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Items: 19


A dual-AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock-out mice.

Al-Moyed H, Cepeda AP, Jung S, Moser T, Kügler S, Reisinger E.

EMBO Mol Med. 2019 Jan;11(1). pii: e9396. doi: 10.15252/emmm.201809396.


Activity-Dependent Phosphorylation by CaMKIIδ Alters the Ca2+ Affinity of the Multi-C2-Domain Protein Otoferlin.

Meese S, Cepeda AP, Gahlen F, Adams CM, Ficner R, Ricci AJ, Heller S, Reisinger E, Herget M.

Front Synaptic Neurosci. 2017 Oct 4;9:13. doi: 10.3389/fnsyn.2017.00013. eCollection 2017.


Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants.

Strenzke N, Chakrabarti R, Al-Moyed H, Müller A, Hoch G, Pangrsic T, Yamanbaeva G, Lenz C, Pan KT, Auge E, Geiss-Friedlander R, Urlaub H, Brose N, Wichmann C, Reisinger E.

EMBO J. 2016 Dec 1;35(23):2519-2535. Epub 2016 Oct 11.


Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing.

Jung S, Maritzen T, Wichmann C, Jing Z, Neef A, Revelo NH, Al-Moyed H, Meese S, Wojcik SM, Panou I, Bulut H, Schu P, Ficner R, Reisinger E, Rizzoli SO, Neef J, Strenzke N, Haucke V, Moser T.

EMBO J. 2015 Nov 3;34(21):2686-702. doi: 10.15252/embj.201591885. Epub 2015 Oct 7.


Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

Vogl C, Cooper BH, Neef J, Wojcik SM, Reim K, Reisinger E, Brose N, Rhee JS, Moser T, Wichmann C.

J Cell Sci. 2015 Feb 15;128(4):638-44. doi: 10.1242/jcs.162099. Epub 2015 Jan 20.


A new probe for super-resolution imaging of membranes elucidates trafficking pathways.

Revelo NH, Kamin D, Truckenbrodt S, Wong AB, Reuter-Jessen K, Reisinger E, Moser T, Rizzoli SO.

J Cell Biol. 2014 May 26;205(4):591-606. doi: 10.1083/jcb.201402066.


Otoferlin: a multi-C2 domain protein essential for hearing.

Pangršič T, Reisinger E, Moser T.

Trends Neurosci. 2012 Nov;35(11):671-80. doi: 10.1016/j.tins.2012.08.002. Epub 2012 Sep 7. Review.


Mice do not require auditory input for the normal development of their ultrasonic vocalizations.

Hammerschmidt K, Reisinger E, Westekemper K, Ehrenreich L, Strenzke N, Fischer J.

BMC Neurosci. 2012 Apr 25;13:40. doi: 10.1186/1471-2202-13-40.


Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.

Reisinger E, Bresee C, Neef J, Nair R, Reuter K, Bulankina A, Nouvian R, Koch M, Bückers J, Kastrup L, Roux I, Petit C, Hell SW, Brose N, Rhee JS, Kügler S, Brigande JV, Moser T.

J Neurosci. 2011 Mar 30;31(13):4886-95. doi: 10.1523/JNEUROSCI.5122-10.2011.


Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins.

Nouvian R, Neef J, Bulankina AV, Reisinger E, Pangršič T, Frank T, Sikorra S, Brose N, Binz T, Moser T.

Nat Neurosci. 2011 Apr;14(4):411-3. doi: 10.1038/nn.2774. Epub 2011 Mar 6.


The crystal structure of the C₂A domain of otoferlin reveals an unconventional top loop region.

Helfmann S, Neumann P, Tittmann K, Moser T, Ficner R, Reisinger E.

J Mol Biol. 2011 Feb 25;406(3):479-90. doi: 10.1016/j.jmb.2010.12.031. Epub 2011 Jan 7.


Gene expression associated with the onset of hearing detected by differential display in rat organ of Corti.

Reisinger E, Meintrup D, Oliver D, Fakler B.

Eur J Hum Genet. 2010 Dec;18(12):1327-32. doi: 10.1038/ejhg.2010.111. Epub 2010 Jul 21.


Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells.

Pangrsic T, Lasarow L, Reuter K, Takago H, Schwander M, Riedel D, Frank T, Tarantino LM, Bailey JS, Strenzke N, Brose N, Müller U, Reisinger E, Moser T.

Nat Neurosci. 2010 Jul;13(7):869-76. doi: 10.1038/nn.2578. Epub 2010 Jun 20.


Differential dependence of phasic transmitter release on synaptotagmin 1 at GABAergic and glutamatergic hippocampal synapses.

Kerr AM, Reisinger E, Jonas P.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15581-6. doi: 10.1073/pnas.0800621105. Epub 2008 Oct 1.


BKCa-Cav channel complexes mediate rapid and localized Ca2+-activated K+ signaling.

Berkefeld H, Sailer CA, Bildl W, Rohde V, Thumfart JO, Eble S, Klugbauer N, Reisinger E, Bischofberger J, Oliver D, Knaus HG, Schulte U, Fakler B.

Science. 2006 Oct 27;314(5799):615-20.


Hyperpolarization-activated cation channels in fast-spiking interneurons of rat hippocampus.

Aponte Y, Lien CC, Reisinger E, Jonas P.

J Physiol. 2006 Jul 1;574(Pt 1):229-43. Epub 2006 May 11.


A statistical model providing comprehensive predictions for the mRNA differential display.

Meintrup D, Reisinger E.

Bioinformatics. 2005 Oct 15;21(20):3880-6. Epub 2005 Aug 18.


Cod106, a novel synaptic protein expressed in sensory hair cells of the inner ear and in CNS neurons.

Reisinger E, Zimmermann U, Knipper M, Ludwig J, Klöcker N, Fakler B, Oliver D.

Mol Cell Neurosci. 2005 Jan;28(1):106-17.


Memantine inhibits efferent cholinergic transmission in the cochlea by blocking nicotinic acetylcholine receptors of outer hair cells.

Oliver D, Ludwig J, Reisinger E, Zoellner W, Ruppersberg JP, Fakler B.

Mol Pharmacol. 2001 Jul;60(1):183-9.


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