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Items: 1 to 20 of 334


Salivary α-amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study.

Valsesia A, Kulkarni SS, Marquis J, Leone P, Mironova P, Walter O, Hjorth MF, Descombes P, Hager J, Saris WH, Astrup A, Darimont C, O'Callaghan NJ.

Am J Clin Nutr. 2019 Apr 1;109(4):1029-1037. doi: 10.1093/ajcn/nqy363.


Analysis of 1508 plasma samples by capillary flow data-independent acquisition profiles proteomics of weight loss and maintenance.

Bruderer R, Muntel J, Müller S, Bernhardt OM, Gandhi T, Cominetti O, Macron C, Carayol J, Rinner O, Astrup A, Saris WHM, Hager J, Valsesia A, Dayon L, Reiter L.

Mol Cell Proteomics. 2019 Apr 4. pii: mcp.RA118.001288. doi: 10.1074/mcp.RA118.001288. [Epub ahead of print]


Werner Syndrome Helicase Is Required for the Survival of Cancer Cells with Microsatellite Instability.

Kategaya L, Perumal SK, Hager JH, Belmont LD.

iScience. 2019 Mar 29;13:488-497. doi: 10.1016/j.isci.2019.02.006. Epub 2019 Mar 18.


Cardiovascular prevention and at-risk behaviours in a large population of amateur rugby players.

Chagué F, Georges M, Gudjoncik A, Hermerel T, Garet G, Israël J, Hager JP, Aviat P, Laurent Y, Gremeaux V, Cottin Y, Zeller M.

Eur J Prev Cardiol. 2019 Mar 19:2047487319837066. doi: 10.1177/2047487319837066. [Epub ahead of print]


Genome-wide identification of circulating-miRNA expression quantitative trait loci reveals the role of several miRNAs in the regulation of Cardiometabolic phenotypes.

Nikpay M, Beehler K, Valsesia A, Hager J, Harper ME, Dent R, McPherson R.

Cardiovasc Res. 2019 Jan 31. doi: 10.1093/cvr/cvz030. [Epub ahead of print]


Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism.

Valsesia A, Wang QP, Gheldof N, Carayol J, Ruffieux H, Clark T, Shenton V, Oyston LJ, Lefebvre G, Metairon S, Chabert C, Walter O, Mironova P, Lau P, Descombes P, Viguerie N, Langin D, Harper ME, Astrup A, Saris WH, Dent R, Neely GG, Hager J.

Nat Commun. 2019 Feb 1;10(1):540. doi: 10.1038/s41467-019-08492-8.


Combined Anterior Cruciate and Anterolateral Ligament Reconstruction in the Professional Athlete: Clinical Outcomes From the Scientific Anterior Cruciate Ligament Network International Study Group in a Series of 70 Patients With a Minimum Follow-Up of 2 Years.

Rosenstiel N, Praz C, Ouanezar H, Saithna A, Fournier Y, Hager JP, Thaunat M, Sonnery-Cottet B.

Arthroscopy. 2019 Mar;35(3):885-892. doi: 10.1016/j.arthro.2018.09.020. Epub 2019 Jan 29.


Maximizing ER-α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927.

Kahraman M, Govek SP, Nagasawa JY, Lai A, Bonnefous C, Douglas K, Sensintaffar J, Liu N, Lee K, Aparicio A, Kaufman J, Qian J, Shao G, Prudente R, Joseph JD, Darimont B, Brigham D, Heyman R, Rix PJ, Hager JH, Smith ND.

ACS Med Chem Lett. 2018 Dec 6;10(1):50-55. doi: 10.1021/acsmedchemlett.8b00414. eCollection 2019 Jan 10.


Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.

Joseph JD, Darimont B, Zhou W, Arrazate A, Young A, Ingalla E, Walter K, Blake RA, Nonomiya J, Guan Z, Kategaya L, Govek SP, Lai AG, Kahraman M, Brigham D, Sensintaffar J, Lu N, Shao G, Qian J, Grillot K, Moon M, Prudente R, Bischoff E, Lee KJ, Bonnefous C, Douglas KL, Julien JD, Nagasawa JY, Aparicio A, Kaufman J, Haley B, Giltnane JM, Wertz IE, Lackner MR, Nannini MA, Sampath D, Schwarz L, Manning HC, Tantawy MN, Arteaga CL, Heyman RA, Rix PJ, Friedman L, Smith ND, Metcalfe C, Hager JH.

Elife. 2019 Jan 7;8. pii: e44851. doi: 10.7554/eLife.44851.


