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Items: 1 to 20 of 25

1.

Lung Microbiota Contribute to Pulmonary Inflammation and Disease Progression in Pulmonary Fibrosis.

O'Dwyer DN, Ashley SL, Gurczynski SJ, Xia M, Wilke C, Falkowski NR, Norman KC, Arnold KB, Huffnagle GB, Salisbury ML, Han MK, Flaherty KR, White ES, Martinez FJ, Erb-Downward JR, Murray S, Moore BB, Dickson RP.

Am J Respir Crit Care Med. 2019 Feb 21. doi: 10.1164/rccm.201809-1650OC. [Epub ahead of print]

PMID:
30789747
2.

Lung Dysbiosis, Inflammation, and Injury in Hematopoietic Cell Transplantation.

O'Dwyer DN, Zhou X, Wilke CA, Xia M, Falkowski NR, Norman KC, Arnold KB, Huffnagle GB, Murray S, Erb-Downward JR, Yanik GA, Moore BB, Dickson RP.

Am J Respir Crit Care Med. 2018 Nov 15;198(10):1312-1321. doi: 10.1164/rccm.201712-2456OC.

PMID:
29878854
3.

The Lung Microbiota of Healthy Mice Are Highly Variable, Cluster by Environment, and Reflect Variation in Baseline Lung Innate Immunity.

Dickson RP, Erb-Downward JR, Falkowski NR, Hunter EM, Ashley SL, Huffnagle GB.

Am J Respir Crit Care Med. 2018 Aug 15;198(4):497-508. doi: 10.1164/rccm.201711-2180OC.

PMID:
29533677
4.

Genome Sequences of 12 Pseudomonas lundensis Strains Isolated from the Lungs of Humans.

Scales BS, Erb-Downward JR, Falkowski NR, LiPuma JJ, Huffnagle GB.

Genome Announc. 2018 Feb 15;6(7). pii: e01461-17. doi: 10.1128/genomeA.01461-17.

5.

Bacterial Dissemination to the Brain in Sepsis.

Singer BH, Dickson RP, Denstaedt SJ, Newstead MW, Kim K, Falkowski NR, Erb-Downward JR, Schmidt TM, Huffnagle GB, Standiford TJ.

Am J Respir Crit Care Med. 2018 Mar 15;197(6):747-756. doi: 10.1164/rccm.201708-1559OC.

6.

Reply: Clinical Metagenomics for the Diagnosis of Hospital-acquired Infections: Promises and Hurdles.

Pendleton KM, Erb-Downward JR, Bao Y, Branton WR, Falkowski NR, Newton DW, Huffnagle GB, Dickson RP.

Am J Respir Crit Care Med. 2017 Dec 15;196(12):1618-1619. doi: 10.1164/rccm.201706-1144LE. No abstract available.

7.

Rapid Pathogen Identification in Bacterial Pneumonia Using Real-Time Metagenomics.

Pendleton KM, Erb-Downward JR, Bao Y, Branton WR, Falkowski NR, Newton DW, Huffnagle GB, Dickson RP.

Am J Respir Crit Care Med. 2017 Dec 15;196(12):1610-1612. doi: 10.1164/rccm.201703-0537LE. No abstract available.

8.

Bacterial Topography of the Healthy Human Lower Respiratory Tract.

Dickson RP, Erb-Downward JR, Freeman CM, McCloskey L, Falkowski NR, Huffnagle GB, Curtis JL.

MBio. 2017 Feb 14;8(1). pii: e02287-16. doi: 10.1128/mBio.02287-16.

9.

Role of interferon-γ and inflammatory monocytes in driving colonic inflammation during acute Clostridium difficile infection in mice.

McDermott AJ, Falkowski NR, McDonald RA, Frank CR, Pandit CR, Young VB, Huffnagle GB.

Immunology. 2017 Apr;150(4):468-477. doi: 10.1111/imm.12700. Epub 2017 Jan 30.

10.

Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome.

