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Items: 1 to 20 of 40

1.

Reducing age-dependent monocyte-derived macrophage activation contributes to the therapeutic efficacy of NADPH oxidase inhibition in spinal cord injury.

Zhang B, Bailey WM, McVicar AL, Stewart AN, Veldhorst AK, Gensel JC.

Brain Behav Immun. 2018 Nov 16. pii: S0889-1591(18)30342-8. doi: 10.1016/j.bbi.2018.11.013. [Epub ahead of print]

2.

Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion.

Davis SM, Collier LA, Winford ED, Leonardo CC, Ajmo CT Jr, Foran EA, Kopper TJ, Gensel JC, Pennypacker KR.

J Neuroinflammation. 2018 Oct 15;15(1):288. doi: 10.1186/s12974-018-1326-y.

3.

Azithromycin therapy reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction: Potential therapeutic targets in ischemic heart disease.

Al-Darraji A, Haydar D, Chelvarajan L, Tripathi H, Levitan B, Gao E, Venditto VJ, Gensel JC, Feola DJ, Abdel-Latif A.

PLoS One. 2018 Jul 12;13(7):e0200474. doi: 10.1371/journal.pone.0200474. eCollection 2018.

4.

Spinal Cord Injury Scarring and Inflammation: Therapies Targeting Glial and Inflammatory Responses.

Orr MB, Gensel JC.

Neurotherapeutics. 2018 Jul;15(3):541-553. doi: 10.1007/s13311-018-0631-6. Review.

PMID:
29717413
5.

Interactions of primary insult biomechanics and secondary cascades in spinal cord injury: implications for therapy.

Orr MB, Gensel JC.

Neural Regen Res. 2017 Oct;12(10):1618-1619. doi: 10.4103/1673-5374.217332. No abstract available.

6.

Stress Increases Peripheral Axon Growth and Regeneration through Glucocorticoid Receptor-Dependent Transcriptional Programs.

Lerch JK, Alexander JK, Madalena KM, Motti D, Quach T, Dhamija A, Zha A, Gensel JC, Webster Marketon J, Lemmon VP, Bixby JL, Popovich PG.

eNeuro. 2017 Aug 21;4(4). pii: ENEURO.0246-17.2017. doi: 10.1523/ENEURO.0246-17.2017. eCollection 2017 Jul-Aug.

7.

Myelin as an inflammatory mediator: Myelin interactions with complement, macrophages, and microglia in spinal cord injury.

Kopper TJ, Gensel JC.

J Neurosci Res. 2018 Jun;96(6):969-977. doi: 10.1002/jnr.24114. Epub 2017 Jul 11. Review.

8.

Macrophages are necessary for epimorphic regeneration in African spiny mice.

Simkin J, Gawriluk TR, Gensel JC, Seifert AW.

Elife. 2017 May 16;6. pii: e24623. doi: 10.7554/eLife.24623.

9.

Compression Decreases Anatomical and Functional Recovery and Alters Inflammation after Contusive Spinal Cord Injury.

Orr MB, Simkin J, Bailey WM, Kadambi NS, McVicar AL, Veldhorst AK, Gensel JC.

J Neurotrauma. 2017 Aug 1;34(15):2342-2352. doi: 10.1089/neu.2016.4915. Epub 2017 Jun 14.

10.

Pioglitazone treatment following spinal cord injury maintains acute mitochondrial integrity and increases chronic tissue sparing and functional recovery.

Patel SP, Cox DH, Gollihue JL, Bailey WM, Geldenhuys WJ, Gensel JC, Sullivan PG, Rabchevsky AG.

Exp Neurol. 2017 Jul;293:74-82. doi: 10.1016/j.expneurol.2017.03.021. Epub 2017 Mar 30.

11.

Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment.

Gensel JC, Kopper TJ, Zhang B, Orr MB, Bailey WM.

Sci Rep. 2017 Jan 6;7:40144. doi: 10.1038/srep40144.

12.

Age increases reactive oxygen species production in macrophages and potentiates oxidative damage after spinal cord injury.

Zhang B, Bailey WM, McVicar AL, Gensel JC.

Neurobiol Aging. 2016 Nov;47:157-167. doi: 10.1016/j.neurobiolaging.2016.07.029. Epub 2016 Aug 6.

13.

Cardiac Chemical Exchange Saturation Transfer MR Imaging Tracking of Cell Survival or Rejection in Mouse Models of Cell Therapy.

Pumphrey AL, Ye S, Yang Z, Simkin J, Gensel JC, Abdel-Latif A, Vandsburger MH.

Radiology. 2017 Jan;282(1):131-138. doi: 10.1148/radiol.2016152766. Epub 2016 Jul 15.

14.

CNS Plasticity in Injury and Disease.

Miller BA, Gensel JC, Beattie MS.

Neural Plast. 2016;2016:1923950. doi: 10.1155/2016/1923950. Epub 2016 Jan 10. No abstract available.

15.

Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury.

Zhang B, Bailey WM, Kopper TJ, Orr MB, Feola DJ, Gensel JC.

J Neuroinflammation. 2015 Nov 24;12:218. doi: 10.1186/s12974-015-0440-3.

16.

Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury.

Nielson JL, Paquette J, Liu AW, Guandique CF, Tovar CA, Inoue T, Irvine KA, Gensel JC, Kloke J, Petrossian TC, Lum PY, Carlsson GE, Manley GT, Young W, Beattie MS, Bresnahan JC, Ferguson AR.

Nat Commun. 2015 Oct 14;6:8581. doi: 10.1038/ncomms9581.

17.

Identification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimer's Disease Brain.

Meier S, Bell M, Lyons DN, Ingram A, Chen J, Gensel JC, Zhu H, Nelson PT, Abisambra JF.

J Alzheimers Dis. 2015;48(3):687-702. doi: 10.3233/JAD-150298.

18.

Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury.

Zhang B, Bailey WM, Braun KJ, Gensel JC.

Exp Neurol. 2015 Nov;273:83-91. doi: 10.1016/j.expneurol.2015.08.001. Epub 2015 Aug 8.

19.

Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages.

Gensel JC, Wang Y, Guan Z, Beckwith KA, Braun KJ, Wei P, McTigue DM, Popovich PG.

J Neurosci. 2015 Jul 8;35(27):9966-76. doi: 10.1523/JNEUROSCI.0337-15.2015.

20.

Stress exacerbates neuron loss and microglia proliferation in a rat model of excitotoxic lower motor neuron injury.

Puga DA, Tovar CA, Guan Z, Gensel JC, Lyman MS, McTigue DM, Popovich PG.

Brain Behav Immun. 2015 Oct;49:246-54. doi: 10.1016/j.bbi.2015.06.006. Epub 2015 Jun 19.

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