Hiroyama S[Author] - Search Results

Year	Number of Results
2007	1
2008	1
2010	1
2012	1
2018	3
2020	1
2022	1
2023	1
2024	1

1

Usefulness of ¹⁸F-FPP-RGD₂ PET in pathophysiological evaluation of lung fibrosis using a bleomycin-induced rat model.

Hiroyama S, Matsunaga K, Ito M, Iimori H, Tajiri M, Nakano Y, Shimosegawa E, Abe K. Hiroyama S, et al. Eur J Nucl Med Mol Imaging. 2022 Nov;49(13):4358-4368. doi: 10.1007/s00259-022-05908-4. Epub 2022 Jul 25. Eur J Nucl Med Mol Imaging. 2022. PMID: 35876866

2

Evaluation of an Integrin α_vβ₃ Radiotracer, [¹⁸F]F-FPP-RGD₂, for Monitoring Pharmacological Effects of Integrin α_v siRNA in the NASH Liver.

Hiroyama S, Matsunaga K, Ito M, Iimori H, Morita I, Nakamura J, Shimosegawa E, Abe K. Hiroyama S, et al. Nucl Med Mol Imaging. 2023 Aug;57(4):172-179. doi: 10.1007/s13139-023-00791-9. Epub 2023 Mar 7. Nucl Med Mol Imaging. 2023. PMID: 37483876

3

Semi-Automated Biomarker Discovery from Pharmacodynamic Effects on EEG in ADHD Rodent Models.

Yokota T, Struzik ZR, Jurica P, Horiuchi M, Hiroyama S, Li J, Takahara Y, Ogawa K, Nishitomi K, Hasegawa M, Cichocki A. Yokota T, et al. Among authors: hiroyama s. Sci Rep. 2018 Mar 26;8(1):5202. doi: 10.1038/s41598-018-23450-y. Sci Rep. 2018. PMID: 29581452 Free PMC article.

4

The nociceptin/orphanin FQ receptor partial agonist sunobinop promotes non-REM sleep in rodents and patients with insomnia.

Whiteside GT, Kyle DJ, Kapil RP, Cipriano A, He E, Zhou M, Shet MS, Hummel M, Knappenberger T, Fukumura K, Matsuo Y, Uehira M, Hiroyama S, Takai N, Willsie SK, Harris SC. Whiteside GT, et al. Among authors: hiroyama s. J Clin Invest. 2024 Jan 2;134(1):e171172. doi: 10.1172/JCI171172. J Clin Invest. 2024. PMID: 37883189 Free PMC article.

5

S-nitrosylated human serum albumin-mediated cytoprotective activity is enhanced by fatty acid binding.

Ishima Y, Akaike T, Kragh-Hansen U, Hiroyama S, Sawa T, Suenaga A, Maruyama T, Kai T, Otagiri M. Ishima Y, et al. Among authors: hiroyama s. J Biol Chem. 2008 Dec 12;283(50):34966-75. doi: 10.1074/jbc.M807009200. Epub 2008 Oct 20. J Biol Chem. 2008. PMID: 18940810 Free PMC article.

6

One-step preparation of S-nitrosated human serum albumin with high biological activities.

Ishima Y, Hiroyama S, Kragh-Hansen U, Maruyama T, Sawa T, Akaike T, Kai T, Otagiri M. Ishima Y, et al. Among authors: hiroyama s. Nitric Oxide. 2010 Sep 15;23(2):121-7. doi: 10.1016/j.niox.2010.05.002. Epub 2010 May 6. Nitric Oxide. 2010. PMID: 20451647

7

Combining behavior and EEG analysis for exploration of dynamic effects of ADHD treatment in animal models.

Jurica P, Struzik ZR, Li J, Horiuchi M, Hiroyama S, Takahara Y, Nishitomi K, Ogawa K, Cichocki A. Jurica P, et al. Among authors: hiroyama s. J Neurosci Methods. 2018 Mar 15;298:24-32. doi: 10.1016/j.jneumeth.2018.01.002. Epub 2018 Jan 31. J Neurosci Methods. 2018. PMID: 29366980 Free article.

8

Quantitative evaluation of hepatic integrin α_vβ₃ expression by positron emission tomography imaging using ¹⁸F-FPP-RGD₂ in rats with non-alcoholic steatohepatitis.

Hiroyama S, Rokugawa T, Ito M, Iimori H, Morita I, Maeda H, Fujisawa K, Matsunaga K, Shimosegawa E, Abe K. Hiroyama S, et al. EJNMMI Res. 2020 Oct 7;10(1):118. doi: 10.1186/s13550-020-00704-3. EJNMMI Res. 2020. PMID: 33026561 Free PMC article.

9

Rational Design of Novel 1,3-Oxazine Based β-Secretase (BACE1) Inhibitors: Incorporation of a Double Bond To Reduce P-gp Efflux Leading to Robust Aβ Reduction in the Brain.

Fuchino K, Mitsuoka Y, Masui M, Kurose N, Yoshida S, Komano K, Yamamoto T, Ogawa M, Unemura C, Hosono M, Ito H, Sakaguchi G, Ando S, Ohnishi S, Kido Y, Fukushima T, Miyajima H, Hiroyama S, Koyabu K, Dhuyvetter D, Borghys H, Gijsen HJM, Yamano Y, Iso Y, Kusakabe KI. Fuchino K, et al. Among authors: hiroyama s. J Med Chem. 2018 Jun 28;61(12):5122-5137. doi: 10.1021/acs.jmedchem.8b00002. Epub 2018 May 23. J Med Chem. 2018. PMID: 29733614

10

Effects of endogenous ligands on the biological role of human serum albumin in S-nitrosylation.

Ishima Y, Akaike T, Kragh-Hansen U, Hiroyama S, Sawa T, Maruyama T, Kai T, Otagiri M. Ishima Y, et al. Among authors: hiroyama s. Biochem Biophys Res Commun. 2007 Dec 28;364(4):790-5. doi: 10.1016/j.bbrc.2007.10.094. Epub 2007 Oct 26. Biochem Biophys Res Commun. 2007. PMID: 18273439

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