Dickson RP, Singer BH, Newstead MW, Falkowski NR, Erb-Downward JR, Standiford TJ, Huffnagle GB.

Nat Microbiol. 2016 Jul 18;1(10):16113. doi: 10.1038/nmicrobiol.2016.113.

11.

Interleukin-23 (IL-23), independent of IL-17 and IL-22, drives neutrophil recruitment and innate inflammation during Clostridium difficile colitis in mice.

McDermott AJ, Falkowski NR, McDonald RA, Pandit CR, Young VB, Huffnagle GB.

Immunology. 2016 Jan;147(1):114-24. doi: 10.1111/imm.12545. Epub 2015 Dec 2.

12.

The role of Gr-1(+) cells and tumour necrosis factor-α signalling during Clostridium difficile colitis in mice.

McDermott AJ, Higdon KE, Muraglia R, Erb-Downward JR, Falkowski NR, McDonald RA, Young VB, Huffnagle GB.

Immunology. 2015 Apr;144(4):704-16. doi: 10.1111/imm.12425.

13.

Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice.

Sadighi Akha AA, McDermott AJ, Theriot CM, Carlson PE Jr, Frank CR, McDonald RA, Falkowski NR, Bergin IL, Young VB, Huffnagle GB.

Immunology. 2015 Apr;144(4):587-97. doi: 10.1111/imm.12414.

14.

Role of GM-CSF in the inflammatory cytokine network that regulates neutrophil influx into the colonic mucosa during Clostridium difficile infection in mice.

McDermott AJ, Frank CR, Falkowski NR, McDonald RA, Young VB, Huffnagle GB.

Gut Microbes. 2014 Jul 1;5(4):476-84. doi: 10.4161/gmic.29964. Epub 2014 Jul 21.

15.

Modulation of post-antibiotic bacterial community reassembly and host response by Candida albicans.

Erb Downward JR, Falkowski NR, Mason KL, Muraglia R, Huffnagle GB.

Sci Rep. 2013;3:2191. doi: 10.1038/srep02191.

16.

Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response.

Sadighi Akha AA, Theriot CM, Erb-Downward JR, McDermott AJ, Falkowski NR, Tyra HM, Rutkowski DT, Young VB, Huffnagle GB.

Immunology. 2013 Sep;140(1):111-22. doi: 10.1111/imm.12122.

17.

Total parenteral nutrition-associated lamina propria inflammation in mice is mediated by a MyD88-dependent mechanism.

Miyasaka EA, Feng Y, Poroyko V, Falkowski NR, Erb-Downward J, Gillilland MG 3rd, Mason KL, Huffnagle GB, Teitelbaum DH.

J Immunol. 2013 Jun 15;190(12):6607-15. doi: 10.4049/jimmunol.1201746. Epub 2013 May 10.

18.

Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy.

Mason KL, Erb Downward JR, Mason KD, Falkowski NR, Eaton KA, Kao JY, Young VB, Huffnagle GB.

Infect Immun. 2012 Oct;80(10):3371-80. doi: 10.1128/IAI.00449-12. Epub 2012 Jul 9.

19.

Interleukin-17 drives pulmonary eosinophilia following repeated exposure to Aspergillus fumigatus conidia.

Murdock BJ, Falkowski NR, Shreiner AB, Sadighi Akha AA, McDonald RA, White ES, Toews GB, Huffnagle GB.

Infect Immun. 2012 Apr;80(4):1424-36. doi: 10.1128/IAI.05529-11. Epub 2012 Jan 17.

20.

Repeated exposure to Aspergillus fumigatus conidia results in CD4+ T cell-dependent and -independent pulmonary arterial remodeling in a mixed Th1/Th2/Th17 microenvironment that requires interleukin-4 (IL-4) and IL-10.

Shreiner AB, Murdock BJ, Sadighi Akha AA, Falkowski NR, Christensen PJ, White ES, Hogaboam CM, Huffnagle GB.

Infect Immun. 2012 Jan;80(1):388-97. doi: 10.1128/IAI.05530-11. Epub 2011 Nov 7.

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