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Items: 1 to 20 of 38


Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats.

García-Fuster MJ, Parsegian A, Watson SJ, Akil H, Flagel SB.

Psychopharmacology (Berl). 2017 Feb 16. doi: 10.1007/s00213-017-4566-0. [Epub ahead of print]


A food-predictive cue attributed with incentive salience engages subcortical afferents and efferents of the paraventricular nucleus of the thalamus.

Haight JL, Fuller ZL, Fraser KM, Flagel SB.

Neuroscience. 2017 Jan 6;340:135-152. doi: 10.1016/j.neuroscience.2016.10.043.


Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model.

Flagel SB, Chaudhury S, Waselus M, Kelly R, Sewani S, Clinton SM, Thompson RC, Watson SJ Jr, Akil H.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2861-70. doi: 10.1073/pnas.1520491113.


Examining the role of dopamine D2 and D3 receptors in Pavlovian conditioned approach behaviors.

Fraser KM, Haight JL, Gardner EL, Flagel SB.

Behav Brain Res. 2016 May 15;305:87-99. doi: 10.1016/j.bbr.2016.02.022.


Neuroscience of resilience and vulnerability for addiction medicine: From genes to behavior.

Morrow JD, Flagel SB.

Prog Brain Res. 2016;223:3-18. doi: 10.1016/bs.pbr.2015.09.004.


Lesions of the paraventricular nucleus of the thalamus differentially affect sign- and goal-tracking conditioned responses.

Haight JL, Fraser KM, Akil H, Flagel SB.

Eur J Neurosci. 2015 Oct;42(7):2478-88. doi: 10.1111/ejn.13031.


Individual variation in the propensity to attribute incentive salience to a food cue: influence of sex.

Pitchers KK, Flagel SB, O'Donnell EG, Woods LC, Sarter M, Robinson TE.

Behav Brain Res. 2015 Feb 1;278:462-9. doi: 10.1016/j.bbr.2014.10.036.


Individual variation in the motivational and neurobiological effects of an opioid cue.

Yager LM, Pitchers KK, Flagel SB, Robinson TE.

Neuropsychopharmacology. 2015 Mar 13;40(5):1269-77. doi: 10.1038/npp.2014.314.


The role of learning-related dopamine signals in addiction vulnerability.

Huys QJ, Tobler PN, Hasler G, Flagel SB.

Prog Brain Res. 2014;211:31-77. doi: 10.1016/B978-0-444-63425-2.00003-9. Review.


Experimental predictions drawn from a computational model of sign-trackers and goal-trackers.

Lesaint F, Sigaud O, Clark JJ, Flagel SB, Khamassi M.

J Physiol Paris. 2015 Feb-Jun;109(1-3):78-86. doi: 10.1016/j.jphysparis.2014.06.001.


Modelling individual differences in the form of Pavlovian conditioned approach responses: a dual learning systems approach with factored representations.

Lesaint F, Sigaud O, Flagel SB, Robinson TE, Khamassi M.

PLoS Comput Biol. 2014 Feb 13;10(2):e1003466. doi: 10.1371/journal.pcbi.1003466.


Variation in the form of Pavlovian conditioned approach behavior among outbred male Sprague-Dawley rats from different vendors and colonies: sign-tracking vs. goal-tracking.

Fitzpatrick CJ, Gopalakrishnan S, Cogan ES, Yager LM, Meyer PJ, Lovic V, Saunders BT, Parker CC, Gonzales NM, Aryee E, Flagel SB, Palmer AA, Robinson TE, Morrow JD.

PLoS One. 2013 Oct 1;8(10):e75042. doi: 10.1371/journal.pone.0075042.


Long-term effects of cocaine experience on neuroplasticity in the nucleus accumbens core of addiction-prone rats.

Waselus M, Flagel SB, Jedynak JP, Akil H, Robinson TE, Watson SJ Jr.

Neuroscience. 2013 Sep 17;248:571-84. doi: 10.1016/j.neuroscience.2013.06.042.


Differential impact of a complex environment on positive affect in an animal model of individual differences in emotionality.

Perez-Sepulveda JA, Flagel SB, Garcia-Fuster MJ, Slusky RJ, Aldridge JW, Watson S, Akil H.

Neuroscience. 2013 Sep 17;248:436-47. doi: 10.1016/j.neuroscience.2013.06.015.


Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics.

Parker CC, Chen H, Flagel SB, Geurts AM, Richards JB, Robinson TE, Solberg Woods LC, Palmer AA.

Neuropharmacology. 2014 Jan;76 Pt B:250-8. doi: 10.1016/j.neuropharm.2013.05.047.


Antecedents and consequences of drug abuse in rats selectively bred for high and low response to novelty.

Flagel SB, Waselus M, Clinton SM, Watson SJ, Akil H.

Neuropharmacology. 2014 Jan;76 Pt B:425-36. doi: 10.1016/j.neuropharm.2013.04.033. Review.


Cocaine withdrawal causes delayed dysregulation of stress genes in the hippocampus.

García-Fuster MJ, Flagel SB, Mahmood ST, Watson SJ, Akil H.

PLoS One. 2012;7(7):e42092. doi: 10.1371/journal.pone.0042092.


Neonatal fibroblast growth factor treatment enhances cocaine sensitization.

Clinton SM, Turner CA, Flagel SB, Simpson DN, Watson SJ, Akil H.

Pharmacol Biochem Behav. 2012 Nov;103(1):6-17.


Quantifying individual variation in the propensity to attribute incentive salience to reward cues.

Meyer PJ, Lovic V, Saunders BT, Yager LM, Flagel SB, Morrow JD, Robinson TE.

PLoS One. 2012;7(6):e38987. doi: 10.1371/journal.pone.0038987.

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