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Items: 1 to 20 of 117

1.

The Foundation Fighting Blindness Plays an Essential and Expansive Role in Driving Genetic Research for Inherited Retinal Diseases.

Shaberman B, Durham T.

Genes (Basel). 2019 Jul 6;10(7). pii: E511. doi: 10.3390/genes10070511.

PMID:
31284566
Free Article
2.

Chemistry, pharmacology, and cellular uptake mechanisms of thiometallate sulfide donors.

Durham T, Zander D, Stomeo N, Minnion M, Hogarth G, Feelisch M, Singer M, Dyson A.

Br J Pharmacol. 2019 Mar 29. doi: 10.1111/bph.14670. [Epub ahead of print]

PMID:
30924528
3.

How Did These Data Get Here? Recommendations for the Analysis of Data From ClinicalTrials.gov.

Durham TA.

Ther Innov Regul Sci. 2018 Nov 9:2168479018811825. doi: 10.1177/2168479018811825. [Epub ahead of print]

PMID:
30411627
4.

A Phase 2 Controlled Study of SB206, a Topical Nitric Oxide-Releasing Drug for Extragenital Wart Treatment.

Tyring SK, Rosen T, Berman B, Stasko N, Durham T, Maeda-Chubachi T.

J Drugs Dermatol. 2018 Oct 1;17(10):1100-1105.

PMID:
30365591
5.

Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.

Brooks HB, Meier TI, Geeganage S, Fales KR, Thrasher KJ, Konicek SA, Spencer CD, Thibodeaux S, Foreman RT, Hui YH, Roth KD, Qian YW, Wang T, Luo S, Torrado A, Si C, Toth JL, Mc Cowan JR, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Wang Y, Wu Z, Iversen PW, Njoroge FG.

Sci Rep. 2018 Oct 18;8(1):15458. doi: 10.1038/s41598-018-33453-4.

6.

A Phase 2, Controlled, Dose-Ranging Study of SB208, an Investigational Topical Nitric Oxide-Releasing Drug, for the Treatment of Tinea Pedis.

Elewski BE, Kircik LH, Stasko N, De Leon E, Enloe C, Durham T, Maeda-Chubachi T.

J Drugs Dermatol. 2018 Aug 1;17(8):888-893.

PMID:
30124729
7.

Functional characterization of enhancer evolution in the primate lineage.

Klein JC, Keith A, Agarwal V, Durham T, Shendure J.

Genome Biol. 2018 Jul 25;19(1):99. doi: 10.1186/s13059-018-1473-6.

8.

Anger as an underlying dimension of posttraumatic stress disorder.

Durham TA, Byllesby BM, Lv X, Elhai JD, Wang L.

Psychiatry Res. 2018 Sep;267:535-540. doi: 10.1016/j.psychres.2018.06.011. Epub 2018 Jun 12.

PMID:
29980134
9.

PREDICTD PaRallel Epigenomics Data Imputation with Cloud-based Tensor Decomposition.

Durham TJ, Libbrecht MW, Howbert JJ, Bilmes J, Noble WS.

Nat Commun. 2018 Apr 11;9(1):1402. doi: 10.1038/s41467-018-03635-9.

10.

CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis.

Prentice KJ, Wendell SG, Liu Y, Eversley JA, Salvatore SR, Mohan H, Brandt SL, Adams AC, Serena Wang X, Wei D, FitzGerald GA, Durham TB, Hammond CD, Sloop KW, Skarke C, Schopfer FJ, Wheeler MB.

EBioMedicine. 2018 Jan;27:200-213. doi: 10.1016/j.ebiom.2017.12.019. Epub 2017 Dec 19.

11.

The ModERN Resource: Genome-Wide Binding Profiles for Hundreds of Drosophila and Caenorhabditis elegans Transcription Factors.

Kudron MM, Victorsen A, Gevirtzman L, Hillier LW, Fisher WW, Vafeados D, Kirkey M, Hammonds AS, Gersch J, Ammouri H, Wall ML, Moran J, Steffen D, Szynkarek M, Seabrook-Sturgis S, Jameel N, Kadaba M, Patton J, Terrell R, Corson M, Durham TJ, Park S, Samanta S, Han M, Xu J, Yan KK, Celniker SE, White KP, Ma L, Gerstein M, Reinke V, Waterston RH.

