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A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids.

Narzt MS, Nagelreiter IM, Oskolkova O, Bochkov VN, Latreille J, Fedorova M, Ni Z, Sialana FJ, Lubec G, Filzwieser M, Laggner M, Bilban M, Mildner M, Tschachler E, Grillari J, Gruber F.

Redox Biol. 2019 Jan;20:467-482. doi: 10.1016/j.redox.2018.11.006. Epub 2018 Nov 13.


Inhibition of profibrotic microRNA-21 affects platelets and their releasate.

Barwari T, Eminaga S, Mayr U, Lu R, Armstrong PC, Chan MV, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley SR, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah AM, Ghevaert C, Warner TD, Fernández-Hernando C, Suárez Y, Mayr M.

JCI Insight. 2018 Nov 2;3(21). pii: 123335. doi: 10.1172/jci.insight.123335. [Epub ahead of print]


The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition.

Hager S, Korbula K, Bielec B, Grusch M, Pirker C, Schosserer M, Liendl L, Lang M, Grillari J, Nowikovsky K, Pape VFS, Mohr T, Szakács G, Keppler BK, Berger W, Kowol CR, Heffeter P.

Cell Death Dis. 2018 Oct 15;9(11):1052. doi: 10.1038/s41419-018-1102-z.


Establishment of keratinocyte cell lines from human hair follicles.

Wagner T, Gschwandtner M, Strajeriu A, Elbe-Bürger A, Grillari J, Grillari-Voglauer R, Greiner G, Golabi B, Tschachler E, Mildner M.

Sci Rep. 2018 Sep 7;8(1):13434. doi: 10.1038/s41598-018-31829-0.


Stabilization of the CD81 Large Extracellular Loop with De Novo Disulfide Bonds Improves Its Amenability for Peptide Grafting.

Vogt S, Stadlmayr G, Stadlbauer K, Sádio F, Andorfer P, Grillari J, Rüker F, Wozniak-Knopp G.

Pharmaceutics. 2018 Aug 27;10(3). pii: E138. doi: 10.3390/pharmaceutics10030138.


Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.

Cardoso AL, Fernandes A, Aguilar-Pimentel JA, de Angelis MH, Guedes JR, Brito MA, Ortolano S, Pani G, Athanasopoulou S, Gonos ES, Schosserer M, Grillari J, Peterson P, Tuna BG, Dogan S, Meyer A, van Os R, Trendelenburg AU.

Ageing Res Rev. 2018 Nov;47:214-277. doi: 10.1016/j.arr.2018.07.004. Epub 2018 Jul 30. Review.


Cellular Senescence and Inflammaging in Age-Related Diseases.

Olivieri F, Prattichizzo F, Grillari J, Balistreri CR.

Mediators Inflamm. 2018 Apr 17;2018:9076485. doi: 10.1155/2018/9076485. eCollection 2018. No abstract available.


Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype.

Terlecki-Zaniewicz L, Lämmermann I, Latreille J, Bobbili MR, Pils V, Schosserer M, Weinmüllner R, Dellago H, Skalicky S, Pum D, Almaraz JCH, Scheideler M, Morizot F, Hackl M, Gruber F, Grillari J.

Aging (Albany NY). 2018 May 19;10(5):1103-1132. doi: 10.18632/aging.101452.


Blocking negative effects of senescence in human skin fibroblasts with a plant extract.

Lämmermann I, Terlecki-Zaniewicz L, Weinmüllner R, Schosserer M, Dellago H, de Matos Branco AD, Autheried D, Sevcnikar B, Kleissl L, Berlin I, Morizot F, Lejeune F, Fuzzati N, Forestier S, Toribio A, Tromeur A, Weinberg L, Higareda Almaraz JC, Scheideler M, Rietveld M, El Ghalbzouri A, Tschachler E, Gruber F, Grillari J.

NPJ Aging Mech Dis. 2018 Apr 11;4:4. doi: 10.1038/s41514-018-0023-5. eCollection 2018.


