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Hyaluronan matrix inhibition enhances metabolic anticancer therapy by dichloroacetate in vitro and in vivo.

Twarock S, Reichert C, Bach K, Reiners O, Kretschmer I, Gorski DJ, Gorges K, Grandoch M, Fischer JW.

Br J Pharmacol. 2019 Jul 27. doi: 10.1111/bph.14808. [Epub ahead of print]


The Epidemiology of Cancer Among Homeless Adults in Metropolitan Detroit.

Holowatyj AN, Heath EI, Pappas LM, Ruterbusch JJ, Gorski DH, Triest JA, Park HK, Beebe-Dimmer JL, Schwartz AG, Cote ML, Schwartz KL.

JNCI Cancer Spectr. 2019 Mar;3(1):pkz006. doi: 10.1093/jncics/pkz006. Epub 2019 Mar 25.


Cardiac Hyaluronan Synthesis Is Critically Involved in the Cardiac Macrophage Response and Promotes Healing After Ischemia Reperfusion Injury.

Petz A, Grandoch M, Gorski DJ, Abrams M, Piroth M, Schneckmann R, Homann S, Müller J, Hartwig S, Lehr S, Yamaguchi Y, Wight TN, Gorressen S, Ding Z, Kötter S, Krüger M, Heinen A, Kelm M, Gödecke A, Flögel U, Fischer JW.

Circ Res. 2019 May 10;124(10):1433-1447. doi: 10.1161/CIRCRESAHA.118.313285.


Cardiac fibroblast activation and hyaluronan synthesis in response to hyperglycemia and diet-induced insulin resistance.

Gorski DJ, Petz A, Reichert C, Twarock S, Grandoch M, Fischer JW.

Sci Rep. 2019 Feb 12;9(1):1827. doi: 10.1038/s41598-018-36140-6.


Metabotropic glutamate receptor-1 regulates inflammation in triple negative breast cancer.

Sexton RE, Hachem AH, Assi AA, Bukhsh MA, Gorski DH, Speyer CL.

Sci Rep. 2018 Oct 30;8(1):16008. doi: 10.1038/s41598-018-34502-8.


IgA Fc-folate conjugate activates and recruits neutrophils to directly target triple-negative breast cancer cells.

Frontera ED, Khansa RM, Schalk DL, Leakan LE, Guerin-Edbauer TJ, Ratnam M, Gorski DH, Speyer CL.

Breast Cancer Res Treat. 2018 Dec;172(3):551-560. doi: 10.1007/s10549-018-4941-5. Epub 2018 Aug 28.


Racial Differences in 21-Gene Recurrence Scores Among Patients With Hormone Receptor-Positive, Node-Negative Breast Cancer.

Holowatyj AN, Cote ML, Ruterbusch JJ, Ghanem K, Schwartz AG, Vigneau FD, Gorski DH, Purrington KS.

J Clin Oncol. 2018 Mar 1;36(7):652-658. doi: 10.1200/JCO.2017.74.5448. Epub 2018 Jan 17. Erratum in: J Clin Oncol. 2018 Apr 1;36(10):1054.


Evidence for functional PAR-4 thrombin receptor expression in cardiac fibroblasts and its regulation by high glucose: PAR-4 in cardiac fibroblasts.

Kleeschulte S, Jerrentrup J, Gorski D, Schmitt J, Fender AC.

Int J Cardiol. 2018 Feb 1;252:163-166. doi: 10.1016/j.ijcard.2017.10.019.


Riluzole synergizes with paclitaxel to inhibit cell growth and induce apoptosis in triple-negative breast cancer.

Speyer CL, Bukhsh MA, Jafry WS, Sexton RE, Bandyopadhyay S, Gorski DH.

Breast Cancer Res Treat. 2017 Nov;166(2):407-419. doi: 10.1007/s10549-017-4435-x. Epub 2017 Aug 5.


Hyperglycaemia and aberrated insulin signalling stimulate tumour progression via induction of the extracellular matrix component hyaluronan.

Twarock S, Reichert C, Peters U, Gorski DJ, Röck K, Fischer JW.

Int J Cancer. 2017 Aug 15;141(4):791-804. doi: 10.1002/ijc.30776. Epub 2017 Jun 1.


Variation in the use of advanced imaging at the time of breast cancer diagnosis in a statewide registry.

Henry NL, Braun TM, Breslin TM, Gorski DH, Silver SM, Griggs JJ.

Cancer. 2017 Aug 1;123(15):2975-2983. doi: 10.1002/cncr.30674. Epub 2017 Mar 16.


Degenerative Suspensory Ligament Desmitis (DSLD) in Peruvian Paso Horses Is Characterized by Altered Expression of TGFβ Signaling Components in Adipose-Derived Stromal Fibroblasts.

Luo W, Sandy J, Trella K, Gorski D, Gao S, Li J, Brounts S, Galante J, Plaas A.

PLoS One. 2016 Nov 30;11(11):e0167069. doi: 10.1371/journal.pone.0167069. eCollection 2016.


Associations between use of the 21-gene recurrence score assay and chemotherapy regimen selection in a statewide registry.

Henry NL, Braun TM, Ali HY, Munir K, Silver SM, Gorski DH, Breslin TM, Griggs JJ.

Cancer. 2017 May 15;123(6):948-956. doi: 10.1002/cncr.30429. Epub 2016 Oct 27.


Strategic Endothelial Cell Tube Formation Assay: Comparing Extracellular Matrix and Growth Factor Reduced Extracellular Matrix.

Xie D, Ju D, Speyer C, Gorski D, Kosir MA.

J Vis Exp. 2016 Aug 14;(114). doi: 10.3791/54074.


HER2 status and disparities in luminal breast cancers.

Holowatyj AN, Ruterbusch JJ, Ratnam M, Gorski DH, Cote ML.

Cancer Med. 2016 Aug;5(8):2109-16. doi: 10.1002/cam4.757. Epub 2016 Jun 1.


Riluzole mediates anti-tumor properties in breast cancer cells independent of metabotropic glutamate receptor-1.

Speyer CL, Nassar MA, Hachem AH, Bukhsh MA, Jafry WS, Khansa RM, Gorski DH.

Breast Cancer Res Treat. 2016 Jun;157(2):217-228. doi: 10.1007/s10549-016-3816-x. Epub 2016 May 4.


Trends in Metastatic Breast and Prostate Cancer.

Welch HG, Gorski DH, Albertsen PC.

N Engl J Med. 2016 Feb 11;374(6):596. doi: 10.1056/NEJMc1515983. No abstract available.


Trends in Metastatic Breast and Prostate Cancer--Lessons in Cancer Dynamics.

Welch HG, Gorski DH, Albertsen PC.

N Engl J Med. 2015 Oct 29;373(18):1685-7. doi: 10.1056/NEJMp1510443. No abstract available.


Deletion of ADAMTS5 does not affect aggrecan or versican degradation but promotes glucose uptake and proteoglycan synthesis in murine adipose derived stromal cells.

Gorski DJ, Xiao W, Li J, Luo W, Lauer M, Kisiday J, Plaas A, Sandy J.

Matrix Biol. 2015 Sep;47:66-84. doi: 10.1016/j.matbio.2015.03.008. Epub 2015 Mar 31.


The role of academic health centres to inform evidence-based integrative oncology practice.

Gorski DH.

Nat Rev Cancer. 2015 Apr;15(4):247. doi: 10.1038/nrc3822-c4. No abstract available.


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