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Items: 1 to 20 of 44


Measuring appetitive conditioned responses in humans.

Wardle MC, Lopez-Gamundi P, Flagel SB.

Physiol Behav. 2018 May 1;188:140-150. doi: 10.1016/j.physbeh.2018.02.004. Epub 2018 Feb 9.


Transient inactivation of the paraventricular nucleus of the thalamus enhances cue-induced reinstatement in goal-trackers, but not sign-trackers.

Kuhn BN, Klumpner MS, Covelo IR, Campus P, Flagel SB.

Psychopharmacology (Berl). 2018 Apr;235(4):999-1014. doi: 10.1007/s00213-017-4816-1. Epub 2017 Dec 28.


A Translational Model to Assess Sign-Tracking and Goal-Tracking Behavior in Children.

Joyner MA, Gearhardt AN, Flagel SB.

Neuropsychopharmacology. 2018 Jan;43(1):228-229. doi: 10.1038/npp.2017.196. No abstract available.


The in Vivo Neurochemical Profile of Selectively Bred High-Responder and Low-Responder Rats Reveals Baseline, Cocaine-Evoked, and Novelty-Evoked Differences in Monoaminergic Systems.

Mabrouk OS, Han JL, Wong JT, Akil H, Kennedy RT, Flagel SB.

ACS Chem Neurosci. 2018 Apr 18;9(4):715-724. doi: 10.1021/acschemneuro.7b00294. Epub 2017 Dec 12.


Utilizing a unique animal model to better understand human temperament.

Turner CA, Flagel SB, Blandino P Jr, Watson SJ Jr, Akil H.

Curr Opin Behav Sci. 2017 Apr;14:108-114. doi: 10.1016/j.cobeha.2017.02.002. Epub 2017 Feb 24.


Neurobiological Basis of Individual Variation in Stimulus-Reward Learning.

Flagel SB, Robinson TE.

Curr Opin Behav Sci. 2017 Feb;13:178-185. doi: 10.1016/j.cobeha.2016.12.004. Epub 2017 Jan 5.


Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats.

GarcĂ­a-Fuster MJ, Parsegian A, Watson SJ, Akil H, Flagel SB.

Psychopharmacology (Berl). 2017 Apr;234(8):1293-1305. doi: 10.1007/s00213-017-4566-0. Epub 2017 Feb 16.


A food-predictive cue attributed with incentive salience engages subcortical afferents and efferents of the paraventricular nucleus of the thalamus.

Haight JL, Fuller ZL, Fraser KM, Flagel SB.

Neuroscience. 2017 Jan 6;340:135-152. doi: 10.1016/j.neuroscience.2016.10.043. Epub 2016 Oct 25.


Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model.

Flagel SB, Chaudhury S, Waselus M, Kelly R, Sewani S, Clinton SM, Thompson RC, Watson SJ Jr, Akil H.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2861-70. doi: 10.1073/pnas.1520491113. Epub 2016 Apr 25.


Examining the role of dopamine D2 and D3 receptors in Pavlovian conditioned approach behaviors.

Fraser KM, Haight JL, Gardner EL, Flagel SB.

Behav Brain Res. 2016 May 15;305:87-99. doi: 10.1016/j.bbr.2016.02.022. Epub 2016 Feb 22.


Neuroscience of resilience and vulnerability for addiction medicine: From genes to behavior.

Morrow JD, Flagel SB.

Prog Brain Res. 2016;223:3-18. doi: 10.1016/bs.pbr.2015.09.004. Epub 2015 Nov 23. Review.


Lesions of the paraventricular nucleus of the thalamus differentially affect sign- and goal-tracking conditioned responses.

Haight JL, Fraser KM, Akil H, Flagel SB.

Eur J Neurosci. 2015 Oct;42(7):2478-88. doi: 10.1111/ejn.13031. Epub 2015 Aug 28.


Individual variation in the propensity to attribute incentive salience to a food cue: influence of sex.

Pitchers KK, Flagel SB, O'Donnell EG, Woods LC, Sarter M, Robinson TE.

Behav Brain Res. 2015 Feb 1;278:462-9. doi: 10.1016/j.bbr.2014.10.036. Epub 2014 Oct 31.


Individual variation in the motivational and neurobiological effects of an opioid cue.

Yager LM, Pitchers KK, Flagel SB, Robinson TE.

Neuropsychopharmacology. 2015 Mar 13;40(5):1269-77. doi: 10.1038/npp.2014.314.


The role of learning-related dopamine signals in addiction vulnerability.

Huys QJ, Tobler PN, Hasler G, Flagel SB.

Prog Brain Res. 2014;211:31-77. doi: 10.1016/B978-0-444-63425-2.00003-9. Review.


Experimental predictions drawn from a computational model of sign-trackers and goal-trackers.

Lesaint F, Sigaud O, Clark JJ, Flagel SB, Khamassi M.

J Physiol Paris. 2015 Feb-Jun;109(1-3):78-86. doi: 10.1016/j.jphysparis.2014.06.001. Epub 2014 Jun 20.


A potential role for the paraventricular nucleus of the thalamus in mediating individual variation in Pavlovian conditioned responses.

Haight JL, Flagel SB.

Front Behav Neurosci. 2014 Mar 14;8:79. doi: 10.3389/fnbeh.2014.00079. eCollection 2014.


Modelling individual differences in the form of Pavlovian conditioned approach responses: a dual learning systems approach with factored representations.

Lesaint F, Sigaud O, Flagel SB, Robinson TE, Khamassi M.

PLoS Comput Biol. 2014 Feb 13;10(2):e1003466. doi: 10.1371/journal.pcbi.1003466. eCollection 2014 Feb.


Variation in the form of Pavlovian conditioned approach behavior among outbred male Sprague-Dawley rats from different vendors and colonies: sign-tracking vs. goal-tracking.

Fitzpatrick CJ, Gopalakrishnan S, Cogan ES, Yager LM, Meyer PJ, Lovic V, Saunders BT, Parker CC, Gonzales NM, Aryee E, Flagel SB, Palmer AA, Robinson TE, Morrow JD.

PLoS One. 2013 Oct 1;8(10):e75042. doi: 10.1371/journal.pone.0075042. eCollection 2013.


Long-term effects of cocaine experience on neuroplasticity in the nucleus accumbens core of addiction-prone rats.

Waselus M, Flagel SB, Jedynak JP, Akil H, Robinson TE, Watson SJ Jr.

Neuroscience. 2013 Sep 17;248:571-84. doi: 10.1016/j.neuroscience.2013.06.042. Epub 2013 Jun 28.

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