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Items: 6


Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis.

Borek WE, Groocock LM, Samejima I, Zou J, de Lima Alves F, Rappsilber J, Sawin KE.

Nat Commun. 2015 Aug 5;6:7929. doi: 10.1038/ncomms8929.


RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response.

Groocock LM, Nie M, Prudden J, Moiani D, Wang T, Cheltsov A, Rambo RP, Arvai AS, Hitomi C, Tainer JA, Luger K, Perry JJ, Lazzerini-Denchi E, Boddy MN.

EMBO Rep. 2014 May;15(5):601-8. doi: 10.1002/embr.201338369. Epub 2014 Apr 8.


Activation of the γ-tubulin complex by the Mto1/2 complex.

Lynch EM, Groocock LM, Borek WE, Sawin KE.

Curr Biol. 2014 Apr 14;24(8):896-903. doi: 10.1016/j.cub.2014.03.006. Epub 2014 Apr 3.


The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast.

Groocock LM, Prudden J, Perry JJ, Boddy MN.

Mol Cell Biol. 2012 Jan;32(2):276-87. doi: 10.1128/MCB.06184-11. Epub 2011 Nov 7.


Two distinct regions of Mto1 are required for normal microtubule nucleation and efficient association with the gamma-tubulin complex in vivo.

Samejima I, Miller VJ, Groocock LM, Sawin KE.

J Cell Sci. 2008 Dec 1;121(Pt 23):3971-80. doi: 10.1242/jcs.038414. Epub 2008 Nov 11.


Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.

Williams RS, Moncalian G, Williams JS, Yamada Y, Limbo O, Shin DS, Groocock LM, Cahill D, Hitomi C, Guenther G, Moiani D, Carney JP, Russell P, Tainer JA.

Cell. 2008 Oct 3;135(1):97-109. doi: 10.1016/j.cell.2008.08.017.

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