Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 250

1.

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces.

Jooss NJ, De Simone I, Provenzale I, Fernández DI, Brouns SLN, Farndale RW, Henskens YMC, Kuijpers MJE, Ten Cate H, van der Meijden PEJ, Cavill R, Heemskerk JWM.

Int J Mol Sci. 2019 Jun 7;20(11). pii: E2788. doi: 10.3390/ijms20112788.

2.

Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases.

Kiran Gotru S, van Geffen JP, Nagy M, Mammadova-Bach E, Eilenberger J, Volz J, Manukjan G, Schulze H, Wagner L, Eber S, Schambeck C, Deppermann C, Brouns S, Nurden P, Greinacher A, Sachs U, Nieswandt B, Hermanns HM, Heemskerk JWM, Braun A.

Sci Rep. 2019 Jun 6;9(1):8333. doi: 10.1038/s41598-019-44751-w.

3.

Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.

Gorman KM, Meyer E, Grozeva D, Spinelli E, McTague A, Sanchis-Juan A, Carss KJ, Bryant E, Reich A, Schneider AL, Pressler RM, Simpson MA, Debelle GD, Wassmer E, Morton J, Sieciechowicz D, Jan-Kamsteeg E, Paciorkowski AR, King MD, Cross JH, Poduri A, Mefford HC, Scheffer IE, Haack TB, McCullagh G; Deciphering Developmental Disorders Study; UK10K Consortium; NIHR BioResource, Millichap JJ, Carvill GL, Clayton-Smith J, Maher ER, Raymond FL, Kurian MA.

Am J Hum Genet. 2019 May 2;104(5):948-956. doi: 10.1016/j.ajhg.2019.03.005. Epub 2019 Apr 11.

PMID:
30982612
4.

Comparison of the GPVI inhibitors losartan and honokiol.

Onselaer MB, Nagy M, Pallini C, Pike JA, Perrella G, Quintanilla LG, Eble JA, Poulter NS, Heemskerk JWM, Watson SP.

Platelets. 2019 Mar 8:1-11. doi: 10.1080/09537104.2019.1585526. [Epub ahead of print]

PMID:
30849265
5.

High-throughput elucidation of thrombus formation reveals sources of platelet function variability.

van Geffen JP, Brouns SLN, Batista J, McKinney H, Kempster C, Nagy M, Sivapalaratnam S, Baaten CCFMJ, Bourry N, Frontini M, Jurk K, Krause M, Pillitteri D, Swieringa F, Verdoold R, Cavill R, Kuijpers MJE, Ouwehand WH, Downes K, Heemskerk JWM.

Haematologica. 2019 Jun;104(6):1256-1267. doi: 10.3324/haematol.2018.198853. Epub 2018 Dec 13.

6.

Store-operated calcium entry in thrombosis and thrombo-inflammation.

Mammadova-Bach E, Nagy M, Heemskerk JWM, Nieswandt B, Braun A.

Cell Calcium. 2019 Jan;77:39-48. doi: 10.1016/j.ceca.2018.11.005. Epub 2018 Nov 23. Review.

PMID:
30530092
7.

Tyrosine Kinase Inhibitor Pazopanib Inhibits Platelet Procoagulant Activity in Renal Cell Carcinoma Patients.

Tullemans BME, Nagy M, Sabrkhany S, Griffioen AW, Oude Egbrink MGA, Aarts M, Heemskerk JWM, Kuijpers MJE.

Front Cardiovasc Med. 2018 Oct 16;5:142. doi: 10.3389/fcvm.2018.00142. eCollection 2018.

8.

Platelet biology and functions: new concepts and clinical perspectives.

van der Meijden PEJ, Heemskerk JWM.

Nat Rev Cardiol. 2019 Mar;16(3):166-179. doi: 10.1038/s41569-018-0110-0. Review.

PMID:
30429532
9.

A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding.

Baaten CCFMJ, Meacham S, de Witt SM, Feijge MAH, Adams DJ, Akkerman JN, Cosemans JMEM, Grassi L, Jupe S, Kostadima M, Mattheij NJA, Prins MH, Ramirez-Solis R, Soehnlein O, Swieringa F, Weber C, White JK, Ouwehand WH, Heemskerk JWM.

Blood. 2018 Dec 13;132(24):e35-e46. doi: 10.1182/blood-2018-02-831982. Epub 2018 Oct 1. Review.

PMID:
30275110
10.

Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects.

Baaten CCFMJ, Swieringa F, Misztal T, Mastenbroek TG, Feijge MAH, Bock PE, Donners MMPC, Collins PW, Li R, van der Meijden PEJ, Heemskerk JWM.

