Engineered nasal cartilage for the repair of osteoarthritic knee cartilage defects.
Acevedo Rua L, Mumme M, Manferdini C, Darwiche S, Khalil A, Hilpert M, Buchner DA, Lisignoli G, Occhetta P, von Rechenberg B, Haug M, Schaefer DJ, Jakob M, Caplan A, Martin I, Barbero A, Pelttari K.
Acevedo Rua L, et al.
Sci Transl Med. 2021 Sep;13(609):eaaz4499. doi: 10.1126/scitranslmed.aaz4499. Epub 2021 Sep 1.
Sci Transl Med. 2021.
PMID: 34516821
We hypothesized that degenerative cartilage defects can be treated using nasal chondrocyte-based tissue-engineered cartilage (N-TEC). ...We further report that N-TEC survive and engraft in vivo in ectopic mouse models reproducing a human osteochondral …
We hypothesized that degenerative cartilage defects can be treated using nasal chondrocyte-based tissue-engineered c …