10.1182/blood-2011-04-348482. Epub 2011 Jun 7.

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