Send to

Choose Destination

See 1 citation found by title matching your search:

Pharmacopsychiatry. 2007 Dec;40 Suppl 1:S73-7. doi: 10.1055/s-2007-992130.

Gating deficits in model networks: a path to schizophrenia?

Author information

Department of Physiology and Cellular Biophysics, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York 10032-2695, USA.


Gating deficits and hallucinatory sensations are prominent symptoms of schizophrenia. Comparing these abnormalities with the failure modes of network models is an interesting way to explore how they arise. We present a network model that can both propagate and gate signals. The model exhibits effects reminiscent of clinically observed pathologies when the balance between excitation and inhibition that it requires is not properly maintained.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Georg Thieme Verlag Stuttgart, New York
Loading ...
Support Center