Bone-related Circulating MicroRNAs miR-29b-3p, miR-550a-3p, and miR-324-3p and their Association to Bone Microstructure and Histomorphometry.

Feichtinger X, Muschitz C, Heimel P, Baierl A, Fahrleitner-Pammer A, Redl H, Resch H, Geiger E, Skalicky S, Dormann R, Plachel F, Pietschmann P, Grillari J, Hackl M, Kocijan R.

Sci Rep. 2018 Mar 20;8(1):4867. doi: 10.1038/s41598-018-22844-2.


Altered MicroRNA Profile in Osteoporosis Caused by Impaired WNT Signaling.

Mäkitie RE, Hackl M, Niinimäki R, Kakko S, Grillari J, Mäkitie O.

J Clin Endocrinol Metab. 2018 May 1;103(5):1985-1996. doi: 10.1210/jc.2017-02585.


Combinatorial in Vitro and in Silico Approach To Describe Shear-Force Dependent Uptake of Nanoparticles in Microfluidic Vascular Models.

Charwat V, Olmos Calvo I, Rothbauer M, Kratz SRA, Jungreuthmayer C, Zanghellini J, Grillari J, Ertl P.

Anal Chem. 2018 Mar 20;90(6):3651-3655. doi: 10.1021/acs.analchem.7b04788. Epub 2018 Feb 28.


OPP Labeling Enables Total Protein Synthesis Quantification in CHO Production Cell Lines at the Single-Cell Level.

Nagelreiter F, Coats MT, Klanert G, Gludovacz E, Borth N, Grillari J, Schosserer M.

Biotechnol J. 2018 Apr;13(4):e1700492. doi: 10.1002/biot.201700492. Epub 2018 Feb 15.


Cost-utility analysis of fracture risk assessment using microRNAs compared with standard tools and no monitoring in the Austrian female population.

Walter E, Dellago H, Grillari J, Dimai HP, Hackl M.

Bone. 2018 Mar;108:44-54. doi: 10.1016/j.bone.2017.12.017. Epub 2017 Dec 18.


Editorial: Non-coding RNA in aging and age-associated diseases - from intracellular regulators to hormone like actions.

Hackl M, Suh Y, Grillari J.

Mech Ageing Dev. 2017 Dec;168:1-2. doi: 10.1016/j.mad.2017.11.014. No abstract available.


The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy.

Schosserer M, Grillari J, Breitenbach M.

Front Oncol. 2017 Nov 23;7:278. doi: 10.3389/fonc.2017.00278. eCollection 2017. Review.


MicroRNAs and toxicology: A love marriage.

Schraml E, Hackl M, Grillari J.

Toxicol Rep. 2017 Nov 13;4:634-636. doi: 10.1016/j.toxrep.2017.11.001. eCollection 2017. Review.


Age-Induced Changes in White, Brite, and Brown Adipose Depots: A Mini-Review.

Schosserer M, Grillari J, Wolfrum C, Scheideler M.

Gerontology. 2018;64(3):229-236. doi: 10.1159/000485183. Epub 2017 Dec 7. Review.


Erratum: Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span.

Garschall K, Dellago H, Gáliková M, Schosserer M, Flatt T, Grillari J.

NPJ Aging Mech Dis. 2017 Aug 15;3:10. doi: 10.1038/s41514-017-0008-9. eCollection 2017.


OLR1 scavenger receptor knockdown affects mitotic gene expression but is dispensable for oxidized phospholipid- mediated stress signaling in SZ 95 sebocytes.

Nagelreiter IM, Parvardeh M, Narzt MS, Beer L, Kremslehner C, Muresan XM, Grillari J, Zouboulis CC, Tschachler E, Gruber F.

Mech Ageing Dev. 2018 Jun;172:35-44. doi: 10.1016/j.mad.2017.11.002. Epub 2017 Nov 21.


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