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Items: 1 to 20 of 68

1.

Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy.

Verma M, Shimizu-Motohashi Y, Asakura Y, Ennen JP, Bosco J, Zhou Z, Fong GH, Josiah S, Keefe D, Asakura A.

PLoS Genet. 2019 Dec 26;15(12):e1008468. doi: 10.1371/journal.pgen.1008468. eCollection 2019 Dec.

2.

Neuron-derived VEGF contributes to cortical and hippocampal development independently of VEGFR1/2-mediated neurotrophism.

Okabe K, Fukada H, Tai-Nagara I, Ando T, Honda T, Nakajima K, Takeda N, Fong GH, Ema M, Kubota Y.

Dev Biol. 2019 Nov 30. pii: S0012-1606(19)30536-6. doi: 10.1016/j.ydbio.2019.11.016. [Epub ahead of print]

3.

Assembly of Bifunctional Aptamer-Fibrinogen Macromer for VEGF Delivery and Skin Wound Healing.

Zhao N, Coyne J, Xu M, Zhang X, Suzuki A, Shi P, Lai J, Fong GH, Xiong N, Wang Y.

Chem Mater. 2019 Feb 12;31(3):1006-1015. doi: 10.1021/acs.chemmater.8b04486. Epub 2019 Jan 11.

4.

Developmental vascular pruning in neonatal mouse retinas is programmed by the astrocytic oxygen-sensing mechanism.

Duan LJ, Fong GH.

Development. 2019 Apr 17;146(8). pii: dev175117. doi: 10.1242/dev.175117.

5.

Lacteal junction zippering protects against diet-induced obesity.

Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel SE, Camporez JP, Singh AK, Fong GH, Simons M, Tso P, Fernández-Hernando C, Shulman GI, Sessa WC, Eichmann A.

Science. 2018 Aug 10;361(6402):599-603. doi: 10.1126/science.aap9331.

6.

Ablation of endothelial VEGFR1 improves metabolic dysfunction by inducing adipose tissue browning.

Seki T, Hosaka K, Fischer C, Lim S, Andersson P, Abe M, Iwamoto H, Gao Y, Wang X, Fong GH, Cao Y.

J Exp Med. 2018 Feb 5;215(2):611-626. doi: 10.1084/jem.20171012. Epub 2018 Jan 5.

7.

Retinal Angiogenesis Regulates Astrocytic Differentiation in Neonatal Mouse Retinas by Oxygen Dependent Mechanisms.

Duan LJ, Pan SJ, Sato TN, Fong GH.

Sci Rep. 2017 Dec 14;7(1):17608. doi: 10.1038/s41598-017-17962-2.

8.

Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin.

Kobayashi H, Liu Q, Binns TC, Urrutia AA, Davidoff O, Kapitsinou PP, Pfaff AS, Olauson H, Wernerson A, Fogo AB, Fong GH, Gross KW, Haase VH.

J Clin Invest. 2016 May 2;126(5):1926-38. doi: 10.1172/JCI83551. Epub 2016 Apr 18.

9.

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.

Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, Keep RF, Schallert T, Tappero RV, Zhong J, Cho S, Maxfield FR, Holman TR, Culmsee C, Fong GH, Su Y, Ming GL, Song H, Cave JW, Schofield CJ, Colbourne F, Coppola G, Ratan RR.

Sci Transl Med. 2016 Mar 2;8(328):328ra29. doi: 10.1126/scitranslmed.aac6008.

10.

Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis.

Cao Z, Lis R, Ginsberg M, Chavez D, Shido K, Rabbany SY, Fong GH, Sakmar TP, Rafii S, Ding BS.

Nat Med. 2016 Feb;22(2):154-62. doi: 10.1038/nm.4035. Epub 2016 Jan 18.

11.

Vasculogenesis and Angiogenesis in VEGF Receptor-1 Deficient Mice.

Ho VC, Fong GH.

Methods Mol Biol. 2015;1332:161-76. doi: 10.1007/978-1-4939-2917-7_12.

12.

PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function.

Chen Y, Zhang HS, Fong GH, Xi QL, Wu GH, Bai CG, Ling ZQ, Fan L, Xu YM, Qin YQ, Yuan TL, Sun H, Fang J.

J Biol Chem. 2015 Aug 14;290(33):20580-9. doi: 10.1074/jbc.M115.653584. Epub 2015 Jun 29.

13.

Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.

Souma T, Nezu M, Nakano D, Yamazaki S, Hirano I, Sekine H, Dan T, Takeda K, Fong GH, Nishiyama A, Ito S, Miyata T, Yamamoto M, Suzuki N.

J Am Soc Nephrol. 2016 Feb;27(2):428-38. doi: 10.1681/ASN.2014121184. Epub 2015 Jun 8.

14.

Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes.

Tojo Y, Sekine H, Hirano I, Pan X, Souma T, Tsujita T, Kawaguchi S, Takeda N, Takeda K, Fong GH, Dan T, Ichinose M, Miyata T, Yamamoto M, Suzuki N.

Mol Cell Biol. 2015 Aug;35(15):2658-72. doi: 10.1128/MCB.00161-15. Epub 2015 May 26.

15.

Potential contributions of intimal and plaque hypoxia to atherosclerosis.

Fong GH.

Curr Atheroscler Rep. 2015 Jun;17(6):510. doi: 10.1007/s11883-015-0510-0. Review.

PMID:
25876920
16.

Deletion of prolyl hydroxylase domain proteins (PHD1, PHD3) stabilizes hypoxia inducible factor-1 alpha, promotes neovascularization, and improves perfusion in a murine model of hind-limb ischemia.

Rishi MT, Selvaraju V, Thirunavukkarasu M, Shaikh IA, Takeda K, Fong GH, Palesty JA, Sanchez JA, Maulik N.

Microvasc Res. 2015 Jan;97:181-8. doi: 10.1016/j.mvr.2014.10.009. Epub 2014 Nov 3.

PMID:
25446011
17.

PTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formation.

Qi Y, Liu J, Saadat S, Tian X, Han Y, Fong GH, Pandolfi PP, Lee LY, Li S.

Cell Death Differ. 2015 May;22(5):875-84. doi: 10.1038/cdd.2014.185. Epub 2014 Nov 14.

18.

Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver.

Duan LJ, Takeda K, Fong GH.

Am J Pathol. 2014 Apr;184(4):1240-1250. doi: 10.1016/j.ajpath.2013.12.014. Epub 2014 Feb 6.

19.

Hypoxia inducible factor-2α regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors.

Duan LJ, Takeda K, Fong GH.

PLoS One. 2014 Jan 27;9(1):e84736. doi: 10.1371/journal.pone.0084736. eCollection 2014.

20.

Improved vascular survival and growth in the mouse model of hindlimb ischemia by a remote signaling mechanism.

Takeda K, Duan LJ, Takeda H, Fong GH.

Am J Pathol. 2014 Mar;184(3):686-96. doi: 10.1016/j.ajpath.2013.11.032. Epub 2014 Jan 17.

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