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Biological Activity of Flavonoids and Rare Sesquiterpene Lactones Isolated From Centaurea ragusina L.

Grienke U, Radić Brkanac S, Vujčić V, Urban E, Ivanković S, Stojković R, Rollinger JM, Kralj J, Brozovic A, Radić Stojković M.

Front Pharmacol. 2018 Aug 22;9:972. doi: 10.3389/fphar.2018.00972. eCollection 2018.


Lanostane Triterpenes from Gloeophyllum odoratum and Their Anti-Influenza Effects.

Grienke U, Zwirchmayr J, Peintner U, Urban E, Zehl M, Schmidtke M, Rollinger JM.

Planta Med. 2018 Aug 21. doi: 10.1055/a-0690-9236. [Epub ahead of print]


In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1.

Kirchweger B, Kratz JM, Ladurner A, Grienke U, Langer T, Dirsch VM, Rollinger JM.

Front Chem. 2018 Jul 2;6:242. doi: 10.3389/fchem.2018.00242. eCollection 2018.


Discovery of Bioactive Natural Products for the Treatment of Acute Respiratory Infections - An Integrated Approach.

Grienke U, Mair CE, Kirchmair J, Schmidtke M, Rollinger JM.

Planta Med. 2018 Jul;84(9-10):684-695. doi: 10.1055/a-0590-5153. Epub 2018 Mar 19.


Anti-Influenza Triterpene Saponins from the Bark of Burkea africana.

Mair CE, Grienke U, Wilhelm A, Urban E, Zehl M, Schmidtke M, Rollinger JM.

J Nat Prod. 2018 Mar 23;81(3):515-523. doi: 10.1021/acs.jnatprod.7b00774. Epub 2018 Feb 2.


Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5.

Ladurner A, Zehl M, Grienke U, Hofstadler C, Faur N, Pereira FC, Berry D, Dirsch VM, Rollinger JM.

Front Pharmacol. 2017 Jul 17;8:468. doi: 10.3389/fphar.2017.00468. eCollection 2017.


Natural products modulating the hERG channel: heartaches and hope.

Kratz JM, Grienke U, Scheel O, Mann SA, Rollinger JM.

Nat Prod Rep. 2017 Aug 2;34(8):957-980. doi: 10.1039/c7np00014f. Review.


Fast and Green - CO2 Based Extraction, Isolation, and Quantification of Phenolic Styrax Constituents.

Scheuba J, Wronski VK, Rollinger JM, Grienke U.

Planta Med. 2017 Aug;83(12-13):1068-1075. doi: 10.1055/s-0043-105499. Epub 2017 Mar 16.


Discovery and Characterization of Diazenylaryl Sulfonic Acids as Inhibitors of Viral and Bacterial Neuraminidases.

Hoffmann A, Richter M, von Grafenstein S, Walther E, Xu Z, Schumann L, Grienke U, Mair CE, Kramer C, Rollinger JM, Liedl KR, Schmidtke M, Kirchmair J.

Front Microbiol. 2017 Feb 15;8:205. doi: 10.3389/fmicb.2017.00205. eCollection 2017.


Pharmacokinetics of hERG Channel Blocking Voacangine in Wistar Rats Applying a Validated LC-ESI-MS/MS Method.

Mair CE, de Miranda Silva C, Grienke U, Kratz JM, Carreño F, Zimmermann ES, de Araújo BV, Dalla Costa T, Rollinger JM.

Planta Med. 2016 Jul;82(11-12):1030-8. doi: 10.1055/s-0042-107800. Epub 2016 Jun 3.


Discovery of prenylated flavonoids with dual activity against influenza virus and Streptococcus pneumoniae.

Grienke U, Richter M, Walther E, Hoffmann A, Kirchmair J, Makarov V, Nietzsche S, Schmidtke M, Rollinger JM.

Sci Rep. 2016 Jun 3;6:27156. doi: 10.1038/srep27156.


Dual Acting Neuraminidase Inhibitors Open New Opportunities to Disrupt the Lethal Synergism between Streptococcus pneumoniae and Influenza Virus.

Walther E, Xu Z, Richter M, Kirchmair J, Grienke U, Rollinger JM, Krumbholz A, Saluz HP, Pfister W, Sauerbrei A, Schmidtke M.

Front Microbiol. 2016 Mar 21;7:357. doi: 10.3389/fmicb.2016.00357. eCollection 2016.


Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements.

Grienke U, Mair CE, Saxena P, Baburin I, Scheel O, Ganzera M, Schuster D, Hering S, Rollinger JM.

J Agric Food Chem. 2015 Jun 17;63(23):5634-9. doi: 10.1021/acs.jafc.5b01901. Epub 2015 Jun 9.


Seasonal and geographical variations in the biochemical composition of the blue mussel (Mytilus edulis L.) from Ireland.

Fernández A, Grienke U, Soler-Vila A, Guihéneuf F, Stengel DB, Tasdemir D.

Food Chem. 2015 Jun 15;177:43-52. doi: 10.1016/j.foodchem.2014.12.062. Epub 2014 Dec 24.


Fungal strain matters: colony growth and bioactivity of the European medicinal polypores Fomes fomentarius, Fomitopsis pinicola and Piptoporus betulinus.

Dresch P, D Aguanno MN, Rosam K, Grienke U, Rollinger JM, Peintner U.

AMB Express. 2015 Jan 24;5(1):4. eCollection 2015 Dec.


Antipneumococcal activity of neuraminidase inhibiting artocarpin.

Walther E, Richter M, Xu Z, Kramer C, von Grafenstein S, Kirchmair J, Grienke U, Rollinger JM, Liedl KR, Slevogt H, Sauerbrei A, Saluz HP, Pfister W, Schmidtke M.

Int J Med Microbiol. 2015 May;305(3):289-97. doi: 10.1016/j.ijmm.2014.12.004. Epub 2014 Dec 18.


Accessing biological actions of Ganoderma secondary metabolites by in silico profiling.

Grienke U, Kaserer T, Pfluger F, Mair CE, Langer T, Schuster D, Rollinger JM.

Phytochemistry. 2015 Jun;114:114-24. doi: 10.1016/j.phytochem.2014.10.010. Epub 2014 Nov 6. Review.


European medicinal polypores--a modern view on traditional uses.

Grienke U, Zöll M, Peintner U, Rollinger JM.

J Ethnopharmacol. 2014 Jul 3;154(3):564-83. doi: 10.1016/j.jep.2014.04.030. Epub 2014 Apr 28. Review.


Computer-guided approach to access the anti-influenza activity of licorice constituents.

Grienke U, Braun H, Seidel N, Kirchmair J, Richter M, Krumbholz A, von Grafenstein S, Liedl KR, Schmidtke M, Rollinger JM.

J Nat Prod. 2014 Mar 28;77(3):563-70. doi: 10.1021/np400817j. Epub 2013 Dec 6.


Bioactive compounds from marine mussels and their effects on human health.

Grienke U, Silke J, Tasdemir D.

Food Chem. 2014 Jan 1;142:48-60. doi: 10.1016/j.foodchem.2013.07.027. Epub 2013 Jul 11. Review.


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