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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 3
1991 14
1992 19
1993 14
1994 15
1995 8
1996 20
1997 23
1998 9
1999 16
2000 15
2001 16
2002 17
2003 10
2004 8
2005 6
2006 6
2007 7
2008 5
2009 7
2010 4
2011 9
2012 14
2013 13
2014 7
2015 9
2016 13
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2023 13
2024 5

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357 results

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Page 1
Association of HLA-DR2-Related Haplotype (HLA-DRB5*01-DRB1*1501-DQB1*0602) in Patients with Multiple Sclerosis in Khuzestan Province.
Delfan N, Galehdari H, Ghanbari Mardasi F, Zabihi R, Latifi Pakdehi T, Seifi T, Majdinasab N. Delfan N, et al. Iran J Child Neurol. 2021 Summer;15(3):35-46. doi: 10.22037/ijcn.v14i4.18795. Iran J Child Neurol. 2021. PMID: 34282361 Free PMC article.
RESULTS: HLA-DRB5*01 (-) -DQB1*0602 (-) as the most common HLA haplotype was found in both patient and control groups. ...CONCLUSION: There was no association between HLA-DR2 and MS susceptibility. However, the higher HLA-DRB5*01 (+) -DRB …
RESULTS: HLA-DRB5*01 (-) -DQB1*0602 (-) as the most common HLA haplotype was found in both patient and control groups. …
The novel HLA-DRB5*02:35 allele characterized by two different sequencing-based typing techniques.
Dhuyser A, Pérès M, Morel T, Clément S, Aarnink A. Dhuyser A, et al. HLA. 2023 Jul;102(1):116-117. doi: 10.1111/tan.15017. Epub 2023 Mar 13. HLA. 2023. PMID: 36908265
The novel allele HLA-DRB5*02:35 differs from HLA-DRB5*02:02:01 by one non-synonymous nucleotide substitution in exon 2....
The novel allele HLA-DRB5*02:35 differs from HLA-DRB5*02:02:01 by one non-synonymous nucleotide substitution in …
The Shared Mechanism and Candidate Drugs of Multiple Sclerosis and Sjögren's Syndrome Analyzed by Bioinformatics Based on GWAS and Transcriptome Data.
Hong X, Wang X, Rang X, Yin X, Zhang X, Wang R, Wang D, Zhao T, Fu J. Hong X, et al. Front Immunol. 2022 Mar 9;13:857014. doi: 10.3389/fimmu.2022.857014. eCollection 2022. Front Immunol. 2022. PMID: 35356004 Free PMC article.
RESULTS: Based on GWAS data, we found 14 hub common susceptibility genes (HLA-DRB1, HLA-DRA, STAT3, JAK1, HLA-B, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRB5, HLA-DPA1, HLA-DPB1, TYK2, IL2RA, and MAPK1), with 8 drugs …
RESULTS: Based on GWAS data, we found 14 hub common susceptibility genes (HLA-DRB1, HLA-DRA, STAT3, JAK1, HLA-B, HLA …
HLA-DRA/HLA-DRB5 polymorphism affects risk of sporadic ALS and survival in a southwest Chinese cohort.
Yang X, Zheng J, Tian S, Chen Y, An R, Zhao Q, Xu Y. Yang X, et al. J Neurol Sci. 2017 Feb 15;373:124-128. doi: 10.1016/j.jns.2016.12.055. Epub 2016 Dec 28. J Neurol Sci. 2017. PMID: 28131168
A recent genome-wide association study has linked risk of FTD with polymorphisms in the HLA-DRA/HLA-DRB5 gene (rs9268877, rs9268856), BTNL2 gene (rs1980493), and RAB38/CTSC gene (rs302668). ...
A recent genome-wide association study has linked risk of FTD with polymorphisms in the HLA-DRA/HLA-DRB5 gene (rs926887 …
Association of HLA-DRB1*15:02 and DRB5*01:02 allele with the susceptibility to systemic sclerosis in Thai patients.
