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Items: 1 to 20 of 24


Improving engraftment of hepatocyte transplantation using alpha-1 antitrypsin as an immune modulator.

Lee C, Dhawan A, Iansante V, Filippi C, Mitry R, Tang J, Walker S, Fernandez DaCosta R, Sinha S, Hughes RD, Koulmanda M, Fitzpatrick E.

J Mol Med (Berl). 2019 Apr;97(4):563-577. doi: 10.1007/s00109-019-01747-3. Epub 2019 Feb 28.


A New High Throughput Screening Platform for Cell Encapsulation in Alginate Hydrogel Shows Improved Hepatocyte Functions by Mesenchymal Stromal Cells Co-encapsulation.

Iansante V, Dhawan A, Masmoudi F, Lee CA, Fernandez-Dacosta R, Walker S, Fitzpatrick E, Mitry RR, Filippi C.

Front Med (Lausanne). 2018 Aug 9;5:216. doi: 10.3389/fmed.2018.00216. eCollection 2018.


Cryopreserved neonatal hepatocytes may be a source for transplantation: Evaluation of functionality toward clinical use.

Lee CA, Dhawan A, Iansante V, Lehec S, Khorsandi SE, Filippi C, Walker S, Fernandez-Dacosta R, Heaton N, Bansal S, Mitry RR, Fitzpatrick E.

Liver Transpl. 2018 Mar;24(3):394-406. doi: 10.1002/lt.25015.


Human hepatocyte transplantation for liver disease: current status and future perspectives.

Iansante V, Mitry RR, Filippi C, Fitzpatrick E, Dhawan A.

Pediatr Res. 2018 Jan;83(1-2):232-240. doi: 10.1038/pr.2017.284. Epub 2017 Dec 6. Review.


Cryopreservation of Hepatocyte Microbeads for Clinical Transplantation.

Jitraruch S, Dhawan A, Hughes RD, Filippi C, Lehec SC, Glover L, Mitry RR.

Cell Transplant. 2017 Aug;26(8):1341-1354. doi: 10.1177/0963689717720050.


Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes.

Qin HH, Filippi C, Sun S, Lehec S, Dhawan A, Hughes RD.

Stem Cell Res Ther. 2015 Dec 1;6:237. doi: 10.1186/s13287-015-0218-7.


Alginate microencapsulated hepatocytes optimised for transplantation in acute liver failure.

Jitraruch S, Dhawan A, Hughes RD, Filippi C, Soong D, Philippeos C, Lehec SC, Heaton ND, Longhi MS, Mitry RR.

PLoS One. 2014 Dec 1;9(12):e113609. doi: 10.1371/journal.pone.0113609. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119226.


A thyroid hormone receptor/KLF9 axis in human hepatocytes and pluripotent stem cells.

Cvoro A, Devito L, Milton FA, Noli L, Zhang A, Filippi C, Sakai K, Suh JH, H Sieglaff D, Dhawan A, Sakai T, Ilic D, Webb P.

Stem Cells. 2015 Feb;33(2):416-28. doi: 10.1002/stem.1875.


Toxicology of ZnO and TiO2 nanoparticles on hepatocytes: impact on metabolism and bioenergetics.

Filippi C, Pryde A, Cowan P, Lee T, Hayes P, Donaldson K, Plevris J, Stone V.

Nanotoxicology. 2015 Feb;9(1):126-34. doi: 10.3109/17435390.2014.895437. Epub 2014 Apr 8.


Current status of human hepatocyte transplantation and its potential for Wilson's disease.

Filippi C, Dhawan A.

Ann N Y Acad Sci. 2014 May;1315:50-5. doi: 10.1111/nyas.12386. Epub 2014 Mar 7. Review.


Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis.

Lockman KA, Baren JP, Pemberton CJ, Baghdadi H, Burgess KE, Plevris-Papaioannou N, Lee P, Howie F, Beckett G, Pryde A, Jaap AJ, Hayes PC, Filippi C, Plevris JN.

Liver Int. 2012 Aug;32(7):1079-92. doi: 10.1111/j.1478-3231.2012.02775.x. Epub 2012 Mar 19.


Chronic excessive alcohol consumption diagnosis: comparison between traditional biomarkers and ethyl glucuronide in hair, a study on a real population.

Morini L, Varango C, Filippi C, Rusca C, Danesino P, Cheli F, Fusini M, Iannello G, Groppi A.

Ther Drug Monit. 2011 Oct;33(5):654-7. doi: 10.1097/FTD.0b013e318232950f.


Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure.

Newsome PN, Henderson NC, Nelson LJ, Dabos C, Filippi C, Bellamy C, Howie F, Clutton RE, King T, Lee A, Hayes PC, Plevris JN.

BMC Gastroenterol. 2010 Mar 30;10:34. doi: 10.1186/1471-230X-10-34.


Hepatic endoderm differentiation from human embryonic stem cells.

Hannoun Z, Filippi C, Sullivan G, Hay DC, Iredale JP.

Curr Stem Cell Res Ther. 2010 Sep;5(3):233-44. Review.


Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling.

Hay DC, Fletcher J, Payne C, Terrace JD, Gallagher RC, Snoeys J, Black JR, Wojtacha D, Samuel K, Hannoun Z, Pryde A, Filippi C, Currie IS, Forbes SJ, Ross JA, Newsome PN, Iredale JP.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12301-6. doi: 10.1073/pnas.0806522105. Epub 2008 Aug 21.


Long term highly saturated fat diet does not induce NASH in Wistar rats.

Romestaing C, Piquet MA, Bedu E, Rouleau V, Dautresme M, Hourmand-Ollivier I, Filippi C, Duchamp C, Sibille B.

Nutr Metab (Lond). 2007 Feb 21;4:4.


Early cytotoxic effects of ochratoxin A in rat liver: a morphological, biochemical and molecular study.

Gagliano N, Donne ID, Torri C, Migliori M, Grizzi F, Milzani A, Filippi C, Annoni G, Colombo P, Costa F, Ceva-Grimaldi G, Bertelli AA, Giovannini L, Gioia M.

Toxicology. 2006 Aug 15;225(2-3):214-24. Epub 2006 Jun 10.


Polyunsaturated fatty acid deficiency reverses effects of alcohol on mitochondrial energy metabolism.

Piquet MA, Roulet M, Nogueira V, Filippi C, Sibille B, Hourmand-Ollivier I, Pilet M, Rouleau V, Leverve XM.

J Hepatol. 2004 Nov;41(5):721-9.


Improvement of C3A cell metabolism for usage in bioartificial liver support systems.

Filippi C, Keatch SA, Rangar D, Nelson LJ, Hayes PC, Plevris JN.

J Hepatol. 2004 Oct;41(4):599-605.


The mitochondrial consequences of uncoupling intact cells depend on the nature of the exogenous substrate.

Sibille B, Filippi C, Piquet MA, Leclercq P, Fontaine E, Ronot X, Rigoulet M, Leverve X.

Biochem J. 2001 Apr 1;355(Pt 1):231-5.

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