Selective estrogen receptor degraders with novel structural motifs induce regression in a tamoxifen-resistant breast cancer xenograft.

Govek SP, Bonnefous C, Julien JD, Nagasawa JY, Kahraman M, Lai AG, Douglas KL, Aparicio AM, Darimont BD, Grillot KL, Joseph JD, Kaufman JA, Lee KJ, Lu N, Moon MJ, Prudente RY, Sensintaffar J, Rix PJ, Hager JH, Smith ND.

Bioorg Med Chem Lett. 2019 Feb 1;29(3):367-372. doi: 10.1016/j.bmcl.2018.12.042. Epub 2018 Dec 19.


Obesity shows preserved plasma proteome in large independent clinical cohorts.

Cominetti O, Núñez Galindo A, Corthésy J, Valsesia A, Irincheeva I, Kussmann M, Saris WHM, Astrup A, McPherson R, Harper ME, Dent R, Hager J, Dayon L.

Sci Rep. 2018 Nov 19;8(1):16981. doi: 10.1038/s41598-018-35321-7.


The Quality of Tuberculosis Care in Urban Migrant Clinics in China.

Xue H, Hager J, An Q, Liu K, Zhang J, Auden E, Yang B, Yang J, Liu H, Nie J, Wang A, Zhou C, Shi Y, Sylvia S.

Int J Environ Res Public Health. 2018 Sep 18;15(9). pii: E2037. doi: 10.3390/ijerph15092037.


Impact of resection on overall survival of recurrent Glioblastoma in elderly patients.

Hager J, Herrmann E, Kammerer S, Dinc N, Won SY, Senft C, Seifert V, Marquardt G, Quick-Weller J.

Clin Neurol Neurosurg. 2018 Nov;174:21-25. doi: 10.1016/j.clineuro.2018.08.033. Epub 2018 Sep 1.


Identification of an Orally Bioavailable Chromene-Based Selective Estrogen Receptor Degrader (SERD) That Demonstrates Robust Activity in a Model of Tamoxifen-Resistant Breast Cancer.

Nagasawa J, Govek S, Kahraman M, Lai A, Bonnefous C, Douglas K, Sensintaffar J, Lu N, Lee K, Aparicio A, Kaufman J, Qian J, Shao G, Prudente R, Joseph JD, Darimont B, Brigham D, Maheu K, Heyman R, Rix PJ, Hager JH, Smith ND.

J Med Chem. 2018 Sep 13;61(17):7917-7928. doi: 10.1021/acs.jmedchem.8b00921. Epub 2018 Sep 4.


Plasma metabolites and lipids predict insulin sensitivity improvement in obese, nondiabetic individuals after a 2-phase dietary intervention.

Meyer A, Montastier E, Hager J, Saris WHM, Astrup A, Viguerie N, Valsesia A.

Am J Clin Nutr. 2018 Jul 1;108(1):13-23. doi: 10.1093/ajcn/nqy087.


Fast and Accurate Approaches for Large-Scale, Automated Mapping of Food Diaries on Food Composition Tables.

Lamarine M, Hager J, Saris WHM, Astrup A, Valsesia A.

Front Nutr. 2018 May 9;5:38. doi: 10.3389/fnut.2018.00038. eCollection 2018.


Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study.

Hess AL, Carayol J, Blædel T, Hager J, Di Cara A, Astrup A, Saris WHM, Larsen LH, Valsesia A.

Genes Nutr. 2018 Apr 2;13:7. doi: 10.1186/s12263-018-0597-3. eCollection 2018.


CD117- and vimentin-positive telocytes in the bovine teat sphincter.

Wagener MG, Leonhard-Marek S, Häger JD, Pfarrer C.

Anat Histol Embryol. 2018 Jun;47(3):268-270. doi: 10.1111/ahe.12347. Epub 2018 Mar 5.


Workload, Fatigue, and Muscle Damage in an Under-20 Rugby Union Team Over an Intensified International Tournament.

Lacome M, Carling C, Hager JP, Dine G, Piscione J.

Int J Sports Physiol Perform. 2018 Sep 1;13(8):1059-1066. doi: 10.1123/ijspp.2017-0464. Epub 2018 Sep 9.


Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator.

Carayol J, Chabert C, Di Cara A, Armenise C, Lefebvre G, Langin D, Viguerie N, Metairon S, Saris WHM, Astrup A, Descombes P, Valsesia A, Hager J.

Nat Commun. 2017 Dec 12;8(1):2084. doi: 10.1038/s41467-017-02182-z.

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