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Items: 1 to 20 of 321

1.

A Third Shot at EGFR: New Opportunities in Cancer Therapy.

Guardiola S, Varese M, Sánchez-Navarro M, Giralt E.

Trends Pharmacol Sci. 2019 Dec;40(12):941-955. doi: 10.1016/j.tips.2019.10.004. Epub 2019 Nov 6. Review.

PMID:
31706618
2.

Trimeric heptad repeat synthetic peptides HR1 and HR2 efficiently inhibit HIV-1 entry.

Mzoughi O, Teixido M, Planès R, Serrero M, Hamimed I, Zurita E, Moreno M, Granados G, Lakhdar-Ghazal F, BenMohamed L, Giralt E, Bahraoui E.

Biosci Rep. 2019 Sep 24;39(9). pii: BSR20192196. doi: 10.1042/BSR20192196. Print 2019 Sep 30.

3.

Protein Chemical Synthesis Combined with Mirror-Image Phage Display Yields d-Peptide EGF Ligands that Block the EGF-EGFR Interaction.

Díaz-Perlas C, Varese M, Guardiola S, Sánchez-Navarro M, García J, Teixidó M, Giralt E.

Chembiochem. 2019 Aug 16;20(16):2079-2084. doi: 10.1002/cbic.201900355. Epub 2019 Jul 22.

PMID:
31268623
4.

Enthalpy- versus Entropy-Driven Molecular Recognition in the Era of Biologics.

Varese M, Guardiola S, García J, Giralt E.

Chembiochem. 2019 Jun 3. doi: 10.1002/cbic.201900270. [Epub ahead of print]

PMID:
31157491
5.

Sphenopalatine Ganglion Stimulation to Augment Cerebral Blood Flow.

Bornstein NM, Saver JL, Diener HC, Gorelick PB, Shuaib A, Solberg Y, Devlin T, Leung T, Molina CA; ImpACT-24A Investigators † ; ImpACT-24A Investigators include the Site Principal Investigators, DSMB members, and the Site Co-Investigators listed.

Stroke. 2019 May 23:STROKEAHA118024582. doi: 10.1161/STROKEAHA.118.024582. [Epub ahead of print]

PMID:
31117920
6.

Expanding the MiniAp-4 BBB-shuttle family: Evaluation of proline cis-trans ratio as tool to fine-tune transport.

Fuster C, Varese M, García J, Giralt E, Sánchez-Navarro M, Teixidó M.

J Pept Sci. 2019 May;25(5):e3172. doi: 10.1002/psc.3172.

PMID:
31006945
7.

Algorithm-supported, mass and sequence diversity-oriented random peptide library design.

Kalafatovic D, Mauša G, Todorovski T, Giralt E.

J Cheminform. 2019 Mar 28;11(1):25. doi: 10.1186/s13321-019-0347-6.

8.

A MALDI-TOF-based Method for Studying the Transport of BBB Shuttles-Enhancing Sensitivity and Versatility of Cell-Based In Vitro Transport Models.

Arranz-Gibert P, Guixer B, Prades R, Ciudad S, Giralt E, Teixidó M.

Sci Rep. 2019 Mar 19;9(1):4875. doi: 10.1038/s41598-019-40973-0.

9.

Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation.

Villoslada P, Vila G, Colafrancesco V, Moreno B, Fernandez-Diez B, Vazquez R, Pertsovskaya I, Zubizarreta I, Pulido-Valdeolivas I, Messeguer J, Vendrell-Navarro G, Frade JM, López-Sánchez N, Teixido M, Giralt E, Masso M, Dugas JC, Leonoudakis D, Lariosa-Willingham KD, Steinman L, Messeguer A.

Neurotherapeutics. 2019 Jul;16(3):808-827. doi: 10.1007/s13311-019-00717-4.

PMID:
30815844
10.

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.

Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]

11.

HAI Peptide and Backbone Analogs-Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles.

Arranz-Gibert P, Prades R, Guixer B, Guerrero S, Araya E, Ciudad S, Kogan MJ, Giralt E, Teixidó M.

