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Items: 15


Frontline Science: Rapid adipose tissue expansion triggers unique proliferation and lipid accumulation profiles in adipose tissue macrophages.

Muir LA, Kiridena S, Griffin C, DelProposto JB, Geletka L, Martinez-Santibañez G, Zamarron BF, Lucas H, Singer K, O' Rourke RW, Lumeng CN.

J Leukoc Biol. 2018 Apr;103(4):615-628. doi: 10.1002/JLB.3HI1017-422R. Epub 2018 Mar 1.


The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice.

Soofi A, Wolf KI, Emont MP, Qi N, Martinez-Santibanez G, Grimley E, Ostwani W, Dressler GR.

J Biol Chem. 2017 Jun 2;292(22):9051-9062. doi: 10.1074/jbc.M116.771428. Epub 2017 Apr 19.


Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice.

Zamarron BF, Mergian TA, Cho KW, Martinez-Santibanez G, Luan D, Singer K, DelProposto JL, Geletka LM, Muir LA, Lumeng CN.

Diabetes. 2017 Feb;66(2):392-406. doi: 10.2337/db16-0500. Epub 2016 Nov 8.


Adipose tissue fibrosis, hypertrophy, and hyperplasia: Correlations with diabetes in human obesity.

Muir LA, Neeley CK, Meyer KA, Baker NA, Brosius AM, Washabaugh AR, Varban OA, Finks JF, Zamarron BF, Flesher CG, Chang JS, DelProposto JB, Geletka L, Martinez-Santibanez G, Kaciroti N, Lumeng CN, O'Rourke RW.

Obesity (Silver Spring). 2016 Mar;24(3):597-605. doi: 10.1002/oby.21377.


Obesity-induced remodeling of the adipose tissue elastin network is independent of the metalloelastase MMP-12.

Martinez-Santibanez G, Singer K, Cho KW, DelProposto JL, Mergian T, Lumeng CN.

Adipocyte. 2015 Apr 20;4(4):264-72. doi: 10.1080/21623945.2015.1027848. eCollection 2015 Oct-Dec.


Differences in Hematopoietic Stem Cells Contribute to Sexually Dimorphic Inflammatory Responses to High Fat Diet-induced Obesity.

Singer K, Maley N, Mergian T, DelProposto J, Cho KW, Zamarron BF, Martinez-Santibanez G, Geletka L, Muir L, Wachowiak P, Demirjian C, Lumeng CN.

J Biol Chem. 2015 May 22;290(21):13250-62. doi: 10.1074/jbc.M114.634568. Epub 2015 Apr 13.


An MHC II-dependent activation loop between adipose tissue macrophages and CD4+ T cells controls obesity-induced inflammation.

Cho KW, Morris DL, DelProposto JL, Geletka L, Zamarron B, Martinez-Santibanez G, Meyer KA, Singer K, O'Rourke RW, Lumeng CN.

Cell Rep. 2014 Oct 23;9(2):605-17. doi: 10.1016/j.celrep.2014.09.004. Epub 2014 Oct 9.


Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells.

Singer K, DelProposto J, Morris DL, Zamarron B, Mergian T, Maley N, Cho KW, Geletka L, Subbaiah P, Muir L, Martinez-Santibanez G, Lumeng CN.

Mol Metab. 2014 Jul 10;3(6):664-75. doi: 10.1016/j.molmet.2014.06.005. eCollection 2014 Sep.


Imaging white adipose tissue with confocal microscopy.

Martinez-Santibañez G, Cho KW, Lumeng CN.

Methods Enzymol. 2014;537:17-30. doi: 10.1016/B978-0-12-411619-1.00002-1. Review.


Thrombospondin 1 mediates high-fat diet-induced muscle fibrosis and insulin resistance in male mice.

Inoue M, Jiang Y, Barnes RH 2nd, Tokunaga M, Martinez-Santibañez G, Geletka L, Lumeng CN, Buchner DA, Chun TH.

Endocrinology. 2013 Dec;154(12):4548-59. doi: 10.1210/en.2013-1587. Epub 2013 Oct 18.


Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice.

Morris DL, Cho KW, Delproposto JL, Oatmen KE, Geletka LM, Martinez-Santibanez G, Singer K, Lumeng CN.

Diabetes. 2013 Aug;62(8):2762-72. doi: 10.2337/db12-1404. Epub 2013 Mar 14.


Macrophages and the regulation of adipose tissue remodeling.

Martinez-Santibañez G, Lumeng CN.

Annu Rev Nutr. 2014;34:57-76. doi: 10.1146/annurev-nutr-071812-161113. Epub 2014 May 14. Review.


Aging is associated with an increase in T cells and inflammatory macrophages in visceral adipose tissue.

Lumeng CN, Liu J, Geletka L, Delaney C, Delproposto J, Desai A, Oatmen K, Martinez-Santibanez G, Julius A, Garg S, Yung RL.

J Immunol. 2011 Dec 15;187(12):6208-16. doi: 10.4049/jimmunol.1102188. Epub 2011 Nov 9.


Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism.

Cawthorn WP, Bree AJ, Yao Y, Du B, Hemati N, Martinez-Santibañez G, MacDougald OA.

Bone. 2012 Feb;50(2):477-89. doi: 10.1016/j.bone.2011.08.010. Epub 2011 Aug 18.


An up-close look at the pre-mRNA 3'-end processing complex.

Shi Y, Chan S, Martinez-Santibañez G.

RNA Biol. 2009 Nov-Dec;6(5):522-5. Epub 2009 Nov 18. Review.


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