Louthrenoo W, Kasitanon N, Wichainun R, Wangkaew S, Sukitawut W, Ohnogi Y, Nakaue N, Kuwata S, Takeuchi F. Louthrenoo W, et al. Rheumatol Int. 2013 Aug;33(8):2069-77. doi: 10.1007/s00296-013-2686-3. Epub 2013 Feb 13. Rheumatol Int. 2013. PMID: 23404077
The AF of the HLA-DRB5*01:02 allele was also increased in all SSc patients (27.0 vs 12.6%, Pc = 0.0166) and in SSc patients with anti-Scl70+ (29.4%, Pc = 0.0124). ...In addition, there was no significant association between clinical manifestations among individuals …
The AF of the HLA-DRB5*01:02 allele was also increased in all SSc patients (27.0 vs 12.6%, Pc = 0.0166) and in SSc patients wi …
HLA-DRB5 promotes immune thrombocytopenia via activating CD8(+) T cells.
Ye Q, Ying Q, Chen Y, Liao C, Li A. Ye Q, et al. Open Med (Wars). 2024 May 23;19(1):20240955. doi: 10.1515/med-2024-0955. eCollection 2024. Open Med (Wars). 2024. PMID: 38799252 Free PMC article.
Based on the critical role of human leukocyte antigen class II heterodimer beta5 (HLA-DRB5) in immune system, we herein investigated its effect on ITP. ...HLA-DRB5 knockdown mitigated ITP by increasing peripheral PLT level, downregulating expressions o …
Based on the critical role of human leukocyte antigen class II heterodimer beta5 (HLA-DRB5) in immune system, we herein invest …
Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis.
Caillier SJ, Briggs F, Cree BA, Baranzini SE, Fernandez-Viña M, Ramsay PP, Khan O, Royal W 3rd, Hauser SL, Barcellos LF, Oksenberg JR. Caillier SJ, et al. J Immunol. 2008 Oct 15;181(8):5473-80. doi: 10.4049/jimmunol.181.8.5473. J Immunol. 2008. PMID: 18832704 Free PMC article.
Although significant associations with both HLA-DRB1 and HLA-DRB5 loci were present, HLA-DRB1*1503 was associated with MS in the absence of HLA-DRB5, providing evidence for HLA-DRB1 as the primary susceptibility gene. ...Thus, H …
Although significant associations with both HLA-DRB1 and HLA-DRB5 loci were present, HLA-DRB1*1503 was associate …
Epigenome-wide methylation haplotype association analysis identified HLA-DRB1, HLA-DRB5 and HLA-DQB1 as risk factors for rheumatoid arthritis.
Xu J, Chen H, Sun C, Wei S, Tao J, Jia Z, Chen X, Lv W, Lv H, Tang G, Jiang Y, Zhang M. Xu J, et al. Int J Immunogenet. 2023 Dec;50(6):291-298. doi: 10.1111/iji.12637. Epub 2023 Sep 9. Int J Immunogenet. 2023. PMID: 37688529
Subsequently, combined with gene optimization, eight RA-risk meplotypes were identified on three risk genes: HLA-DRB1, HLA-DRB5 and HLA-DQB1. Our results reported the relationship between DNA methylation pattern on HLA-DQB1 and the risk of RA fo …
Subsequently, combined with gene optimization, eight RA-risk meplotypes were identified on three risk genes: HLA-DRB1, HLA- …
HLA-DRB5 genotyping by PCR-RFLP.
Trejaut J, Dunckley H. Trejaut J, et al. Tissue Antigens. 1994 Jan;43(1):60-3. doi: 10.1111/j.1399-0039.1994.tb02300.x. Tissue Antigens. 1994. PMID: 7912860 No abstract available.
Copy number variations of HLA-DRB5 is associated with systemic lupus erythematosus risk in Chinese Han population.
Wu L, Guo S, Yang D, Ma Y, Ji H, Chen Y, Zhang J, Wang Y, Jin L, Wang J, Liu J. Wu L, et al. Acta Biochim Biophys Sin (Shanghai). 2014 Feb;46(2):155-60. doi: 10.1093/abbs/gmt137. Epub 2013 Dec 22. Acta Biochim Biophys Sin (Shanghai). 2014. PMID: 24366815 Free article.
Then, in the validation stage, 135 SLE patients and 219 matched healthy subjects were investigated for the CNVS of gene HLA-DRB5 by AccuCopy technology. Quantitative polymerase chain reaction was carried out to determine the copy number (CN) and mRNA level of …
Then, in the validation stage, 135 SLE patients and 219 matched healthy subjects were investigated for the CNVS of gene HLA-DRB5 …
357 results