Sci Rep. 2018 Dec 18;8(1):17932. doi: 10.1038/s41598-018-35938-8.

12.

Branched BBB-shuttle peptides: chemoselective modification of proteins to enhance blood-brain barrier transport.

Díaz-Perlas C, Oller-Salvia B, Sánchez-Navarro M, Teixidó M, Giralt E.

Chem Sci. 2018 Sep 18;9(44):8409-8415. doi: 10.1039/c8sc02415d. eCollection 2018 Nov 28.

13.

Targeted Nanoswitchable Inhibitors of Protein-Protein Interactions Involved in Apoptosis.

Nevola L, Varese M, Martín-Quirós A, Mari G, Eckelt K, Gorostiza P, Giralt E.

ChemMedChem. 2019 Jan 8;14(1):100-106. doi: 10.1002/cmdc.201800647. Epub 2018 Dec 10.

PMID:
30380184
14.

From venoms to BBB-shuttles. MiniCTX3: a molecular vector derived from scorpion venom.

Díaz-Perlas C, Varese M, Guardiola S, García J, Sánchez-Navarro M, Giralt E, Teixidó M.

Chem Commun (Camb). 2018 Nov 8;54(90):12738-12741. doi: 10.1039/c8cc06725b.

PMID:
30357254
15.

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.

Kasner SE, Swaminathan B, Lavados P, Sharma M, Muir K, Veltkamp R, Ameriso SF, Endres M, Lutsep H, Messé SR, Spence JD, Nedeltechev K, Perera K, Santo G, Olavarria V, Lindgren A, Bangdiwala S, Shoamanesh A, Berkowitz SD, Mundl H, Connolly SJ, Hart RG; NAVIGATE ESUS Investigators.

Lancet Neurol. 2018 Dec;17(12):1053-1060. doi: 10.1016/S1474-4422(18)30319-3. Epub 2018 Sep 28. Erratum in: Lancet Neurol. 2018 Oct 23;:.

16.

Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.

Pujols J, Peña-Díaz S, Lázaro DF, Peccati F, Pinheiro F, González D, Carija A, Navarro S, Conde-Giménez M, García J, Guardiola S, Giralt E, Salvatella X, Sancho J, Sodupe M, Outeiro TF, Dalfó E, Ventura S.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486. doi: 10.1073/pnas.1804198115. Epub 2018 Sep 24.

17.

Synergistic activity of an OmpA inhibitor and colistin against colistin-resistant Acinetobacter baumannii: mechanistic analysis and in vivo efficacy.

Parra-Millán R, Vila-Farrés X, Ayerbe-Algaba R, Varese M, Sánchez-Encinales V, Bayó N, Pachón-Ibáñez ME, Teixidó M, Vila J, Pachón J, Giralt E, Smani Y.

J Antimicrob Chemother. 2018 Dec 1;73(12):3405-3412. doi: 10.1093/jac/dky343.

PMID:
30188994
18.

Blocking EGFR Activation with Anti-EGF Nanobodies via Two Distinct Molecular Recognition Mechanisms.

Guardiola S, Varese M, Sánchez-Navarro M, Vincke C, Teixidó M, García J, Muyldermans S, Giralt E.

Angew Chem Int Ed Engl. 2018 Oct 15;57(42):13843-13847. doi: 10.1002/anie.201807736. Epub 2018 Sep 21.

PMID:
30152597
19.

d-Polyarginine Lipopeptides as Intestinal Permeation Enhancers.

Garcia J, Fernández-Blanco Á, Teixidó M, Sánchez-Navarro M, Giralt E.

ChemMedChem. 2018 Oct 8;13(19):2045-2052. doi: 10.1002/cmdc.201800428. Epub 2018 Aug 20.

PMID:
30063113
20.

Severity of allergic rhinitis impacts sleep and anxiety: results from a large Spanish cohort.

Muñoz-Cano R, Ribó P, Araujo G, Giralt E, Sanchez-Lopez J, Valero A.

Clin Transl Allergy. 2018 Jul 9;8:23. doi: 10.1186/s13601-018-0212-0. eCollection 2018.

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