Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 37


C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo.

Clough B, Finethy R, Khan RT, Fisch D, Jordan S, Patel H, Coers J, Frickel EM.

Wellcome Open Res. 2019 Aug 20;4:124. doi: 10.12688/wellcomeopenres.15329.1. eCollection 2019.


CD82 controls CpG-dependent TLR9 signaling.

Khan NS, Lukason DP, Feliu M, Ward RA, Lord AK, Reedy JL, Ramirez-Ortiz ZG, Tam JM, Kasperkovitz PV, Negoro PE, Vyas TD, Xu S, Brinkmann MM, Acharaya M, Artavanis-Tsakonas K, Frickel EM, Becker CE, Dagher Z, Kim YM, Latz E, Ploegh HL, Mansour MK, Miranti CK, Levitz SM, Vyas JM.

FASEB J. 2019 Nov;33(11):12500-12514. doi: 10.1096/fj.201901547R. Epub 2019 Aug 13.


Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis.

Fisch D, Bando H, Clough B, Hornung V, Yamamoto M, Shenoy AR, Frickel EM.

EMBO J. 2019 Jul 1;38(13):e100926. doi: 10.15252/embj.2018100926. Epub 2019 Jun 3.


Clonal and atypical Toxoplasma strain differences in virulence vary with mouse sub-species.

Hassan MA, Olijnik AA, Frickel EM, Saeij JP.

Int J Parasitol. 2019 Jan;49(1):63-70. doi: 10.1016/j.ijpara.2018.08.007. Epub 2018 Nov 22.


The Interplay of Host Autophagy and Eukaryotic Pathogens.

Evans RJ, Sundaramurthy V, Frickel EM.

Front Cell Dev Biol. 2018 Sep 13;6:118. doi: 10.3389/fcell.2018.00118. eCollection 2018. Review.


T Cell Receptor-Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103+ Memory Status of CD8 T Cells in the Brain.

Sanecka A, Yoshida N, Kolawole EM, Patel H, Evavold BD, Frickel EM.

Front Immunol. 2018 Jun 5;9:1290. doi: 10.3389/fimmu.2018.01290. eCollection 2018.


Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection.

Napolitano A, van der Veen AG, Bunyan M, Borg A, Frith D, Howell S, Kjaer S, Beling A, Snijders AP, Knobeloch KP, Frickel EM.

J Immunol. 2018 Jul 15;201(2):604-614. doi: 10.4049/jimmunol.1701322. Epub 2018 Jun 11.


Murine Gbp1 and Gbp2 are ubiquitinated independent of Toxoplasma gondii infection.

Encheva V, Foltz C, Snijders AP, Frickel EM.

BMC Res Notes. 2018 Mar 6;11(1):166. doi: 10.1186/s13104-018-3267-z.


Macrophage-Microbe Interactions: Lessons from the Zebrafish Model.

Yoshida N, Frickel EM, Mostowy S.

Front Immunol. 2017 Dec 1;8:1703. doi: 10.3389/fimmu.2017.01703. eCollection 2017. Review.


Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility.

Piro AS, Hernandez D, Luoma S, Feeley EM, Finethy R, Yirga A, Frickel EM, Lesser CF, Coers J.

MBio. 2017 Dec 12;8(6). pii: e01979-17. doi: 10.1128/mBio.01979-17.


Exposing Toxoplasma gondii hiding inside the vacuole: a role for GBPs, autophagy and host cell death.

Saeij JP, Frickel EM.

Curr Opin Microbiol. 2017 Dec;40:72-80. doi: 10.1016/j.mib.2017.10.021. Epub 2017 Nov 12. Review.


TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles.

Foltz C, Napolitano A, Khan R, Clough B, Hirst EM, Frickel EM.

Sci Rep. 2017 Jul 12;7(1):5209. doi: 10.1038/s41598-017-05487-7.


The Toxoplasma Parasitophorous Vacuole: An Evolving Host-Parasite Frontier.

Clough B, Frickel EM.

Trends Parasitol. 2017 Jun;33(6):473-488. doi: 10.1016/ Epub 2017 Mar 19. Review.


Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells.

Haldar AK, Piro AS, Finethy R, Espenschied ST, Brown HE, Giebel AM, Frickel EM, Nelson DE, Coers J.

MBio. 2016 Dec 13;7(6). pii: e01417-16. doi: 10.1128/mBio.01417-16.


Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions.

Swee LK, Tan ZW, Sanecka A, Yoshida N, Patel H, Grotenbreg G, Frickel EM, Ploegh HL.

Open Biol. 2016 Nov;6(11). pii: 160293.


K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells.

Clough B, Wright JD, Pereira PM, Hirst EM, Johnston AC, Henriques R, Frickel EM.

PLoS Pathog. 2016 Nov 22;12(11):e1006027. doi: 10.1371/journal.ppat.1006027. eCollection 2016 Nov.


Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute-phase Toxoplasma gondii burden.

Sanecka A, Yoshida N, Dougan SK, Jackson J, Shastri N, Ploegh H, Blanchard N, Frickel EM.

Immunology. 2016 Nov;149(3):270-279. doi: 10.1111/imm.12643. Epub 2016 Aug 17.


Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii.

Johnston AC, Piro A, Clough B, Siew M, Virreira Winter S, Coers J, Frickel EM.

Cell Microbiol. 2016 Aug;18(8):1056-64. doi: 10.1111/cmi.12579. Epub 2016 Mar 10.


Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins.

Haldar AK, Foltz C, Finethy R, Piro AS, Feeley EM, Pilla-Moffett DM, Komatsu M, Frickel EM, Coers J.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5628-37. doi: 10.1073/pnas.1515966112. Epub 2015 Sep 28.


RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.

Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4581-90. doi: 10.1073/pnas.1510031112. Epub 2015 Aug 3.

Supplemental Content

Loading ...
Support Center