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Immunodepletion and Immunopurification as Approaches for CSN Research.

Golan A, Wei N, Pick E.

Methods Mol Biol. 2016;1449:103-16. doi: 10.1007/978-1-4939-3756-1_4.


Yeast as a tool to select inhibitors of the cullin deneddylating enzyme Csn5.

Cirigliano A, Stirpe A, Menta S, Mori M, Dell'Edera D, Pick E, Negri R, Botta B, Rinaldi T.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):1632-7. doi: 10.3109/14756366.2016.1160901. Epub 2016 Mar 30.


Aeromonas chitinase degrades chironomid egg masses.

Laviad S, Golan A, Shaked T, Vaizel-Ohayon D, Halpern M, Pick E.

Environ Microbiol Rep. 2016 Feb;8(1):30-7. doi: 10.1111/1758-2229.12347. Epub 2015 Dec 21.


Base-CP proteasome can serve as a platform for stepwise lid formation.

Yu Z, Livnat-Levanon N, Kleifeld O, Mansour W, Nakasone MA, Castaneda CA, Dixon EK, Fushman D, Reis N, Pick E, Glickman MH.

Biosci Rep. 2015 Jan 27;35(3). pii: e00194. doi: 10.1042/BSR20140173.


Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN.

Pick E, Bramasole L.

Biochem Soc Trans. 2014 Dec;42(6):1786-91. doi: 10.1042/BST20140227. Review.


Cullin E3 ligases and their rewiring by viral factors.

Mahon C, Krogan NJ, Craik CS, Pick E.

Biomolecules. 2014 Oct 13;4(4):897-930. doi: 10.3390/biom4040897. Review.


Targeted degradation of abscisic acid receptors is mediated by the ubiquitin ligase substrate adaptor DDA1 in Arabidopsis.

Irigoyen ML, Iniesto E, Rodriguez L, Puga MI, Yanagawa Y, Pick E, Strickland E, Paz-Ares J, Wei N, De Jaeger G, Rodriguez PL, Deng XW, Rubio V.

Plant Cell. 2014 Feb;26(2):712-28. doi: 10.1105/tpc.113.122234. Epub 2014 Feb 21.


The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae.

Licursi V, Salvi C, De Cesare V, Rinaldi T, Mattei B, Fabbri C, Serino G, Bramasole L, Zimbler JZ, Pick E, Barnes BM, Bard M, Negri R.

FEBS J. 2014 Jan;281(1):175-90. doi: 10.1111/febs.12584. Epub 2013 Nov 25.


COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phase.

Liu C, Guo LQ, Menon S, Jin D, Pick E, Wang X, Deng XW, Wei N.

J Biol Chem. 2013 Jul 12;288(28):20443-52. doi: 10.1074/jbc.M113.468959. Epub 2013 May 20.


Duplication and familial promiscuity within the proteasome lid and COP9 signalosome kin complexes.

Serino G, Pick E.

Plant Sci. 2013 Apr;203-204:89-97. doi: 10.1016/j.plantsci.2012.12.018. Epub 2013 Jan 5. Review.


Formation of alternative proteasomes: same lady, different cap?

Pick E, Berman TS.

FEBS Lett. 2013 Mar 1;587(5):389-93. doi: 10.1016/j.febslet.2013.01.014. Epub 2013 Jan 17.


The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain.

Pick E, Golan A, Zimbler JZ, Guo L, Sharaby Y, Tsuge T, Hofmann K, Wei N.

PLoS One. 2012;7(8):e43980. doi: 10.1371/journal.pone.0043980. Epub 2012 Aug 30.


Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome.

Yu Z, Kleifeld O, Lande-Atir A, Bsoul M, Kleiman M, Krutauz D, Book A, Vierstra RD, Hofmann K, Reis N, Glickman MH, Pick E.

Mol Biol Cell. 2011 Apr;22(7):911-20. doi: 10.1091/mbc.E10-08-0655. Epub 2011 Feb 2.


Centrosomal Chk2 in DNA damage responses and cell cycle progression.

Golan A, Pick E, Tsvetkov L, Nadler Y, Kluger H, Stern DF.

Cell Cycle. 2010 Jul 1;9(13):2647-56.


PCI complexes: Beyond the proteasome, CSN, and eIF3 Troika.

Pick E, Hofmann K, Glickman MH.

Mol Cell. 2009 Aug 14;35(3):260-4. doi: 10.1016/j.molcel.2009.07.009. Review.


Phosphatidylinositol-3-kinase as a therapeutic target in melanoma.

Aziz SA, Davies M, Pick E, Zito C, Jilaveanu L, Camp RL, Rimm DL, Kluger Y, Kluger HM.

Clin Cancer Res. 2009 May 1;15(9):3029-36. doi: 10.1158/1078-0432.CCR-08-2768. Epub 2009 Apr 21.


In the land of the rising sun with the COP9 signalosome and related Zomes. Symposium on the COP9 signalosome, Proteasome and eIF3.

Pick E, Pintard L.

EMBO Rep. 2009 Apr;10(4):343-8. doi: 10.1038/embor.2009.27. Epub 2009 Mar 13. Review. No abstract available.


Assessing expression of apoptotic markers using large cohort tissue microarrays.

Pick E, McCarthy MM, Kluger HM.

Methods Mol Biol. 2008;414:83-93. Review.


Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes.

Pick E, Lau OS, Tsuge T, Menon S, Tong Y, Dohmae N, Plafker SM, Deng XW, Wei N.

Mol Cell Biol. 2007 Jul;27(13):4708-19. Epub 2007 Apr 23.


High HSP90 expression is associated with decreased survival in breast cancer.

Pick E, Kluger Y, Giltnane JM, Moeder C, Camp RL, Rimm DL, Kluger HM.

Cancer Res. 2007 Apr 1;67(7):2932-7.

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