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2014 | 3 |
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GTP-binding facilitates EB1 recruitment onto microtubules by relieving its auto-inhibition.
Sci Rep. 2018 Jun 28;8(1):9792. doi: 10.1038/s41598-018-28056-y.
Sci Rep. 2018.
PMID: 29955158
Free PMC article.
TACC3 protein regulates microtubule nucleation by affecting γ-tubulin ring complexes.
Singh P, Thomas GE, Gireesh KK, Manna TK.
Singh P, et al. Among authors: gireesh kk.
J Biol Chem. 2014 Nov 14;289(46):31719-31735. doi: 10.1074/jbc.M114.575100. Epub 2014 Sep 22.
J Biol Chem. 2014.
PMID: 25246530
Free PMC article.
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EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice.
Thomas GE, Bandopadhyay K, Sutradhar S, Renjith MR, Singh P, Gireesh KK, Simon S, Badarudeen B, Gupta H, Banerjee M, Paul R, Mitra J, Manna TK.
Thomas GE, et al. Among authors: gireesh kk.
Nat Commun. 2016 May 26;7:11665. doi: 10.1038/ncomms11665.
Nat Commun. 2016.
PMID: 27225956
Free PMC article.
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+TIP EB1 downregulates paclitaxel‑induced proliferation inhibition and apoptosis in breast cancer cells through inhibition of paclitaxel binding on microtubules.
Thomas GE, Sreeja JS, Gireesh KK, Gupta H, Manna TK.
Thomas GE, et al. Among authors: gireesh kk.
Int J Oncol. 2015 Jan;46(1):133-46. doi: 10.3892/ijo.2014.2701. Epub 2014 Oct 7.
Int J Oncol. 2015.
PMID: 25310526
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Human SAS-6 C-Terminus Nucleates and Promotes Microtubule Assembly in Vitro by Binding to Microtubules.
Gupta H, Badarudeen B, George A, Thomas GE, Gireesh KK, Manna TK.
Gupta H, et al. Among authors: gireesh kk.
Biochemistry. 2015 Oct 20;54(41):6413-22. doi: 10.1021/acs.biochem.5b00978. Epub 2015 Oct 7.
Biochemistry. 2015.
PMID: 26422590
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CIL-102 binds to tubulin at colchicine binding site and triggers apoptosis in MCF-7 cells by inducing monopolar and multinucleated cells.
Gireesh KK, Rashid A, Chakraborti S, Panda D, Manna T.
Gireesh KK, et al.
Biochem Pharmacol. 2012 Sep 1;84(5):633-45. doi: 10.1016/j.bcp.2012.06.008. Epub 2012 Jun 15.
Biochem Pharmacol. 2012.
PMID: 22705644
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Microtubule +TIP protein EB1 binds to GTP and undergoes dissociation from dimer to monomer on binding GTP.
Gireesh KK, Sreeja JS, Chakraborti S, Singh P, Thomas GE, Gupta H, Manna T.
Gireesh KK, et al.
Biochemistry. 2014 Sep 2;53(34):5551-7. doi: 10.1021/bi5007942. Epub 2014 Aug 21.
Biochemistry. 2014.
PMID: 25111064
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