Format

Send to

Choose Destination

See 1 citation found by title matching your search:

Cell Death Differ. 2013 Aug;20(8):976-86. doi: 10.1038/cdd.2013.50. Epub 2013 May 24.

Glycobiology of cell death: when glycans and lectins govern cell fate.

Author information

1
Avram and Stella Goren-Goldstein, Department of Biotechnology Engineering, Faculty of Engineering, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

Abstract

Although one typically thinks of carbohydrates as associated with cell growth and viability, glycosylation also has an integral role in many processes leading to cell death. Glycans, either alone or complexed with glycan-binding proteins, can deliver intracellular signals or control extracellular processes that promote initiation, execution and resolution of cell death programs. Herein, we review the role of glycans and glycan-binding proteins as essential components of the cell death machinery during physiologic and pathologic settings.

PMID:
23703323
PMCID:
PMC3705604
DOI:
10.1038/cdd.2013.50
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center