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Page 1
Opioid antagonist activity of naltrexone-derived bivalent ligands: importance of a properly oriented molecular scaffold to guide "address" recognition at kappa opioid receptors.
J Med Chem. 1996 Apr 26;39(9):1816-22. doi: 10.1021/jm950807f.
J Med Chem. 1996.
PMID: 8627605
Pyrrolomorphinans as delta opioid receptor antagonists. The role of steric hindrance in conferring selectivity.
Farouz-Grant F, Portoghese PS.
Farouz-Grant F, et al.
J Med Chem. 1997 Jun 20;40(13):1977-81. doi: 10.1021/jm970189y.
J Med Chem. 1997.
PMID: 9207938
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Structure-activity relationship of N17'-substituted norbinaltorphimine congeners. Role of the N17' basic group in the interaction with a putative address subsite on the kappa opioid receptor.
Portoghese PS, Lin CE, Farouz-Grant F, Takemori AE.
Portoghese PS, et al. Among authors: farouz grant f.
J Med Chem. 1994 May 13;37(10):1495-500. doi: 10.1021/jm00036a015.
J Med Chem. 1994.
PMID: 8182708
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7'-Substituted amino acid conjugates of naltrindole. Hydrophilic groups as determinants of selective antagonism of delta 1 opioid receptor-mediated antinociception in mice.
Portoghese PS, Farouz-Grant F, Sultana M, Takemori AE.
Portoghese PS, et al. Among authors: farouz grant f.
J Med Chem. 1995 Feb 3;38(3):402-7. doi: 10.1021/jm00003a002.
J Med Chem. 1995.
PMID: 7853332
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