Genetics. 2018 Mar;208(3):937-949. doi: 10.1534/genetics.117.300657. Epub 2017 Dec 28.

12.

Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.

Bueno AB, Agejas J, Broughton H, Dally R, Durham TB, Espinosa JF, González R, Hahn PJ, Marcos A, Rodríguez R, Sanz G, Soriano JF, Timm D, Vidal P, Yang HC, McCarthy JR.

J Med Chem. 2017 Dec 14;60(23):9807-9820. doi: 10.1021/acs.jmedchem.7b01304. Epub 2017 Nov 28.

PMID:
29088532
13.

Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model.

Fales KR, Njoroge FG, Brooks HB, Thibodeaux S, Torrado A, Si C, Toth JL, Mc Cowan JR, Roth KD, Thrasher KJ, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Margolis BJ, Wu Z, Wang Y, Atwell S, Wang J, Hui YH, Meier TI, Konicek SA, Geeganage S.

J Med Chem. 2017 Dec 14;60(23):9599-9616. doi: 10.1021/acs.jmedchem.7b01046. Epub 2017 Nov 9.

PMID:
29072452
14.

Utilization of Standard and Target-Specific Oral Anticoagulants Among Adults in the United Kingdom With Incident Atrial Fibrillation.

Durham TA, Hassmiller Lich K, Viera AJ, Fine JP, Mukherjee J, Weinberger M, Dusetzina SB.

Am J Cardiol. 2017 Nov 15;120(10):1820-1829. doi: 10.1016/j.amjcard.2017.07.091. Epub 2017 Aug 12.

PMID:
28867127
15.

The 7-factor hybrid model of DSM-5 PTSD symptoms and alcohol consumption and consequences in a national sample of trauma-exposed veterans.

Claycomb Erwin M, Charak R, Durham TA, Armour C, Lv X, Southwick SM, Elhai JD, Pietrzak RH.

J Anxiety Disord. 2017 Oct;51:14-21. doi: 10.1016/j.janxdis.2017.08.001. Epub 2017 Aug 6.

PMID:
28843574
16.

A Highly Selective Hydantoin Inhibitor of Aggrecanase-1 and Aggrecanase-2 with a Low Projected Human Dose.

Durham TB, Marimuthu J, Toth JL, Liu C, Adams L, Mudra DR, Swearingen C, Lin C, Chambers MG, Thirunavukkarasu K, Wiley MR.

J Med Chem. 2017 Jul 13;60(13):5933-5939. doi: 10.1021/acs.jmedchem.7b00650. Epub 2017 Jun 29.

PMID:
28613895
17.

Cost-Effectiveness Analysis of Four Simulated Colorectal Cancer Screening Interventions, North Carolina.

Hassmiller Lich K, Cornejo DA, Mayorga ME, Pignone M, Tangka FK, Richardson LC, Kuo TM, Meyer AM, Hall IJ, Smith JL, Durham TA, Chall SA, Crutchfield TM, Wheeler SB.

Prev Chronic Dis. 2017 Feb 23;14:E18. doi: 10.5888/pcd14.160158.

18.

Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic Acid (CMPF) and Effects on in Vitro Insulin Secretion.

Nagy E, Liu Y, Prentice KJ, Sloop KW, Sanders PE, Batchuluun B, Hammond CD, Wheeler MB, Durham TB.

J Med Chem. 2017 Mar 9;60(5):1860-1875. doi: 10.1021/acs.jmedchem.6b01668. Epub 2017 Feb 27.

PMID:
28171722
19.

Latent classes of childhood poly-victimization and associations with suicidal behavior among adult trauma victims: Moderating role of anger.

Charak R, Byllesby BM, Roley ME, Claycomb MA, Durham TA, Ross J, Armour C, Elhai JD.

Child Abuse Negl. 2016 Dec;62:19-28. doi: 10.1016/j.chiabu.2016.10.010. Epub 2016 Oct 22.

PMID:
27780110
20.

Relations between anger and DSM-5 posttraumatic stress disorder symptoms.

Durham TA, Byllesby BM, Armour C, Forbes D, Elhai JD.

Psychiatry Res. 2016 Oct 30;244:403-9. doi: 10.1016/j.psychres.2016.08.004. Epub 2016 Aug 5.

PMID:
27525831

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