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Items: 1 to 20 of 116

1.

Structure and Catalytic Mechanism of a Bacterial Friedel-Crafts Acylase.

Pavkov-Keller T, Schmidt NG, Żądło-Dobrowolska A, Kroutil W, Gruber K.

Chembiochem. 2018 Oct 14. doi: 10.1002/cbic.201800462. [Epub ahead of print]

PMID:
30318713
2.

Oxidative cyclization of N-methyl-dopa by a fungal flavoenzyme of the amine oxidase family.

Lahham M, Pavkov-Keller T, Fuchs M, Niederhauser J, Chalhoub G, Daniel B, Kroutil W, Gruber K, Macheroux P.

J Biol Chem. 2018 Nov 2;293(44):17021-17032. doi: 10.1074/jbc.RA118.004227. Epub 2018 Sep 7.

3.

Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases.

Heckenbichler K, Schweiger A, Brandner LA, Binter A, Toplak M, Macheroux P, Gruber K, Breinbauer R.

Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7240-7244. doi: 10.1002/anie.201802962. Epub 2018 May 14.

4.

Identification of Key Residues for Enzymatic Carboxylate Reduction.

Stolterfoht H, Steinkellner G, Schwendenwein D, Pavkov-Keller T, Gruber K, Winkler M.

Front Microbiol. 2018 Feb 19;9:250. doi: 10.3389/fmicb.2018.00250. eCollection 2018.

5.

A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain.

Hromić-Jahjefendić A, Jajčanin Jozić N, Kazazić S, Grabar Branilović M, Karačić Z, Schrittwieser JH, Das KMP, Tomin M, Oberer M, Gruber K, Abramić M, Tomić S.

PLoS One. 2017 Nov 30;12(11):e0188915. doi: 10.1371/journal.pone.0188915. eCollection 2017.

6.

Crystal structure of dipeptidyl peptidase III from the human gut symbiont Bacteroides thetaiotaomicron.

Sabljić I, Meštrović N, Vukelić B, Macheroux P, Gruber K, Luić M, Abramić M.

PLoS One. 2017 Nov 2;12(11):e0187295. doi: 10.1371/journal.pone.0187295. eCollection 2017.

7.

Regioselective para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase.

Payer SE, Marshall SA, Bärland N, Sheng X, Reiter T, Dordic A, Steinkellner G, Wuensch C, Kaltwasser S, Fisher K, Rigby SEJ, Macheroux P, Vonck J, Gruber K, Faber K, Himo F, Leys D, Pavkov-Keller T, Glueck SM.

Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13893-13897. doi: 10.1002/anie.201708091. Epub 2017 Oct 2.

8.

Small cause, large effect: Structural characterization of cutinases from Thermobifida cellulosilytica.

Ribitsch D, Hromic A, Zitzenbacher S, Zartl B, Gamerith C, Pellis A, Jungbauer A, Łyskowski A, Steinkellner G, Gruber K, Tscheliessnig R, Herrero Acero E, Guebitz GM.

Biotechnol Bioeng. 2017 Nov;114(11):2481-2488. doi: 10.1002/bit.26372. Epub 2017 Aug 15.

PMID:
28671263
9.

Biocatalytic Friedel-Crafts Acylation and Fries Reaction.

Schmidt NG, Pavkov-Keller T, Richter N, Wiltschi B, Gruber K, Kroutil W.

Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7615-7619. doi: 10.1002/anie.201703270. Epub 2017 May 23.

10.

Structure, biochemical and kinetic properties of recombinant Pst2p from Saccharomyces cerevisiae, a FMN-dependent NAD(P)H:quinone oxidoreductase.

Koch K, Hromic A, Sorokina M, Strandback E, Reisinger M, Gruber K, Macheroux P.

Biochim Biophys Acta Proteins Proteom. 2017 Aug;1865(8):1046-1056. doi: 10.1016/j.bbapap.2017.05.005. Epub 2017 May 10.

