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Exosomes: Fundamental Biology and Roles in Cardiovascular Physiology.
Ibrahim A, Marbán E. Ibrahim A, et al. Annu Rev Physiol. 2016;78:67-83. doi: 10.1146/annurev-physiol-021115-104929. Epub 2015 Nov 30. Annu Rev Physiol. 2016. PMID: 26667071 Free PMC article. Review.
The information within exosomes prominently includes their protein and RNA payloads. Exosomal microRNAs in particular can potently and fundamentally alter the transcriptome of recipient cells. Here we summarize what is known about exosome biogenesis, c …
The information within exosomes prominently includes their protein and RNA payloads. Exosomal microRNAs in particular can pote …
Mechanical force induces macrophage-derived exosomal UCHL3 promoting bone marrow mesenchymal stem cell osteogenesis by targeting SMAD1.
Pu P, Wu S, Zhang K, Xu H, Guan J, Jin Z, Sun W, Zhang H, Yan B. Pu P, et al. J Nanobiotechnology. 2023 Mar 14;21(1):88. doi: 10.1186/s12951-023-01836-z. J Nanobiotechnology. 2023. PMID: 36915132 Free PMC article.
Bone marrow-derived mesenchymal stem cells (BMSCs) play a fundamental role in osteogenesis during OTM. Macrophages are mechanosensitive cells that can regulate local inflammatory microenvironment and promote BMSCs osteogenesis by secreting diverse mediators. ...Impo …
Bone marrow-derived mesenchymal stem cells (BMSCs) play a fundamental role in osteogenesis during OTM. Macrophages are mechano …
Therapeutic and Diagnostic Translation of Extracellular Vesicles in Cardiovascular Diseases: Roadmap to the Clinic.
Sahoo S, Adamiak M, Mathiyalagan P, Kenneweg F, Kafert-Kasting S, Thum T. Sahoo S, et al. Circulation. 2021 Apr 6;143(14):1426-1449. doi: 10.1161/CIRCULATIONAHA.120.049254. Epub 2021 Apr 5. Circulation. 2021. PMID: 33819075 Free PMC article.
The potential of exosomes as effective communicators of biological signaling in myocardial function has previously been investigated, and a recent explosion in exosome research not only underscores their significance in cardiac physiology and pathology, but a …
The potential of exosomes as effective communicators of biological signaling in myocardial function has previously been investigated, …
Recent Advances in Experimental Models of Breast Cancer Exosome Secretion, Characterization and Function.
Pelissier Vatter FA, Lucotti S, Zhang H. Pelissier Vatter FA, et al. J Mammary Gland Biol Neoplasia. 2020 Dec;25(4):305-317. doi: 10.1007/s10911-020-09473-0. Epub 2020 Dec 22. J Mammary Gland Biol Neoplasia. 2020. PMID: 33351162 Review.
Exosomes are found in almost all physiological fluids including plasma, urine, saliva, and breast milk, providing a valuable resource for the development of non-invasive cancer biomarkers. Here, we review work on the role of exosomes in breast cancer p …
Exosomes are found in almost all physiological fluids including plasma, urine, saliva, and breast milk, providing a valuable r …