Blood Adv. 2018 Sep 25;2(18):2320-2331. doi: 10.1182/bloodadvances.2017011544.

11.

Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data.

Farmery JHR, Smith ML; NIHR BioResource - Rare Diseases, Lynch AG.

Sci Rep. 2018 Sep 3;8(1):13376. doi: 10.1038/s41598-018-31524-0.

12.

Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?

Slater A, Perrella G, Onselaer MB, Martin EM, Gauer JS, Xu RG, Heemskerk JW, Ariëns RAS, Watson SP.

Platelets. 2019;30(3):281-289. doi: 10.1080/09537104.2018.1508649. Epub 2018 Aug 15.

PMID:
30110193
13.

Integrating platelet and coagulation activation in fibrin clot formation.

Swieringa F, Spronk HMH, Heemskerk JWM, van der Meijden PEJ.

Res Pract Thromb Haemost. 2018 May 20;2(3):450-460. doi: 10.1002/rth2.12107. eCollection 2018 Jul. Review.

14.

Acquired platelet antagonism: off-target antiplatelet effects of malignancy treatment with tyrosine kinase inhibitors.

Tullemans BME, Heemskerk JWM, Kuijpers MJE.

J Thromb Haemost. 2018 Sep;16(9):1686-1699. doi: 10.1111/jth.14225. Epub 2018 Aug 9. Review.

PMID:
29975003
15.

De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures.

Ito Y, Carss KJ, Duarte ST, Hartley T, Keren B, Kurian MA, Marey I, Charles P, Mendonça C, Nava C, Pfundt R, Sanchis-Juan A, van Bokhoven H, van Essen A, van Ravenswaaij-Arts C; NIHR BioResource; Care4Rare Canada Consortium, Boycott KM, Kernohan KD, Dyack S, Raymond FL.

Am J Hum Genet. 2018 Jul 5;103(1):144-153. doi: 10.1016/j.ajhg.2018.06.001. Epub 2018 Jun 28.

16.

Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes.

Whitworth J, Smith PS, Martin JE, West H, Luchetti A, Rodger F, Clark G, Carss K, Stephens J, Stirrups K, Penkett C, Mapeta R, Ashford S, Megy K, Shakeel H, Ahmed M, Adlard J, Barwell J, Brewer C, Casey RT, Armstrong R, Cole T, Evans DG, Fostira F, Greenhalgh L, Hanson H, Henderson A, Hoffman J, Izatt L, Kumar A, Kwong A, Lalloo F, Ong KR, Paterson J, Park SM, Chen-Shtoyerman R, Searle C, Side L, Skytte AB, Snape K, Woodward ER; NIHR BioResource Rare Diseases Consortium, Tischkowitz MD, Maher ER.

Am J Hum Genet. 2018 Jul 5;103(1):3-18. doi: 10.1016/j.ajhg.2018.04.013. Epub 2018 Jun 14.

17.

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice.

Hofmann I, Geer MJ, Vögtle T, Crispin A, Campagna DR, Barr A, Calicchio ML, Heising S, van Geffen JP, Kuijpers MJE, Heemskerk JWM, Eble JA, Schmitz-Abe K, Obeng EA, Douglas M, Freson K, Pondarré C, Favier R, Jarvis GE, Markianos K, Turro E, Ouwehand WH, Mazharian A, Fleming MD, Senis YA.

Blood. 2018 Sep 27;132(13):1399-1412. doi: 10.1182/blood-2017-08-802769. Epub 2018 Jun 13.

18.

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis.

Geer MJ, van Geffen JP, Gopalasingam P, Vögtle T, Smith CW, Heising S, Kuijpers MJE, Tullemans BME, Jarvis GE, Eble JA, Jeeves M, Overduin M, Heemskerk JWM, Mazharian A, Senis YA.

Blood. 2018 Sep 27;132(13):1413-1425. doi: 10.1182/blood-2017-10-802975. Epub 2018 Jun 11.

19.

Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy.

Baaten CCFMJ, Moenen FCJI, Henskens YMC, Swieringa F, Wetzels RJH, van Oerle R, Heijnen HFG, Ten Cate H, Holloway GP, Beckers EAM, Heemskerk JWM, van der Meijden PEJ.

Haematologica. 2018 Sep;103(9):1557-1567. doi: 10.3324/haematol.2017.185165. Epub 2018 Jun 7.

20.

Platelet proteomics: from discovery to diagnosis.

Looße C, Swieringa F, Heemskerk JWM, Sickmann A, Lorenz C.

Expert Rev Proteomics. 2018 Jun;15(6):467-476. doi: 10.1080/14789450.2018.1480111. Epub 2018 Jun 8. Review.

PMID:
29787335

Supplemental Content

Loading ...
Support Center