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Items: 15

1.

Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.

Coussens NP, Sittampalam GS, Guha R, Brimacombe K, Grossman A, Chung TDY, Weidner JR, Riss T, Trask OJ, Auld D, Dahlin JL, Devanaryan V, Foley TL, McGee J, Kahl SD, Kales SC, Arkin M, Baell J, Bejcek B, Gal-Edd N, Glicksman M, Haas JV, Iversen PW, Hoeppner M, Lathrop S, Sayers E, Liu H, Trawick B, McVey J, Lemmon VP, Li Z, McManus O, Minor L, Napper A, Wildey MJ, Pacifici R, Chin WW, Xia M, Xu X, Lal-Nag M, Hall MD, Michael S, Inglese J, Simeonov A, Austin CP.

Clin Transl Sci. 2018 Sep;11(5):461-470. doi: 10.1111/cts.12570. Epub 2018 Jul 24.

2.

Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs.

Coussens NP, Braisted JC, Peryea T, Sittampalam GS, Simeonov A, Hall MD.

Pharmacol Rev. 2017 Oct;69(4):479-496. doi: 10.1124/pr.117.013755. Review.

3.

The translational science training program at NIH: Introducing early career researchers to the science and operation of translation of basic research to medical interventions.

Gilliland CT, Sittampalam GS, Wang PY, Ryan PE.

Biochem Mol Biol Educ. 2017 Jan 2;45(1):13-24. doi: 10.1002/bmb.20978. Epub 2016 May 26.

4.

Basics of Assay Equipment and Instrumentation for High Throughput Screening.

Jones E, Michael S, Sittampalam GS.

In: Sittampalam GS, Coussens NP, Brimacombe K, Grossman A, Arkin M, Auld D, Austin C, Baell J, Bejcek B, Caaveiro JMM, Chung TDY, Dahlin JL, Devanaryan V, Foley TL, Glicksman M, Hall MD, Haas JV, Inglese J, Iversen PW, Kahl SD, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Trask OJ Jr., Weidner JR, Wildey MJ, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
2012 May 1 [updated 2016 Apr 2].

5.

Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays.

Lee JA, Shinn P, Jaken S, Oliver S, Willard FS, Heidler S, Peery RB, Oler J, Chu S, Southall N, Dexheimer TS, Smallwood J, Huang R, Guha R, Jadhav A, Cox K, Austin CP, Simeonov A, Sittampalam GS, Husain S, Franklin N, Wild DJ, Yang JJ, Sutherland JJ, Thomas CJ.

PLoS One. 2015 Jul 15;10(7):e0130796. doi: 10.1371/journal.pone.0130796. eCollection 2015.

6.

Phospho-ERK Assays.

Garbison KE, Heinz BA, Lajiness ME, Weidner JR, Sittampalam GS.

In: Sittampalam GS, Coussens NP, Brimacombe K, Grossman A, Arkin M, Auld D, Austin C, Baell J, Bejcek B, Caaveiro JMM, Chung TDY, Dahlin JL, Devanaryan V, Foley TL, Glicksman M, Hall MD, Haas JV, Inglese J, Iversen PW, Kahl SD, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Trask OJ Jr., Weidner JR, Wildey MJ, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
2012 May 1 [updated 2015 Jun 25].

7.

Replication attempt: "Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival".

Iorns E, Gunn W, Erath J, Rodriguez A, Zhou J, Benzinou M; Reproducibility Initiative.

PLoS One. 2014 Dec 17;9(12):e114614. doi: 10.1371/journal.pone.0114614. eCollection 2014.

8.

Calculations and Instrumentation used for Radioligand Binding Assays.

Kahl SD, Sittampalam GS, Weidner J.

In: Sittampalam GS, Coussens NP, Brimacombe K, Grossman A, Arkin M, Auld D, Austin C, Baell J, Bejcek B, Caaveiro JMM, Chung TDY, Dahlin JL, Devanaryan V, Foley TL, Glicksman M, Hall MD, Haas JV, Inglese J, Iversen PW, Kahl SD, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Trask OJ Jr., Weidner JR, Wildey MJ, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-. No abstract available.
2012 May 1 [updated 2012 Oct 1].

9.

HTS Assay Validation.

Iversen PW, Beck B, Chen YF, Dere W, Devanarayan V, Eastwood BJ, Farmen MW, Iturria SJ, Montrose C, Moore RA, Weidner JR, Sittampalam GS.

In: Sittampalam GS, Coussens NP, Brimacombe K, Grossman A, Arkin M, Auld D, Austin C, Baell J, Bejcek B, Caaveiro JMM, Chung TDY, Dahlin JL, Devanaryan V, Foley TL, Glicksman M, Hall MD, Haas JV, Inglese J, Iversen PW, Kahl SD, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Trask OJ Jr., Weidner JR, Wildey MJ, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
2012 May 1 [updated 2012 Oct 1].

10.

Impedance-Based Technologies.

Garbison KE, Heinz BA, Lajiness ME, Weidner JR, Sittampalam GS.

In: Sittampalam GS, Coussens NP, Brimacombe K, Grossman A, Arkin M, Auld D, Austin C, Baell J, Bejcek B, Caaveiro JMM, Chung TDY, Dahlin JL, Devanaryan V, Foley TL, Glicksman M, Hall MD, Haas JV, Inglese J, Iversen PW, Kahl SD, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Trask OJ Jr., Weidner JR, Wildey MJ, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
2012 May 1.

11.

Stretching mechanotransduction from the lung to the lab: approaches and physiological relevance in drug discovery.

Schmitt S, Hendricks P, Weir J, Somasundaram R, Sittampalam GS, Nirmalanandhan VS.

Assay Drug Dev Technol. 2012 Apr;10(2):137-47. doi: 10.1089/adt.2011.418. Epub 2012 Feb 21. Review.

PMID:
22352900
12.

Impact of high-throughput screening in biomedical research.

Macarron R, Banks MN, Bojanic D, Burns DJ, Cirovic DA, Garyantes T, Green DV, Hertzberg RP, Janzen WP, Paslay JW, Schopfer U, Sittampalam GS.

Nat Rev Drug Discov. 2011 Mar;10(3):188-95. doi: 10.1038/nrd3368. Review.

PMID:
21358738
13.

Stem cells in drug discovery, tissue engineering, and regenerative medicine: emerging opportunities and challenges.

Nirmalanandhan VS, Sittampalam GS.

J Biomol Screen. 2009 Aug;14(7):755-68. doi: 10.1177/1087057109336591. Epub 2009 Aug 12. Review.

PMID:
19675315
14.

A comparison of assay performance measures in screening assays: signal window, Z' factor, and assay variability ratio.

Iversen PW, Eastwood BJ, Sittampalam GS, Cox KL.

J Biomol Screen. 2006 Apr;11(3):247-52. Epub 2006 Feb 20.

PMID:
16490779
15.

Bioimaging in drug discovery sciences.

Sittampalam GS, Westmore M.

Anal Bioanal Chem. 2003 Nov;377(6):953-4. Epub 2003 Oct 16. No abstract available.

PMID:
14564446

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