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Year Number of Results
2015 2
2016 1
2017 1
2018 3
2019 2
2021 7
2022 1
2023 2
2024 0

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Page 1
Therapeutics Development for Alagille Syndrome.
Sanchez P, Farkhondeh A, Pavlinov I, Baumgaertel K, Rodems S, Zheng W. Sanchez P, et al. Among authors: farkhondeh a. Front Pharmacol. 2021 Aug 23;12:704586. doi: 10.3389/fphar.2021.704586. eCollection 2021. Front Pharmacol. 2021. PMID: 34497511 Free PMC article. Review.
Induced pluripotent stem cells for neural drug discovery.
Farkhondeh A, Li R, Gorshkov K, Chen KG, Might M, Rodems S, Lo DC, Zheng W. Farkhondeh A, et al. Drug Discov Today. 2019 Apr;24(4):992-999. doi: 10.1016/j.drudis.2019.01.007. Epub 2019 Jan 18. Drug Discov Today. 2019. PMID: 30664937 Free PMC article. Review.
Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936 T > A) mutation in JAGGED-1.
Brooks BM, Pradhan M, Cheng YS, Gorshkov K, Farkhondeh A, Chen CZ, Beers J, Liu C, Baumgaertel K, Rodems S, Zheng W. Brooks BM, et al. Among authors: farkhondeh a. Stem Cell Res. 2021 Jul;54:102447. doi: 10.1016/j.scr.2021.102447. Epub 2021 Jun 24. Stem Cell Res. 2021. PMID: 34198154 Free PMC article.
Generation and characterization of NGLY1 patient-derived midbrain organoids.
Abbott J, Tambe M, Pavlinov I, Farkhondeh A, Nguyen HN, Xu M, Pradhan M, York T, Might M, Baumgärtel K, Rodems S, Zheng W. Abbott J, et al. Among authors: farkhondeh a. Front Cell Dev Biol. 2023 Feb 16;11:1039182. doi: 10.3389/fcell.2023.1039182. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36875753 Free PMC article.
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease.
Vu M, Li R, Baskfield A, Lu B, Farkhondeh A, Gorshkov K, Motabar O, Beers J, Chen G, Zou J, Espejo-Mojica AJ, Rodríguez-López A, Alméciga-Díaz CJ, Barrera LA, Jiang X, Ory DS, Marugan JJ, Zheng W. Vu M, et al. Among authors: farkhondeh a. Orphanet J Rare Dis. 2018 Sep 17;13(1):152. doi: 10.1186/s13023-018-0886-3. Orphanet J Rare Dis. 2018. PMID: 30220252 Free PMC article.
Generation of two gene corrected human isogenic iPSC lines (NCATS-CL6104 and NCATS-CL6105) from a patient line (NCATS-CL6103) carrying a homozygous p.R401X mutation in the NGLY1 gene using CRISPR/Cas9.
Pavlinov I, Farkhondeh A, Yang S, Xu M, Cheng YS, Beers J, Zou J, Liu C, Might M, Rodems S, Baumgärtel K, Zheng W. Pavlinov I, et al. Among authors: farkhondeh a. Stem Cell Res. 2021 Oct;56:102554. doi: 10.1016/j.scr.2021.102554. Epub 2021 Sep 30. Stem Cell Res. 2021. PMID: 34619643 Free PMC article.
An induced pluripotent stem cell-derived NMJ platform for study of the NGLY1-Congenital Disorder of Deglycosylation.
Sasserath T, Robertson AL, Mendez R, Hays TT, Smith E, Cooper H, Akanda N, Rumsey JW, Guo X, Farkhondeh A, Pradhan M, Baumgaertel K, Might M, Rodems S, Zheng W, Hickman JJ. Sasserath T, et al. Among authors: farkhondeh a. Adv Ther (Weinh). 2022 Nov;5(11):2200009. doi: 10.1002/adtp.202200009. Epub 2022 Jul 15. Adv Ther (Weinh). 2022. PMID: 36589922 Free PMC article.
Generation of Alagille syndrome derived induced pluripotent stem cell line carrying heterozygous mutation in the JAGGED-1 gene at splicing site (Chr20: 10,629,709C>A) before exon 11.
Zhu W, Cheng YS, Xu M, Farkhondeh A, Beers J, Zou J, Liu C, Baumgaertel K, Rodems S, Zheng W. Zhu W, et al. Among authors: farkhondeh a. Stem Cell Res. 2021 May;53:102366. doi: 10.1016/j.scr.2021.102366. Epub 2021 Apr 27. Stem Cell Res. 2021. PMID: 34087995 Free PMC article.
17 results