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Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.
Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, McCarty CA, Chisholm RL, Kho AN, Carlson CS, Larson EB, Jarvik GP, Sotoodehnia N; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) QRS Group; Manolio TA, Li R, Masys DR, Haines JL, Roden DM. Ritchie MD, et al. Circulation. 2013 Apr 2;127(13):1377-85. doi: 10.1161/CIRCULATIONAHA.112.000604. Epub 2013 Mar 5. Circulation. 2013. PMID: 23463857 Free PMC article. Clinical Trial.
Slow conduction may promote re-entrant arrhythmias. METHODS AND RESULTS: We performed a genome-wide association study to identify genomic markers of QRS duration in 5272 individuals without cardiac disease selected from electronic …
Slow conduction may promote re-entrant arrhythmias. METHODS AND RESULTS: We performed a genome-wide association study t …
Epigenome-wide association study of diabetic chronic kidney disease progression in the Korean population: the KNOW-CKD study.
Sung HY, Lee S, Han M, An WJ, Ryu H, Kang E, Park YS, Lee SE, Ahn C, Oh KH, Park SK, Ahn JH. Sung HY, et al. Sci Rep. 2023 May 20;13(1):8175. doi: 10.1038/s41598-023-35485-x. Sci Rep. 2023. PMID: 37210443 Free PMC article.
A phenome-wide association study was performed to determine the associations between CpG sites and other phenotypes. ...Based on the functional analyses, other phenotypes (blood pressure and cardiac arrhythmia for AGTR1) and biological pathways …
A phenome-wide association study was performed to determine the associations between CpG sites and other phenotypes. ...Based …