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Items: 1 to 20 of 74


Metabolic derangements of skeletal muscle from a murine model of glioma cachexia.

Cui P, Shao W, Huang C, Wu CJ, Jiang B, Lin D.

Skelet Muscle. 2019 Jan 11;9(1):3. doi: 10.1186/s13395-018-0188-4.


TSPO-PET imaging using [18F]PBR06 is a potential translatable biomarker for treatment response in Huntington's disease: preclinical evidence with the p75NTR ligand LM11A-31.

Simmons DA, James ML, Belichenko NP, Semaan S, Condon C, Kuan J, Shuhendler AJ, Miao Z, Chin FT, Longo FM.

Hum Mol Genet. 2018 Aug 15;27(16):2893-2912. doi: 10.1093/hmg/ddy202.


Neuronal glucose metabolism is impaired while astrocytic TCA cycling is unaffected at symptomatic stages in the hSOD1G93A mouse model of amyotrophic lateral sclerosis.

Tefera TW, Borges K.

J Cereb Blood Flow Metab. 2019 Sep;39(9):1710-1724. doi: 10.1177/0271678X18764775. Epub 2018 Mar 19.


Cyclophilin inhibitor NIM811 ameliorates experimental allergic encephalomyelitis.

Huang ZL, Pandya D, Banta DK, Ansari MS, Oh U.

J Neuroimmunol. 2017 Oct 15;311:40-48. doi: 10.1016/j.jneuroim.2017.07.016. Epub 2017 Aug 2.


Noncovalent Bonding of RGD and YIGSR to an Electrospun Poly(ε-Caprolactone) Conduit through Peptide Self-Assembly to Synergistically Promote Sciatic Nerve Regeneration in Rats.

Zhu L, Wang K, Ma T, Huang L, Xia B, Zhu S, Yang Y, Liu Z, Quan X, Luo K, Kong D, Huang J, Luo Z.

Adv Healthc Mater. 2017 Apr;6(8). doi: 10.1002/adhm.201600860. Epub 2017 Jan 31.


Time-Dependent Lactate Production and Amino Acid Utilization in Cultured Astrocytes Under High Glucose Exposure.

Wang D, Zhao L, Zheng H, Dong M, Pan L, Zhang X, Zhang H, Gao H.

Mol Neurobiol. 2018 Feb;55(2):1112-1122. doi: 10.1007/s12035-016-0360-y. Epub 2017 Jan 16.


Late-onset episodic ataxia associated with SLC1A3 mutation.

Choi KD, Jen JC, Choi SY, Shin JH, Kim HS, Kim HJ, Kim JS, Choi JH.

J Hum Genet. 2017 Mar;62(3):443-446. doi: 10.1038/jhg.2016.137. Epub 2016 Nov 10.


Severity of experimental traumatic brain injury modulates changes in concentrations of cerebral free amino acids.

Amorini AM, Lazzarino G, Di Pietro V, Signoretti S, Lazzarino G, Belli A, Tavazzi B.

J Cell Mol Med. 2017 Mar;21(3):530-542. doi: 10.1111/jcmm.12998. Epub 2016 Oct 3.


Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder.

Jones JM, Dionne L, Dell'Orco J, Parent R, Krueger JN, Cheng X, Dib-Hajj SD, Bunton-Stasyshyn RK, Sharkey LM, Dowling JJ, Murphy GG, Shakkottai VG, Shrager P, Meisler MH.

Neurobiol Dis. 2016 May;89:36-45. doi: 10.1016/j.nbd.2016.01.018. Epub 2016 Jan 22.


Self-Assembling Peptide Nanofiber Containing Long Motif of Laminin Induces Neural Differentiation, Tubulin Polymerization, and Neurogenesis: In Vitro, Ex Vivo, and In Vivo Studies.

Tavakol S, Saber R, Hoveizi E, Tavakol B, Aligholi H, Ai J, Rezayat SM.

Mol Neurobiol. 2016 Oct;53(8):5288-99. doi: 10.1007/s12035-015-9448-z. Epub 2015 Oct 1.


Novel p75 neurotrophin receptor ligand stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV associated neuropathogenesis.

Meeker RB, Poulton W, Clary G, Schriver M, Longo FM.

Exp Neurol. 2016 Jan;275 Pt 1:182-98. doi: 10.1016/j.expneurol.2015.09.012. Epub 2015 Sep 28.


Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.

Castel D, Philippe C, Calmon R, Le Dret L, Truffaux N, Boddaert N, Pagès M, Taylor KR, Saulnier P, Lacroix L, Mackay A, Jones C, Sainte-Rose C, Blauwblomme T, Andreiuolo F, Puget S, Grill J, Varlet P, Debily MA.

Acta Neuropathol. 2015 Dec;130(6):815-27. doi: 10.1007/s00401-015-1478-0. Epub 2015 Sep 23.


Dysfunctional TCA-Cycle Metabolism in Glutamate Dehydrogenase Deficient Astrocytes.

Nissen JD, Pajęcka K, Stridh MH, Skytt DM, Waagepetersen HS.

Glia. 2015 Dec;63(12):2313-26. doi: 10.1002/glia.22895. Epub 2015 Jul 29.


Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice.

Nguyen TV, Shen L, Vander Griend L, Quach LN, Belichenko NP, Saw N, Yang T, Shamloo M, Wyss-Coray T, Massa SM, Longo FM.

J Alzheimers Dis. 2014;42(2):459-83. doi: 10.3233/JAD-140036.


Design and synthesis of elastin-like polypeptides for an ideal nerve conduit in peripheral nerve regeneration.

Hsueh YS, Savitha S, Sadhasivam S, Lin FH, Shieh MJ.

Mater Sci Eng C Mater Biol Appl. 2014 May 1;38:119-26. doi: 10.1016/j.msec.2014.01.058. Epub 2014 Feb 6.


Branched-chain amino acids influence the immune properties of microglial cells and their responsiveness to pro-inflammatory signals.

De Simone R, Vissicchio F, Mingarelli C, De Nuccio C, Visentin S, Ajmone-Cat MA, Minghetti L.

Biochim Biophys Acta. 2013 May;1832(5):650-9. doi: 10.1016/j.bbadis.2013.02.001. Epub 2013 Feb 9.


Role of branched chain amino acids in cerebral ammonia homeostasis related to hepatic encephalopathy.

Bak LK, Waagepetersen HS, Sørensen M, Ott P, Vilstrup H, Keiding S, Schousboe A.

Metab Brain Dis. 2013 Jun;28(2):209-15. doi: 10.1007/s11011-013-9381-7. Epub 2013 Jan 31. Review.


Oral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after spinal cord injury.

Tep C, Lim TH, Ko PO, Getahun S, Ryu JC, Goettl VM, Massa SM, Basso M, Longo FM, Yoon SO.

J Neurosci. 2013 Jan 9;33(2):397-410. doi: 10.1523/JNEUROSCI.0399-12.2013. Erratum in: J Neurosci. 2014 Jan 29;34(5):2012.


Borna disease virus infection perturbs energy metabolites and amino acids in cultured human oligodendroglia cells.

Huang R, Gao H, Zhang L, Jia J, Liu X, Zheng P, Ma L, Li W, Deng J, Wang X, Yang L, Wang M, Xie P.

PLoS One. 2012;7(9):e44665. doi: 10.1371/journal.pone.0044665. Epub 2012 Sep 7.


Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models.

Algarzae N, Hebron M, Miessau M, Moussa CE.

Neuroscience. 2012 Dec 6;225:22-34. doi: 10.1016/j.neuroscience.2012.08.057. Epub 2012 Sep 6.

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