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11β-HSD1 inhibition reduces atherosclerosis in mice by altering proinflammatory gene expression in the vasculature.
Physiol Genomics. 2013 Jan 7;45(1):47-57. doi: 10.1152/physiolgenomics.00109.2012. Epub 2012 Nov 20.
Physiol Genomics. 2013.
PMID: 23170035
11 Beta-hydroxysteroid dehydrogenase type 1 is induced in human monocytes upon differentiation to macrophages.
Thieringer R, Le Grand CB, Carbin L, Cai TQ, Wong B, Wright SD, Hermanowski-Vosatka A.
Thieringer R, et al. Among authors: le grand cb.
J Immunol. 2001 Jul 1;167(1):30-5. doi: 10.4049/jimmunol.167.1.30.
J Immunol. 2001.
PMID: 11418628
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11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice.
Hermanowski-Vosatka A, Balkovec JM, Cheng K, Chen HY, Hernandez M, Koo GC, Le Grand CB, Li Z, Metzger JM, Mundt SS, Noonan H, Nunes CN, Olson SH, Pikounis B, Ren N, Robertson N, Schaeffer JM, Shah K, Springer MS, Strack AM, Strowski M, Wu K, Wu T, Xiao J, Zhang BB, Wright SD, Thieringer R.
Hermanowski-Vosatka A, et al. Among authors: le grand cb.
J Exp Med. 2005 Aug 15;202(4):517-27. doi: 10.1084/jem.20050119.
J Exp Med. 2005.
PMID: 16103409
Free PMC article.
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Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolysaccharide in vitro or in vivo.
Thieringer R, Fenyk-Melody JE, Le Grand CB, Shelton BA, Detmers PA, Somers EP, Carbin L, Moller DE, Wright SD, Berger J.
Thieringer R, et al. Among authors: le grand cb.
J Immunol. 2000 Jan 15;164(2):1046-54. doi: 10.4049/jimmunol.164.2.1046.
J Immunol. 2000.
PMID: 10623855
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