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Items: 18

1.

Editorial overview: Allergy and hypersensitivity: Emerging concepts in allergy and type 2 immunity.

Boyman O, Eggel A, Noti M.

Curr Opin Immunol. 2018 Oct;54:iii-v. doi: 10.1016/j.coi.2018.10.002. No abstract available.

PMID:
30342706
2.

Targeting IgE in allergic disease.

Gasser P, Eggel A.

Curr Opin Immunol. 2018 Oct;54:86-92. doi: 10.1016/j.coi.2018.05.015. Epub 2018 Jul 4. Review.

PMID:
29986302
3.

IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils.

Zellweger F, Buschor P, Hobi G, Brigger D, Dahinden CA, Villiger PM, Eggel A.

Cell Death Dis. 2018 May 1;9(5):510. doi: 10.1038/s41419-018-0526-9.

4.

A novel bispecific DARPin targeting FcγRIIB and FcεRI-bound IgE inhibits allergic responses.

Zellweger F, Gasser P, Brigger D, Buschor P, Vogel M, Eggel A.

Allergy. 2017 Aug;72(8):1174-1183. doi: 10.1111/all.13109. Epub 2017 Jan 24.

PMID:
27997998
5.

IgE-associated allergic disorders: recent advances in etiology, diagnosis, and treatment.

Zellweger F, Eggel A.

Allergy. 2016 Dec;71(12):1652-1661. doi: 10.1111/all.13059. Review.

PMID:
27709638
6.

Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.

Pennington LF, Tarchevskaya S, Brigger D, Sathiyamoorthy K, Graham MT, Nadeau KC, Eggel A, Jardetzky TS.

Nat Commun. 2016 May 19;7:11610. doi: 10.1038/ncomms11610.

7.

β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis.

Smith LK, He Y, Park JS, Bieri G, Snethlage CE, Lin K, Gontier G, Wabl R, Plambeck KE, Udeochu J, Wheatley EG, Bouchard J, Eggel A, Narasimha R, Grant JL, Luo J, Wyss-Coray T, Villeda SA.

Nat Med. 2015 Aug;21(8):932-7. doi: 10.1038/nm.3898. Epub 2015 Jul 6.

8.

NADPH oxidase-independent formation of extracellular DNA traps by basophils.

Morshed M, Hlushchuk R, Simon D, Walls AF, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon HU, Yousefi S.

J Immunol. 2014 Jun 1;192(11):5314-23. doi: 10.4049/jimmunol.1303418. Epub 2014 Apr 25.

9.

Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells.

Eggel A, Baravalle G, Hobi G, Kim B, Buschor P, Forrer P, Shin JS, Vogel M, Stadler BM, Dahinden CA, Jardetzky TS.

J Allergy Clin Immunol. 2014 Jun;133(6):1709-19.e8. doi: 10.1016/j.jaci.2014.02.005. Epub 2014 Mar 15.

10.

Improved FcγRIIb targeting functionally translates into enhanced inhibition of basophil activation.

Buschor P, Eggel A, Zellweger F, Stadler BM, Vogel M.

Int Arch Allergy Immunol. 2014;163(3):206-14. doi: 10.1159/000358487. Epub 2014 Feb 14.

PMID:
24557487
11.

A revival of parabiosis in biomedical research.

Eggel A, Wyss-Coray T.

Swiss Med Wkly. 2014 Feb 4;144:w13914. doi: 10.4414/smw.2014.13914. Review.

12.

Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor.

Kim B, Eggel A, Tarchevskaya SS, Vogel M, Prinz H, Jardetzky TS.

Nature. 2012 Nov 22;491(7425):613-7. doi: 10.1038/nature11546. Epub 2012 Oct 28.

13.

A time-resolved fluorescence resonance energy transfer assay suitable for high-throughput screening for inhibitors of immunoglobulin E-receptor interactions.

Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS.

Anal Biochem. 2012 Dec 15;431(2):84-9. doi: 10.1016/j.ab.2012.09.010. Epub 2012 Sep 18.

14.

An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation.

Wurzburg BA, Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS.

J Biol Chem. 2012 Oct 19;287(43):36251-7. doi: 10.1074/jbc.M112.407502. Epub 2012 Sep 4.

15.

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T.

Nature. 2011 Aug 31;477(7362):90-4. doi: 10.1038/nature10357.

16.

Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein.

Eggel A, Buschor P, Baumann MJ, Amstutz P, Stadler BM, Vogel M.

Allergy. 2011 Jul;66(7):961-8. doi: 10.1111/j.1398-9995.2011.02546.x. Epub 2011 Jan 28.

PMID:
21272035
17.

DARPins against a functional IgE epitope.

Baumann MJ, Eggel A, Amstutz P, Stadler BM, Vogel M.

Immunol Lett. 2010 Oct 30;133(2):78-84. doi: 10.1016/j.imlet.2010.07.005. Epub 2010 Jul 29.

PMID:
20673836
18.

DARPins as bispecific receptor antagonists analyzed for immunoglobulin E receptor blockage.

Eggel A, Baumann MJ, Amstutz P, Stadler BM, Vogel M.

J Mol Biol. 2009 Oct 30;393(3):598-607. doi: 10.1016/j.jmb.2009.08.014. Epub 2009 Aug 13.

PMID:
19683003

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