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BMJ Case Rep. 2010;2010. pii: bcr06.2009.2019. doi: 10.1136/bcr.06.2009.2019. Epub 2010 Jan 13.

Effect of Lactobacillus casei on Streptococcus bovis in faecal flora.

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Osaka Medical College, Division of Preventive and Social Medicine, Department of Hygiene and Public Health, 2-7 Daigakutyo Takatsuki City Osaka, Takatsuki, 569-8686, Japan.


Bacteraemia caused by Streptococcus bovis is often associated with colorectal tumours. Also, experimental studies have been proposed that S bovis acts as a promoter of tumours. We report the case of a man with colon adenoma who had a high proportion of S bovis in his faecal flora. He was treated with a Lactobacillus casei preparation (BLP) and the effect on the faecal flora was examined. L casei reduced the proportion of S bovis (from 43% down to 9%), and the effect continued after the administration of BLP was stopped. Our data indicate that BLP can repress the excessive colonisation of S bovis.

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