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Items: 1 to 20 of 132


Mathematical Modeling of Tumor-Tumor Distant Interactions Supports a Systemic Control of Tumor Growth.

Benzekry S, Lamont C, Barbolosi D, Hlatky L, Hahnfeldt P.

Cancer Res. 2017 Sep 15;77(18):5183-5193. doi: 10.1158/0008-5472.CAN-17-0564. Epub 2017 Jul 20.


Host mediated inflammatory influence on glioblastoma multiforme recurrence following high-dose ionizing radiation.

McDonald JT, Gao X, Steber C, Lee Breed J, Pollock C, Ma L, Hlatky L.

PLoS One. 2017 May 22;12(5):e0178155. doi: 10.1371/journal.pone.0178155. eCollection 2017.


Capturing the Driving Role of Tumor-Host Crosstalk in a Dynamical Model of Tumor Growth.

Benzekry S, Beheshti A, Hahnfeldt P, Hlatky L.

Bio Protoc. 2015 Nov 5;5(21). pii: e1644.


Radiation-Induced Reprogramming of Pre-Senescent Mammary Epithelial Cells Enriches Putative CD44(+)/CD24(-/low) Stem Cell Phenotype.

Gao X, Sishc BJ, Nelson CB, Hahnfeldt P, Bailey SM, Hlatky L.

Front Oncol. 2016 Jun 14;6:138. doi: 10.3389/fonc.2016.00138. eCollection 2016.


Therapeutic Effectiveness of Anticancer Phytochemicals on Cancer Stem Cells.

Oh J, Hlatky L, Jeong YS, Kim D.

Toxins (Basel). 2016 Jun 30;8(7). pii: E199. doi: 10.3390/toxins8070199. Review.


Evaluating biomarkers to model cancer risk post cosmic ray exposure.

Sridharan DM, Asaithamby A, Blattnig SR, Costes SV, Doetsch PW, Dynan WS, Hahnfeldt P, Hlatky L, Kidane Y, Kronenberg A, Naidu MD, Peterson LE, Plante I, Ponomarev AL, Saha J, Snijders AM, Srinivasan K, Tang J, Werner E, Pluth JM.

Life Sci Space Res (Amst). 2016 Jun;9:19-47. doi: 10.1016/j.lssr.2016.05.004. Epub 2016 May 21. Review.


Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma.

Ravi D, Beheshti A, Abermil N, Passero F, Sharma J, Coyle M, Kritharis A, Kandela I, Hlatky L, Sitkovsky MV, Mazar A, Gartenhaus RB, Evens AM.

Cancer Res. 2016 Jun 1;76(11):3319-31. doi: 10.1158/0008-5472.CAN-15-2477. Epub 2016 Mar 17.


Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development.

Beheshti A, Wage J, McDonald JT, Lamont C, Peluso M, Hahnfeldt P, Hlatky L.

Oncotarget. 2015 Nov 3;6(34):35419-32. doi: 10.18632/oncotarget.6214.


Concepts and challenges in cancer risk prediction for the space radiation environment.

Barcellos-Hoff MH, Blakely EA, Burma S, Fornace AJ Jr, Gerson S, Hlatky L, Kirsch DG, Luderer U, Shay J, Wang Y, Weil MM.

Life Sci Space Res (Amst). 2015 Jul;6:92-103. doi: 10.1016/j.lssr.2015.07.006. Epub 2015 Jul 17. Review.


Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue.

Wage J, Ma L, Peluso M, Lamont C, Evens AM, Hahnfeldt P, Hlatky L, Beheshti A.

J Radiat Res. 2015 Sep;56(5):792-803. doi: 10.1093/jrr/rrv043. Epub 2015 Aug 7.


Fractionated Radiation Exposure of Rat Spinal Cords Leads to Latent Neuro-Inflammation in Brain, Cognitive Deficits, and Alterations in Apurinic Endonuclease 1.

Suresh Kumar MA, Peluso M, Chaudhary P, Dhawan J, Beheshti A, Manickam K, Thapar U, Pena L, Natarajan M, Hlatky L, Demple B, Naidu M.

PLoS One. 2015 Jul 24;10(7):e0133016. doi: 10.1371/journal.pone.0133016. eCollection 2015.


Biological effects of proton radiation: an update.

Girdhani S, Sachs R, Hlatky L.

Radiat Prot Dosimetry. 2015 Sep;166(1-4):334-8. doi: 10.1093/rpd/ncv178. Epub 2015 Apr 20.


Host age is a systemic regulator of gene expression impacting cancer progression.

Beheshti A, Benzekry S, McDonald JT, Ma L, Peluso M, Hahnfeldt P, Hlatky L.

Cancer Res. 2015 Mar 15;75(6):1134-43. doi: 10.1158/0008-5472.CAN-14-1053. Epub 2015 Mar 2.


Stochastic process pharmacodynamics: dose timing in neonatal gentamicin therapy as an example.

Radivoyevitch T, Siranart N, Hlatky L, Sachs R.

AAPS J. 2015 Mar;17(2):447-56. doi: 10.1208/s12248-014-9715-3. Epub 2015 Feb 7.


Distinct luminal-type mammary carcinomas arise from orthotopic Trp53-null mammary transplantation of juvenile versus adult mice.

Nguyen DH, Ouyang H, Mao JH, Hlatky L, Barcellos-Hoff MH.

Cancer Res. 2014 Dec 1;74(23):7149-58. doi: 10.1158/0008-5472.CAN-14-1440. Epub 2014 Oct 3.


Why is there so much therapy-related AML and MDS and so little therapy-related CML?

Gale RP, Hlatky L, Sachs RK, Radivoyevitch T.

Leuk Res. 2014 Oct;38(10):1162-4. doi: 10.1016/j.leukres.2014.08.002. Epub 2014 Aug 11. No abstract available.


Classical mathematical models for description and prediction of experimental tumor growth.

Benzekry S, Lamont C, Beheshti A, Tracz A, Ebos JM, Hlatky L, Hahnfeldt P.

PLoS Comput Biol. 2014 Aug 28;10(8):e1003800. doi: 10.1371/journal.pcbi.1003800. eCollection 2014 Aug.


A proposed quantitative index for assessing the potential contribution of reprogramming to cancer stem cell kinetics.

Gao X, McDonald JT, Naidu M, Hahnfeldt P, Hlatky L.

Stem Cells Int. 2014;2014:249309. doi: 10.1155/2014/249309. Epub 2014 May 12.


A multicompartment mathematical model of cancer stem cell-driven tumor growth dynamics.

Weekes SL, Barker B, Bober S, Cisneros K, Cline J, Thompson A, Hlatky L, Hahnfeldt P, Enderling H.

Bull Math Biol. 2014 Jul;76(7):1762-82. doi: 10.1007/s11538-014-9976-0. Epub 2014 May 20.


Proton irradiation augments the suppression of tumor progression observed with advanced age.

Beheshti A, Peluso M, Lamont C, Hahnfeldt P, Hlatky L.

Radiat Res. 2014 Mar;181(3):272-83. doi: 10.1667/RR13538.1. Epub 2014 Feb 25.

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