11.

Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily.

Lanfranchi E, Pavkov-Keller T, Koehler EM, Diepold M, Steiner K, Darnhofer B, Hartler J, Van Den Bergh T, Joosten HJ, Gruber-Khadjawi M, Thallinger GG, Birner-Gruenberger R, Gruber K, Winkler M, Glieder A.

Sci Rep. 2017 May 3;7:46738. doi: 10.1038/srep46738. Erratum in: Sci Rep. 2017 May 26;7:46834.

12.

A conserved inter-domain communication mechanism regulates the ATPase activity of the AAA-protein Drg1.

Prattes M, Loibl M, Zisser G, Luschnig D, Kappel L, Rössler I, Grassegger M, Hromic A, Krieger E, Gruber K, Pertschy B, Bergler H.

Sci Rep. 2017 Mar 17;7:44751. doi: 10.1038/srep44751.

13.

Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1).

Lienhart WD, Strandback E, Gudipati V, Koch K, Binter A, Uhl MK, Rantasa DM, Bourgeois B, Madl T, Zangger K, Gruber K, Macheroux P.

FEBS J. 2017 Apr;284(8):1233-1245. doi: 10.1111/febs.14051. Epub 2017 Mar 17.

14.

Crystal Structure and Catalytic Mechanism of CouO, a Versatile C-Methyltransferase from Streptomyces rishiriensis.

Pavkov-Keller T, Steiner K, Faber M, Tengg M, Schwab H, Gruber-Khadjawi M, Gruber K.

PLoS One. 2017 Feb 2;12(2):e0171056. doi: 10.1371/journal.pone.0171056. eCollection 2017.

15.

Discovery and structural characterisation of new fold type IV-transaminases exemplify the diversity of this enzyme fold.

Pavkov-Keller T, Strohmeier GA, Diepold M, Peeters W, Smeets N, Schürmann M, Gruber K, Schwab H, Steiner K.

Sci Rep. 2016 Dec 1;6:38183. doi: 10.1038/srep38183.

16.

Chlorophyll-Derived Yellow Phyllobilins of Higher Plants as Medium-Responsive Chiral Photoswitches.

Li C, Wurst K, Jockusch S, Gruber K, Podewitz M, Liedl KR, Kräutler B.

Angew Chem Int Ed Engl. 2016 Dec 19;55(51):15760-15765. doi: 10.1002/anie.201609481. Epub 2016 Nov 28.

17.

PpEst is a novel PBAT degrading polyesterase identified by proteomic screening of Pseudomonas pseudoalcaligenes.

Wallace PW, Haernvall K, Ribitsch D, Zitzenbacher S, Schittmayer M, Steinkellner G, Gruber K, Guebitz GM, Birner-Gruenberger R.

Appl Microbiol Biotechnol. 2017 Mar;101(6):2291-2303. doi: 10.1007/s00253-016-7992-8. Epub 2016 Nov 21.

18.

Polyester hydrolysis is enhanced by a truncated esterase: Less is more.

Biundo A, Ribitsch D, Steinkellner G, Gruber K, Guebitz GM.

Biotechnol J. 2017 Aug;12(8). doi: 10.1002/biot.201600450. Epub 2016 Oct 11.

PMID:
27687520
19.

Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant.

Augustin P, Hromic A, Pavkov-Keller T, Gruber K, Macheroux P.

FEBS J. 2016 Oct;283(19):3587-3603. doi: 10.1111/febs.13828.

20.

Total Synthesis, Structure, and Biological Activity of Adenosylrhodibalamin, the Non-Natural Rhodium Homologue of Coenzyme B12.

Widner FJ, Lawrence AD, Deery E, Heldt D, Frank S, Gruber K, Wurst K, Warren MJ, Kräutler B.

Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11281-6. doi: 10.1002/anie.201603738. Epub 2016 Jun 29.

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